PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 17-JAN-2021

⊟Summary

• organism: Streptococcus pneumoniae A026
• locus tag: T308_RS07845 [old locus tag: T308_07675 ]
• pan locus tag^?: PNEUPAN003080000
• symbol: T308_RS07845
• pan gene symbol^?: satA
• synonym:
• product: ABC transporter substrate-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: T308_RS07845 [old locus tag: T308_07675 ]
• symbol: T308_RS07845
• product: ABC transporter substrate-binding protein
• replicon: chromosome
• strand: -
• coordinates: 1502685..1504013
• length: 1329
• essential: unknown

⊟Accession numbers

• Location: NC_022655 (1502685..1504013) NCBI
• BioCyc: T308_RS07845 BioCyc
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1495 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  
  ATGAAATTTAGAAAATTAGCTTGTACAGTACTTGCGGGTGCTGCGGTTCTTGGTCTTGCT
  GCTTGTGGCAATTCTGGCGGAAGTAAAGATGCTGCCAAATCAGGTGGTGACGGTGCCAAA
  ACAGAAATCACTTGGTGGGCATTCCCAGTATTTACCCAAGAAAAAACTGGTGACGGTGTT
  GGAACTTATGAAAAATCAATCATCGAAGCGTTTGAAAAAGCAAACCCAGATATAAAAGTG
  AAATTGGAAACCATCGACTTCAAGTCAGGTCCTGAAAAAATCACAACAGCCATCGAAGCA
  GGAACAGCTCCAGACGTACTCTTTGATGCACCAGGACGTATCATCCAATACGGTAAAAAC
  GGTAAATTGGCTGAGTTGAACGACCTCTTCACAGATGAATTTGTTAAAGATGTCAACAAT
  GAAAACATCGTACAAGCAAGTAAAGCTGGAGACAAGGCTTATATGTATCCGATTAGTTCT
  GCCCCATTCTACATGGCAATGAACAAGAAAATGTTAGAAGATGCTGGAGTAGCAAACCTT
  GTAAAAGAAGGTTGGACAACTGATGATTTTGAAAAAGTATTGAAAGCACTTAAAGACAAG
  GGTTACACACCAGGTTCATTGTTCAGTTCTGGTCAAGGGGGAGACCAAGGAACACGTGCC
  TTTATCTCTAACCTTTATAGCGGTTCTGTAACAGATGAAAAAGTTAGCAAATATACAACT
  GATGATCCTAAATTCGTCAAAGGTCTTGAAAAAGCAACTAGCTGGATTAAAGACAATTTG
  ATCAATAATGGTTCACAATTTGACGGTGGGGCAGATATCCAAAACTTTGCCAACGGTCAA
  ACATCTTACACAATCCTTTGGGCACCAGCTCAAAATGGTATCCAAGCTAAACTTTTAGAA
  GCAAGTAAGGTAGAAGTGGTAGAAGTACCATTCCCATCAGACGAAGGTAAGCCAGCTCTT
  GAATATCTTGTAAACGGGTTTGCAGTATTCAACAATAAAGACGACAAGAAAGTCGCTGCA
  TCTAAGAAATTCATCCAGTTTATCGCAGATGACAAGGAGTGGGGACCTAAAGACGTAGTT
  CGTACAGGTGCTTTCCCAGTCCGTACTTCATTTGGAAAACTTTATGAAGACAAACGCATG
  GAAACAATCAGTGGCTGGACTCAATACTACTCACCATACTACAACACTATTGATGGATTT
  GCTGAAATGAGAACACTTTGGTTCCCAATGTTGCAATCTGTATCAAATGGTGACGAAAAA
  CCAGCGGATGCTTTGAAAGCCTTCACTGAAAAAGCAAACGAAACAATCAAAAAAGCTATG
  AAACAATAG
  60
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  240
  300
  360
  420
  480
  540
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  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1329
  

⊟Protein

⊟General

• locus tag: T308_RS07845 [old locus tag: T308_07675 ]
• symbol: T308_RS07845
• description: ABC transporter substrate-binding protein
• length: 442
• theoretical pI: 5.04742
• theoretical MW: 48303.2
• GRAVY: -0.423529

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids carbohydrate ABC transporter substrate-binding protein, CPR_0540 family (TIGR03850; HMM-score: 38.1)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  PBP (CL0177) SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 103.7)
  SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 100.4)
  and 3 more
  SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 16.4)
  LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 11.8)
  no clan defined Ag332; Erythrocyte membrane-associated giant protein antigen 332 (PF04671; HMM-score: 7.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helix: 1
• SignalP: Signal peptide LIPO(Sec/SPII) length 21 aa
  • SP(Sec/SPI): 0.002469
  • TAT(Tat/SPI): 0.000164
  • LIPO(Sec/SPII): 0.997139
  • Cleavage Site: CS pos: 21-22. LAA-CG. Pr: 0.9977
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_000672121 NCBI
• UniProt:

⊟Protein sequence

• MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEITWWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGTAPDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISSAPFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGTRAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNFANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKDDKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSPYYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for TIGR4

⊟Expression data

• PneumoExpress for strain D39V: SPV_1495 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications