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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-APR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS04195 [old locus tag: SP_0856 ]
  • pan locus tag?: PNEUPAN001833000
  • symbol: SP_RS04195
  • pan gene symbol?: ilvE
  • synonym:
  • product: branched-chain amino acid aminotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS04195 [old locus tag: SP_0856 ]
  • symbol: SP_RS04195
  • product: branched-chain amino acid aminotransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 803303..804325
  • length: 1023
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (803303..804325) NCBI
  • BioCyc: SP_RS04195 BioCyc
  • MicrobesOnline: see SP_0856
  • PneumoBrowse for strain D39V: SPV_0749 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGACAGTAACGATTGATTGGGAAAACCTCGGTTTTTCCTATATGAAATTACCTTATCGC
    TATCTTGCTCATTTCAAAAATGGACAATGGGATCAAGGAGAGCTTACAGAGGATGCAACT
    TTGCATATTTCAGAGTCTTCTCCAAGTCTTCACTATGGACAACAAGCATTTGAAGGTTTG
    AAAGCTTATCGTACTAAGGATGGCAGTGTTCAACTGTTCCGTCCTGATGAAAATGCTAAA
    CGTCTGCAACGTACATGTGACCGTCTCTTGATGCCACAAGTTCCGACAGACATGTTTGTA
    GAAGCTTGTAAAGCAGTTGTCCGTGCGAATGAAGAATACGTACCACCATACGGAACAGGT
    GGAACCTTATATCTTCGCCCTCTTTTGATTGGTGTCGGAGATATTATCGGGGTAAAACCG
    GCAGAAGAGTACATTTTCACCATCTTTGCTATGCCAGTTGGAAATTACTTTAAAGGTGGT
    TTGGTCCCAACCAACTTCTTGATTCAGGATGAGTACGACCGTGCAGCACCAAATGGTACA
    GGTGCGGCTAAGGTTGGTGGAAACTATGCTGCAAGTCTCTTACCAGGAAAAATGGCCAAG
    TCACGTCATTTCTCAGATGTTATCTATCTGGACCCATCAACTCATACAAAGATTGAAGAA
    GTCGGATCAGCTAACTTCTTTGGAATTACAGCTGATAATGAATTTGTAACACCATTGAGT
    CCATCTATCTTGCCATCTATTACCAAGTATTCCTTGCTTTATTTGGCAGAACATCGCTTG
    GGATTAACTCCTATTGAGGGTGATGTTCCAATTGATAATCTTGACCGTTTTGTAGAGGCA
    GGTGCCTGTGGTACAGCAGCGGTTATTTCTCCAATTGGAGGTATTCAACATGGTGATGAT
    TTCCATGTATTCTATAGTGAAACAGAAGTAGGTCCTGTGACGCGTAAATTATATAATGAA
    TTGACGGGTATTCAGTTTGGCGATATTGAAGCGCCAGAAGGTTGGATTGTAAAAGTAGAT
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1023

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS04195 [old locus tag: SP_0856 ]
  • symbol: SP_RS04195
  • description: branched-chain amino acid aminotransferase
  • length: 340
  • theoretical pI: 4.72126
  • theoretical MW: 37473.2
  • GRAVY: -0.163824

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 2.6.1.42?  ExPASy
    Branched-chain-amino-acid transaminase L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
  • ⊞TIGRFAM:
    Metabolism Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01123; EC 2.6.1.42; HMM-score: 448.6)
    and 3 more
    Metabolism Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01122; EC 2.6.1.42; HMM-score: 99.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Folic acid aminodeoxychorismate lyase (TIGR03461; EC 4.1.3.38; HMM-score: 16.7)
    Metabolism Energy metabolism Amino acids and amines D-amino-acid transaminase (TIGR01121; EC 2.6.1.21; HMM-score: 14.5)
  • TheSEED: see SP_0856
  • PFAM:
    no clan defined Aminotran_4; Amino-transferase class IV (PF01063; HMM-score: 109.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005728
    • TAT(Tat/SPI): 0.000279
    • LIPO(Sec/SPII): 0.000739
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHISESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEACKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGGLVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKIEEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDRFVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEGWIVKVD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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