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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: SPAT_0571 [new locus tag: EL263_RS03065 ]
  • pan locus tag?: PNEUPAN001547000
  • symbol: tcyJ
  • pan gene symbol?: tcyJ
  • synonym:
  • product: L-cystine-binding protein TcyJ

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAT_0571 [new locus tag: EL263_RS03065 ]
  • symbol: tcyJ
  • product: L-cystine-binding protein TcyJ
  • replicon: chromosome
  • strand: -
  • coordinates: 574230..575030
  • length: 801
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAAAAATTTAGCCTATTACTAGCCATCCTCCCACTTTTAGTTGCCTGTGGAAATCAA
    GCCACACCTAAAGAGACTAACTCTCAAAAGACAATCGTCCTTGCTACAGCTGGCGACGTG
    CCACCATTTGACTACGAAGATAAAGGCAATCTGACAGGCTTCGATATCGAAGTTCTAAAG
    GCAGTAGATGAAAAACTCAGCGACTACGAGATTCAATTTCAAAGAACTGCTTGGGAGAGC
    ATCTTCCCAGGACTTGATTCTGGTCACTATCAGGCTGCGGCCAATAACTTGAGTTACACA
    AAAGAGCGCGCTGAAAGATACCTCTACTCACTTCCGATTTCCAACAATCCCCTCGTCCTC
    GTCAGCAACAAGAAAAATCCTTTGACTTCTCTTGACCAGATCGCTGGTAAAACAACACAA
    GAGGATACCGGAACTTCTAACGCTCAATTCATCAATAACTGGAATCAGAAACACACTGAT
    AATCCCGCTACTATTGATTTTTCTGGTGAGGATATTGGTAAACGAATCCTAGACCTTGCT
    AACGGAGAGTTTGATTTCCTAGTTTTTGACAAGGTATCCGTTCAAAAGATTATCAAGGAC
    CGTGGTTTAGACCTCTCAGTCGTTGATTTACCTTCTGCAGATAGCCCCAGCAATTATATC
    ATTTTCTCAAGCGACCAAAAAGAGTTTAAAGAGAAATTTGATAAAGCGCTCAAAGAACTC
    TATCAAGACGGAACCCTTGAAAAACTCAGCAATACCTATCTAGGTGGTTCTTACCTCCCA
    GATCAATCTCAGTTACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    801

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAT_0571 [new locus tag: EL263_RS03065 ]
  • symbol: TcyJ
  • description: L-cystine-binding protein TcyJ
  • length: 266
  • theoretical pI: 4.49875
  • theoretical MW: 29648
  • GRAVY: -0.456391

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 103.7)
    and 2 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 50.4)
    extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 22.3)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞PFAM:
    PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 155.2)
    and 1 more
    no clan defined DUF4223; Protein of unknown function (DUF4223) (PF13978; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: Signal peptide LIPO(Sec/SPII) length 16 aa
    • SP(Sec/SPI): 0.002035
    • TAT(Tat/SPI): 0.000073
    • LIPO(Sec/SPII): 0.997691
    • Cleavage Site: CS pos: 16-17. LVA-CG. Pr: 0.9981
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG38628 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKFSLLLAILPLLVACGNQATPKETNSQKTIVLATAGDVPPFDYEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKERAERYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTDNPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSNYIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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