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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-FEB-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS06095 [old locus tag: SPAP_1232 ]
  • pan locus tag?: PNEUPAN002490000
  • symbol: SPAP_RS06095
  • pan gene symbol?: xseB
  • synonym:
  • product: exodeoxyribonuclease VII small subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS06095 [old locus tag: SPAP_1232 ]
  • symbol: SPAP_RS06095
  • product: exodeoxyribonuclease VII small subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1169186..1169398
  • length: 213
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014494 (1169186..1169398) NCBI
  • BioCyc: SPAP_RS06095 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1066 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGTCAAAACAAAAGAAATTTGAGGAAAATCTAGCAGAACTGGAAACCATTGTCCAAAGT
    TTGGAAAATGGTGAAATTGATCTGGAAGATGCGATTACTGCCTTTCAAAAGGGCATGGTC
    TTGTCAAAAGAGCTCCAAGCTACGCTGGACAAGGCTGAAAAGACCTTGGTCAAGGTCATG
    CAAGAAGACGGAACAGAAAGTGATTTTGAATGA
    60
    120
    180
    213

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_RS06095 [old locus tag: SPAP_1232 ]
  • symbol: SPAP_RS06095
  • description: exodeoxyribonuclease VII small subunit
  • length: 70
  • theoretical pI: 4.01831
  • theoretical MW: 7893.83
  • GRAVY: -0.561429

⊟Function[edit | edit source]

  • ⊞⊞reaction:
    EC 3.1.11.6?  ExPASy
    Exodeoxyribonuclease VII Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates
  • TIGRFAM:
    Genetic information processing DNA metabolism Degradation of DNA exodeoxyribonuclease VII, small subunit (TIGR01280; EC 3.1.11.6; HMM-score: 73.6)
  • TheSEED: see SPAP_1232
  • ⊞⊞PFAM:
    no clan defined Exonuc_VII_S; Exonuclease VII small subunit (PF02609; HMM-score: 67.7)
    and 5 more
    Trimer_CC; Trimerisation motif (PF08954; HMM-score: 15.4)
    DUF6687; Family of unknown function (DUF6687) (PF20392; HMM-score: 13.7)
    KxDL; Uncharacterized conserved protein (PF10241; HMM-score: 13.2)
    Syntaxin-6_N; Syntaxin 6, N-terminal (PF09177; HMM-score: 12.9)
    DUF3323; Protein of unknown function N-terminus (DUF3323) (PF11796; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002159
    • TAT(Tat/SPI): 0.000379
    • LIPO(Sec/SPII): 0.000267
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000043231 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKQKKFEENLAELETIVQSLENGEIDLEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPAP_RS06095&oldid=41184"
Insert paragraph

NCBI: 22-FEB-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS06095 [old locus tag: SPAP_1232 ]
  • pan locus tag?: PNEUPAN002490000
  • symbol: SPAP_RS06095
  • pan gene symbol?: xseB
  • synonym:
  • product: exodeoxyribonuclease VII small subunit

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS06095 [old locus tag: SPAP_1232 ]
  • symbol: SPAP_RS06095
  • product: exodeoxyribonuclease VII small subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1169186..1169398
  • length: 213
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: NC_014494 (1169186..1169398) NCBI
  • BioCyc: SPAP_RS06095 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1066 PneumoBrowse

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGTCAAAACAAAAGAAATTTGAGGAAAATCTAGCAGAACTGGAAACCATTGTCCAAAGT
    TTGGAAAATGGTGAAATTGATCTGGAAGATGCGATTACTGCCTTTCAAAAGGGCATGGTC
    TTGTCAAAAGAGCTCCAAGCTACGCTGGACAAGGCTGAAAAGACCTTGGTCAAGGTCATG
    CAAGAAGACGGAACAGAAAGTGATTTTGAATGA
    60
    120
    180
    213

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_RS06095 [old locus tag: SPAP_1232 ]
  • symbol: SPAP_RS06095
  • description: exodeoxyribonuclease VII small subunit
  • length: 70
  • theoretical pI: 4.01831
  • theoretical MW: 7893.83
  • GRAVY: -0.561429

Insert paragraph

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 3.1.11.6?  ExPASy
    Exodeoxyribonuclease VII Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates
  • TIGRFAM:
    Genetic information processing DNA metabolism Degradation of DNA exodeoxyribonuclease VII, small subunit (TIGR01280; EC 3.1.11.6; HMM-score: 73.6)
  • TheSEED: see SPAP_1232
  • ⊞PFAM:
    no clan defined Exonuc_VII_S; Exonuclease VII small subunit (PF02609; HMM-score: 67.7)
    and 5 more
    Trimer_CC; Trimerisation motif (PF08954; HMM-score: 15.4)
    DUF6687; Family of unknown function (DUF6687) (PF20392; HMM-score: 13.7)
    KxDL; Uncharacterized conserved protein (PF10241; HMM-score: 13.2)
    Syntaxin-6_N; Syntaxin 6, N-terminal (PF09177; HMM-score: 12.9)
    DUF3323; Protein of unknown function N-terminus (DUF3323) (PF11796; HMM-score: 12.6)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002159
    • TAT(Tat/SPI): 0.000379
    • LIPO(Sec/SPII): 0.000267
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000043231 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MSKQKKFEENLAELETIVQSLENGEIDLEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

  • regulator:

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph