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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A026
  • locus tag: T308_03905 [new locus tag: T308_RS03960 ]
  • pan locus tag?: PNEUPAN002749000
  • symbol: T308_03905
  • pan gene symbol?: —
  • synonym:
  • product: transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: T308_03905 [new locus tag: T308_RS03960 ]
  • symbol: T308_03905
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 759515..759754
  • length: 240
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGAGTATTAAAACTATAAGGAGGACGAAGGTGGCTAAAAATTTAAAATTAAAATTAGCT
    CGGGTAGAGCGTGATTTAACACAAGGTCAACTGGCAGAGGCTGTCGGGGTGACACGCCAG
    ACTATTGGTTTGATAGAGGCGGGAAAATACAATCCCAGTCTCTCGCTCTGCCAGTCTATT
    TGCAGATGTTTAGGGAAAACCCTAGACCAACTATTTTGGGAGGAAGAAGATGAAAAATAG
    60
    120
    180
    240

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: T308_03905 [new locus tag: T308_RS03960 ]
  • symbol: T308_03905
  • description: transcriptional regulator
  • length: 79
  • theoretical pI: 9.3974
  • theoretical MW: 8935.39
  • GRAVY: -0.362025

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 42.1)
    and 5 more
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 15.2)
    Genetic information processing Mobile and extrachromosomal element functions Other addiction module antidote protein, HigA family (TIGR02607; HMM-score: 14.3)
    Signal transduction Regulatory functions DNA interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 14.3)
    Signal transduction Regulatory functions Protein interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 14.3)
    probable regulatory domain (TIGR03879; HMM-score: 13.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 56.8)
    and 13 more
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 35.4)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 30.1)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 19)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 17.6)
    HTH_25; Helix-turn-helix domain (PF13413; HMM-score: 17.5)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 15.3)
    MarR_2; MarR family (PF12802; HMM-score: 15.3)
    YdaS_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT (PF15943; HMM-score: 15)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 14.4)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 14.1)
    HTH_11; HTH domain (PF08279; HMM-score: 13.9)
    HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 13.2)
    MerR; MerR family regulatory protein (PF00376; HMM-score: 9.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.059477
    • TAT(Tat/SPI): 0.004179
    • LIPO(Sec/SPII): 0.001758
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AGZ47548 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSIKTIRRTKVAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSLSLCQSICRCLGKTLDQLFWEEEDEK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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