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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: ASP0581_15440 [new locus tag: EL334_RS08175 ]
  • symbol: ASP0581_15440
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1529271..1529747
  • length: 477
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGCAAAAGAACCGTGGCAAGAAGATATTTATGATCAAGAAGAATCAAGAGCAGGGCGT
    CGGCATCGAAACCACGGAGGGGCTGATAGGATGGCTAATCGTATTTTGACGATCCTAGCT
    AGTATTTTCTTTGTAATTGTGGTGGTGATGGTCATCGTTCTCATCTATCTATCATCGGGG
    GGGAGTAATCGCACAGCAGCCTTAAAAGACTTTCATGATTCTGATGCAAGTGTAGTACAA
    ATCTCATCTTCAAGCAGTTCTCAGCCTGAGCAGAGTTCAGAGCCAGAATCTACTTCTAGT
    AGTTCAGAAGAAGCTGCTAATCCTGAAGGAACGATTAAAGTTCTCGCAGGAGAAGGGGAA
    GCAGCTATTGCCGCTCGTGCAGGAATCTCCATTGCTCAGTTAGAGGCCTTGAATCCTGGG
    CACATGGCTACAGGATCTTGGTTTGCTAATCCAGGTGATGTTATAAAAATAAAATAG
    60
    120
    180
    240
    300
    360
    420
    477

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: ASP0581_15440 [new locus tag: EL334_RS08175 ]
  • symbol: ASP0581_15440
  • description: hypothetical protein
  • length: 158
  • theoretical pI: 4.78786
  • theoretical MW: 16797.6
  • GRAVY: -0.189873

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus protein PrgH/EprH (TIGR02554; HMM-score: 14.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus protein PrgH/EprH (TIGR02554; HMM-score: 14.9)
    variant surface antigen, rifin family (TIGR01477; HMM-score: 13.1)
    and 1 more
    Metabolism Transport and binding proteins Other Niemann-Pick C type protein family (TIGR00917; HMM-score: 10.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined SecG; Preprotein translocase SecG subunit (PF03840; HMM-score: 16.7)
    DUF1673; Protein of unknown function (DUF1673) (PF07895; HMM-score: 16)
    MSP1a; Major surface protein 1a (MSP1a) (PF11670; HMM-score: 15.3)
    VSA (CL0656) RIFIN; Rifin (PF02009; HMM-score: 14.8)
    no clan defined DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 14.7)
    LysM (CL0187) LysM; LysM domain (PF01476; HMM-score: 14.3)
    no clan defined ODV-E18; Occlusion-derived virus envelope protein ODV-E18 (PF10717; HMM-score: 14.3)
    Viral_Beta_CD; Viral Beta C/D like family (PF04530; HMM-score: 13.9)
    and 7 more
    MRAP; Melanocortin-2 receptor accessory protein family (PF15183; HMM-score: 12.6)
    Orf78; Orf78 (ac78) (PF06024; HMM-score: 12)
    OB (CL0021) tRNA_anti-like; tRNA_anti-like (PF12869; HMM-score: 12)
    no clan defined Shisa; Wnt and FGF inhibitory regulator (PF13908; HMM-score: 11.9)
    ASFV_J13L; African swine fever virus J13L protein (PF05568; HMM-score: 11.7)
    SCAI; Protein SCAI (PF12070; HMM-score: 11.3)
    4HB_MCP (CL0457) TarH; Tar ligand binding domain homologue (PF02203; HMM-score: 11.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001714
    • TAT(Tat/SPI): 0.000249
    • LIPO(Sec/SPII): 0.00105
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG82066 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFFVIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSSEEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

NCBI: 03-SEP-2019

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: ASP0581_15440 [new locus tag: EL334_RS08175 ]
  • pan locus tag?: PNEUPAN002993000
  • symbol: ASP0581_15440
  • pan gene symbol?: rpsO_1
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: ASP0581_15440 [new locus tag: EL334_RS08175 ]
  • symbol: ASP0581_15440
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1529271..1529747
  • length: 477
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGCAAAAGAACCGTGGCAAGAAGATATTTATGATCAAGAAGAATCAAGAGCAGGGCGT
    CGGCATCGAAACCACGGAGGGGCTGATAGGATGGCTAATCGTATTTTGACGATCCTAGCT
    AGTATTTTCTTTGTAATTGTGGTGGTGATGGTCATCGTTCTCATCTATCTATCATCGGGG
    GGGAGTAATCGCACAGCAGCCTTAAAAGACTTTCATGATTCTGATGCAAGTGTAGTACAA
    ATCTCATCTTCAAGCAGTTCTCAGCCTGAGCAGAGTTCAGAGCCAGAATCTACTTCTAGT
    AGTTCAGAAGAAGCTGCTAATCCTGAAGGAACGATTAAAGTTCTCGCAGGAGAAGGGGAA
    GCAGCTATTGCCGCTCGTGCAGGAATCTCCATTGCTCAGTTAGAGGCCTTGAATCCTGGG
    CACATGGCTACAGGATCTTGGTTTGCTAATCCAGGTGATGTTATAAAAATAAAATAG
    60
    120
    180
    240
    300
    360
    420
    477

This data comes from external databases and cannot be edited.

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: ASP0581_15440 [new locus tag: EL334_RS08175 ]
  • symbol: ASP0581_15440
  • description: hypothetical protein
  • length: 158
  • theoretical pI: 4.78786
  • theoretical MW: 16797.6
  • GRAVY: -0.189873

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus protein PrgH/EprH (TIGR02554; HMM-score: 14.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus protein PrgH/EprH (TIGR02554; HMM-score: 14.9)
    variant surface antigen, rifin family (TIGR01477; HMM-score: 13.1)
    and 1 more
    Metabolism Transport and binding proteins Other Niemann-Pick C type protein family (TIGR00917; HMM-score: 10.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined SecG; Preprotein translocase SecG subunit (PF03840; HMM-score: 16.7)
    DUF1673; Protein of unknown function (DUF1673) (PF07895; HMM-score: 16)
    MSP1a; Major surface protein 1a (MSP1a) (PF11670; HMM-score: 15.3)
    VSA (CL0656) RIFIN; Rifin (PF02009; HMM-score: 14.8)
    no clan defined DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 14.7)
    LysM (CL0187) LysM; LysM domain (PF01476; HMM-score: 14.3)
    no clan defined ODV-E18; Occlusion-derived virus envelope protein ODV-E18 (PF10717; HMM-score: 14.3)
    Viral_Beta_CD; Viral Beta C/D like family (PF04530; HMM-score: 13.9)
    and 7 more
    MRAP; Melanocortin-2 receptor accessory protein family (PF15183; HMM-score: 12.6)
    Orf78; Orf78 (ac78) (PF06024; HMM-score: 12)
    OB (CL0021) tRNA_anti-like; tRNA_anti-like (PF12869; HMM-score: 12)
    no clan defined Shisa; Wnt and FGF inhibitory regulator (PF13908; HMM-score: 11.9)
    ASFV_J13L; African swine fever virus J13L protein (PF05568; HMM-score: 11.7)
    SCAI; Protein SCAI (PF12070; HMM-score: 11.3)
    4HB_MCP (CL0457) TarH; Tar ligand binding domain homologue (PF02203; HMM-score: 11.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001714
    • TAT(Tat/SPI): 0.000249
    • LIPO(Sec/SPII): 0.00105
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG82066 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFFVIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSSEEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

Other Information[edit | edit source]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]