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serotype 4
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serotype 19A
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serotype 6B
6A-10
serotype 6A
70585
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A026
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A66
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AP200
serotype 11A
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BVJ1JL
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CGSP14
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
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INV200
serotype 14
JJA
serotype 14
MDRSPN001
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NCTC7466
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NU83127
serotype 4
OXC141
serotype 3
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R6
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SP49
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SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC10590 [new locus tag: SPNOXC_RS05710 ]
  • pan locus tag?: PNEUPAN002444000
  • symbol: nrdH
  • pan gene symbol?: nrdH
  • synonym:
  • product: glutaredoxin-like protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC10590 [new locus tag: SPNOXC_RS05710 ]
  • symbol: nrdH
  • product: glutaredoxin-like protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1084051..1084269
  • length: 219
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGGTAACCGTTTATTCTAAAAACAATTGTGTCCAATGTAAAATGACCAAGCGTTTCTTG
    GACAGTAATAATGTCTCTTATCGTGAAATCAATCTTGATGAGCAACCTGAGTACGTCGAT
    CAAGTTAAAGAGCTCGGTTTTAGCGCAGCTCCTGTTATCCAAACACCAACTGAAGTCTTT
    TCAGGTTTCCAACCAGGAAAACTGAAACAATTAGCATAA
    60
    120
    180
    219

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC10590 [new locus tag: SPNOXC_RS05710 ]
  • symbol: NrdH
  • description: glutaredoxin-like protein
  • length: 72
  • theoretical pI: 6.49891
  • theoretical MW: 8174.28
  • GRAVY: -0.419444

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    glutaredoxin-like protein NrdH (TIGR02194; HMM-score: 116)
    and 7 more
    glutaredoxin-like protein, YruB-family (TIGR02196; HMM-score: 58.5)
    Metabolism Energy metabolism Electron transport glutaredoxin 3 (TIGR02181; HMM-score: 32.3)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, Spx/MgsR family (TIGR01617; HMM-score: 31.2)
    glutaredoxin-like protein (TIGR02200; HMM-score: 29.3)
    glutaredoxin (TIGR02180; HMM-score: 21.3)
    glutaredoxin-family domain (TIGR02190; HMM-score: 19)
    glutaredoxin-like family (TIGR02189; HMM-score: 12.4)
  • ⊞TheSEED  :
    • Glutaredoxin-like protein NrdH, associated with reduction of ribonucleotide reductase class Ib
    Nucleosides and Nucleotides Nucleosides and Nucleotides - no subcategory Ribonucleotide reduction  Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
    and 2 more
    Stress Response Oxidative stress Glutaredoxins  Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
    Stress Response Oxidative stress Glutathione: Redox cycle  Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
  • PFAM:
    Thioredoxin (CL0172) Glutaredoxin; Glutaredoxin (PF00462; HMM-score: 55)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004551
    • TAT(Tat/SPI): 0.000211
    • LIPO(Sec/SPII): 0.001043
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32715 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKELGFSAAPVIQTPTEVFSGFQPGKLKQLA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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