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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 20-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC_RS08150 [old locus tags: SPNOXC15070 SPNOXC_15070 ]
  • pan locus tag?: PNEUPAN003117000
  • symbol: nrdR
  • pan gene symbol?: nrdR
  • synonym:
  • product: transcriptional regulator NrdR

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC_RS08150 [old locus tags: SPNOXC15070 SPNOXC_15070 ]
  • symbol: nrdR
  • product: transcriptional regulator NrdR
  • replicon: chromosome
  • strand: -
  • coordinates: 1533696..1534169
  • length: 474
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017592 (1533696..1534169) NCBI
  • BioCyc: SPNOXC_RS08150 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1523 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCGTTGTCCAAAATGTGGGGCTACCAAGTCAAGTGTTATCGATAGTCGCCAAGCAGAA
    GAAGGGAACACCATTCGTAGAAGACGAGAGTGCGGCGAGTGCCAACACCGTTTTACAACC
    TACGAACGAGTAGAAGAAAGAACCTTAGTGGTTGTTAAAAAAGATGGCACACGGGAACAA
    TTCTCCAGAGATAAAATCTTTAATGGGATTATCCGCTCAGCCCAGAAACGTCCTGTGTCA
    AGTGATGAAATCAACATGGTAGTCAATCGTATCGAACAGAAACTCCGTGGTCGAAATGAA
    AATGAAATTCAAAGTGAGGACATTGGTTCACTCGTCATGGAGGAGTTGGCTGAATTGGAC
    GAGATTACCTATGTACGTTTTGCTAGTGTCTATCGTAGTTTTAAGGATGTCAGTGAGTTA
    GAGAGCTTGCTCCAACAAATCACCCAGTCCTCTAAAAAGAAAAAGGAAAGATAA
    60
    120
    180
    240
    300
    360
    420
    474

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC_RS08150 [old locus tags: SPNOXC15070 SPNOXC_15070 ]
  • symbol: NrdR
  • description: transcriptional regulator NrdR
  • length: 157
  • theoretical pI: 8.94657
  • theoretical MW: 18321.6
  • GRAVY: -0.898089

⊟Function[edit | edit source]

  • ⊞⊞TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator NrdR (TIGR00244; HMM-score: 190.7)
    and 4 more
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions restriction alleviation protein, Lar family (TIGR03655; HMM-score: 15.5)
    Genetic information processing DNA metabolism Restriction/modification restriction alleviation protein, Lar family (TIGR03655; HMM-score: 15.5)
    Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 13.8)
    MJ0042 family finger-like domain (TIGR02098; HMM-score: 9.3)
  • TheSEED: see SPNOXC15070
  • ⊞⊞PFAM:
    no clan defined ATP-cone; ATP cone domain (PF03477; HMM-score: 73.6)
    and 8 more
    Zn_Beta_Ribbon (CL0167) TFIIS_C; Transcription factor S-II (TFIIS) (PF01096; HMM-score: 20.1)
    Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 18.8)
    POTRA (CL0191) POTRA_2; POTRA domain, ShlB-type (PF08479; HMM-score: 13.8)
    no clan defined DUF3223; Protein of unknown function (DUF3223) (PF11523; HMM-score: 13.6)
    Zn_Beta_Ribbon (CL0167) Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 12.8)
    TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 11.9)
    zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 11)
    zinc_ribbon_4; zinc-ribbon domain (PF13717; HMM-score: 8.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by NrdR*, TF important in Deoxyribonucleotide biosynthesis: in TIGR4

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02476
    • TAT(Tat/SPI): 0.001481
    • LIPO(Sec/SPII): 0.007943
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001203675 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRCPKCGATKSSVIDSRQAEEGNTIRRRRECGECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNOXC_RS08150&oldid=119601"
Insert paragraph

NCBI: 20-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC_RS08150 [old locus tags: SPNOXC15070 SPNOXC_15070 ]
  • pan locus tag?: PNEUPAN003117000
  • symbol: nrdR
  • pan gene symbol?: nrdR
  • synonym:
  • product: transcriptional regulator NrdR

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC_RS08150 [old locus tags: SPNOXC15070 SPNOXC_15070 ]
  • symbol: nrdR
  • product: transcriptional regulator NrdR
  • replicon: chromosome
  • strand: -
  • coordinates: 1533696..1534169
  • length: 474
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: NC_017592 (1533696..1534169) NCBI
  • BioCyc: SPNOXC_RS08150 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1523 PneumoBrowse

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCGTTGTCCAAAATGTGGGGCTACCAAGTCAAGTGTTATCGATAGTCGCCAAGCAGAA
    GAAGGGAACACCATTCGTAGAAGACGAGAGTGCGGCGAGTGCCAACACCGTTTTACAACC
    TACGAACGAGTAGAAGAAAGAACCTTAGTGGTTGTTAAAAAAGATGGCACACGGGAACAA
    TTCTCCAGAGATAAAATCTTTAATGGGATTATCCGCTCAGCCCAGAAACGTCCTGTGTCA
    AGTGATGAAATCAACATGGTAGTCAATCGTATCGAACAGAAACTCCGTGGTCGAAATGAA
    AATGAAATTCAAAGTGAGGACATTGGTTCACTCGTCATGGAGGAGTTGGCTGAATTGGAC
    GAGATTACCTATGTACGTTTTGCTAGTGTCTATCGTAGTTTTAAGGATGTCAGTGAGTTA
    GAGAGCTTGCTCCAACAAATCACCCAGTCCTCTAAAAAGAAAAAGGAAAGATAA
    60
    120
    180
    240
    300
    360
    420
    474

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC_RS08150 [old locus tags: SPNOXC15070 SPNOXC_15070 ]
  • symbol: NrdR
  • description: transcriptional regulator NrdR
  • length: 157
  • theoretical pI: 8.94657
  • theoretical MW: 18321.6
  • GRAVY: -0.898089

Insert paragraph

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator NrdR (TIGR00244; HMM-score: 190.7)
    and 4 more
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions restriction alleviation protein, Lar family (TIGR03655; HMM-score: 15.5)
    Genetic information processing DNA metabolism Restriction/modification restriction alleviation protein, Lar family (TIGR03655; HMM-score: 15.5)
    Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 13.8)
    MJ0042 family finger-like domain (TIGR02098; HMM-score: 9.3)
  • TheSEED: see SPNOXC15070
  • ⊞PFAM:
    no clan defined ATP-cone; ATP cone domain (PF03477; HMM-score: 73.6)
    and 8 more
    Zn_Beta_Ribbon (CL0167) TFIIS_C; Transcription factor S-II (TFIIS) (PF01096; HMM-score: 20.1)
    Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 18.8)
    POTRA (CL0191) POTRA_2; POTRA domain, ShlB-type (PF08479; HMM-score: 13.8)
    no clan defined DUF3223; Protein of unknown function (DUF3223) (PF11523; HMM-score: 13.6)
    Zn_Beta_Ribbon (CL0167) Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 12.8)
    TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 11.9)
    zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 11)
    zinc_ribbon_4; zinc-ribbon domain (PF13717; HMM-score: 8.5)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by NrdR*, TF important in Deoxyribonucleotide biosynthesis: in TIGR4

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02476
    • TAT(Tat/SPI): 0.001481
    • LIPO(Sec/SPII): 0.007943
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001203675 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MRCPKCGATKSSVIDSRQAEEGNTIRRRRECGECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

  • regulator:

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph