From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_RS11900
  • symbol: CXP32_RS11900
  • product: HAD-IB family phosphatase
  • replicon: chromosome
  • strand: +
  • coordinates: 1059397..1059768
  • length: 372
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_CP025256 (1059397..1059768) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1009 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTCTCAAGTAAAAGGCTTGTGTGTTTTGGATGTAGATGGAACCTTAATCCTAGAAGAA
    GTGATTGATCTTTTAGGGAGAGAGGCAGGTCATGAGGCGGAAATTTCGCAGATTACAAGT
    CGAGCAATGCGAGGAGAGTTGGTCTTTGAAAGCAGTTTAAGAAAAAGAGTGTCCTTGTTG
    GAAGGTCTTCCTATTTTGGTCTTTGATAACGTCTTCAACTCAATTCATCTATCGCTAAAT
    GTCCCAGAGTTCATCTCTATTCTCCAAAAGAATGGCATCCTAGTTGGTCTGGTGTCTGGT
    GGATTTACACCAATAGTTGGAGAGATTAGCAAAATCCCTTGGTATTGCCTATTTCACTGC
    CAACTAGCTTGA
    60
    120
    180
    240
    300
    360
    372

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: CXP32_RS11900
  • symbol: CXP32_RS11900
  • description: HAD-IB family phosphatase
  • length: 123
  • theoretical pI: 4.82575
  • theoretical MW: 13506.7
  • GRAVY: 0.514634

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 105.8)
    and 5 more
    Unknown function Enzymes of unknown specificity HAD phosphoserine phosphatase-like hydrolase, family IB (TIGR01488; HMM-score: 53.1)
    phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 19.4)
    HAD phosphatase, family IIIC (TIGR01681; HMM-score: 15.4)
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 12.6)
    Metabolism Central intermediary metabolism Other 2,3-diketo-5-methylthio-1-phosphopentane phosphatase (TIGR01489; HMM-score: 11.8)
  • TheSEED:
  • PFAM:
    HAD (CL0137) HAD; haloacid dehalogenase-like hydrolase (PF12710; HMM-score: 31.7)
    and 1 more
    Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 16.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001538
    • TAT(Tat/SPI): 0.000094
    • LIPO(Sec/SPII): 0.000175
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001808482 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMRGELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGFTPIVGEISKIPWYCLFHCQLA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

NCBI: 17-FEB-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Xen35
  • locus tag: CXP32_RS11900
  • pan locus tag?: PNEUPAN002272000
  • symbol: CXP32_RS11900
  • pan gene symbol?: serB
  • synonym:
  • product: HAD-IB family phosphatase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_RS11900
  • symbol: CXP32_RS11900
  • product: HAD-IB family phosphatase
  • replicon: chromosome
  • strand: +
  • coordinates: 1059397..1059768
  • length: 372
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_CP025256 (1059397..1059768) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1009 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTCTCAAGTAAAAGGCTTGTGTGTTTTGGATGTAGATGGAACCTTAATCCTAGAAGAA
    GTGATTGATCTTTTAGGGAGAGAGGCAGGTCATGAGGCGGAAATTTCGCAGATTACAAGT
    CGAGCAATGCGAGGAGAGTTGGTCTTTGAAAGCAGTTTAAGAAAAAGAGTGTCCTTGTTG
    GAAGGTCTTCCTATTTTGGTCTTTGATAACGTCTTCAACTCAATTCATCTATCGCTAAAT
    GTCCCAGAGTTCATCTCTATTCTCCAAAAGAATGGCATCCTAGTTGGTCTGGTGTCTGGT
    GGATTTACACCAATAGTTGGAGAGATTAGCAAAATCCCTTGGTATTGCCTATTTCACTGC
    CAACTAGCTTGA
    60
    120
    180
    240
    300
    360
    372

This data comes from external databases and cannot be edited.

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: CXP32_RS11900
  • symbol: CXP32_RS11900
  • description: HAD-IB family phosphatase
  • length: 123
  • theoretical pI: 4.82575
  • theoretical MW: 13506.7
  • GRAVY: 0.514634

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 105.8)
    and 5 more
    Unknown function Enzymes of unknown specificity HAD phosphoserine phosphatase-like hydrolase, family IB (TIGR01488; HMM-score: 53.1)
    phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 19.4)
    HAD phosphatase, family IIIC (TIGR01681; HMM-score: 15.4)
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 12.6)
    Metabolism Central intermediary metabolism Other 2,3-diketo-5-methylthio-1-phosphopentane phosphatase (TIGR01489; HMM-score: 11.8)
  • TheSEED:
  • PFAM:
    HAD (CL0137) HAD; haloacid dehalogenase-like hydrolase (PF12710; HMM-score: 31.7)
    and 1 more
    Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 16.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001538
    • TAT(Tat/SPI): 0.000094
    • LIPO(Sec/SPII): 0.000175
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001808482 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMRGELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGFTPIVGEISKIPWYCLFHCQLA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

Other Information[edit | edit source]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]