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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr0228 [new locus tag: SPR_RS01195 ]
  • pan locus tag?: PNEUPAN000980000
  • symbol: spr0228
  • pan gene symbol?: sorC_2
  • synonym:
  • product: Conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr0228 [new locus tag: SPR_RS01195 ]
  • symbol: spr0228
  • product: Conserved hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 219268..220248
  • length: 981
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAATCAAGATAGGAATAAACTGCTCTCTAAAATTGCTTATCTGTATTATATTGAAAAC
    TTAAATCAGTCACAAATAGCAGCAAAATTAGGAATTTATAGAACCTCTATTAGTAGAATG
    TTAACAGAAGCAAGGAATGCAGGAATTGTTAAAATTGAAATAGAGAATTTTGATACCAAT
    ATGTTTAAGTTGGAAAATTATGTAAAAGAAAAATATGGTCTGGAAAGTTTAGAAATTATT
    CCAAATGAATTTGATGATAATCCAACAATTTTATCTGAAAGAATTTCTCAAGTTGCAGCA
    GGTGTCCTTAGGAATCTAATTGATGATAATATGAAAATTGGCTTTTCTTGGGGGAAAAGT
    TTAAGTAATTTAGTAGATTTAATTCACAGTAAAAGTGTCCGAAATGTTCACTTCTATCCT
    CTAGCAGGTGGTCCTAGTCACATACACGCTAAATACCATGTGAATACACTGATTTATGAA
    ATGTCTAGAAAATTTCATGGAGAGTGTACATTTATGAATGCAACGATTGTGCAAGAAAAT
    AAATTGTTAGCAGATGGTATTTTGCAATCAAGATATTTTGAAAATTTGAAAAATAGTTGG
    AAAGATTTAGATATAGCTGTAGTCGGAATTGGTGATTTTAGCAATAAAGGAAAGCATCAA
    TGGTTAGACATGCTTACAGAGGATGACTTTAAAGAATTGACCAAAGTTAAAACTGTAGGA
    GAAATTTGTTGTCGATTTTTTGATTCAAAAGGTAAAGAAGTCTATGAAAACTTACAGGAA
    AGAACGATAGCAATCTCTTTGGAAGATTTAAAAAATATTCCTCAAAGTTTAGCTGTTGCT
    TACGGTGATACGAAAGTATCTTCGATTCTTTCTGTCTTGCGTGCTAATTTAGTAAATCAT
    TTGATTACAGACAAAAATACAATTTTAAAAGTTTTGGAAGAAGATGGGGATTTGACTTTT
    AGAGAGATTCTAGGTGAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    981

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr0228 [new locus tag: SPR_RS01195 ]
  • symbol: spr0228
  • description: Conserved hypothetical protein
  • length: 326
  • theoretical pI: 6.1174
  • theoretical MW: 37192.3
  • GRAVY: -0.268405

⊟Function[edit | edit source]

  • TIGRFAM:
    RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 20.8)
    RNA polymerase sigma-70 factor, sigma-B/F/G subfamily (TIGR02980; HMM-score: 17.4)
    and 1 more
    EPS-associated transcriptional regulator, MarR family (TIGR04176; HMM-score: 13.1)
  • TheSEED  :
    • Transcriptional regulator, DeoR family
  • PFAM:
    ISOCOT_Fold (CL0246) Sugar-bind; Putative sugar-binding domain (PF04198; HMM-score: 278.1)
    and 16 more
    HTH (CL0123) HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 27.5)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 21.7)
    MarR_2; MarR family (PF12802; HMM-score: 19.1)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 18.5)
    MarR; MarR family (PF01047; HMM-score: 17.1)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 16)
    Cro; Cro (PF09048; HMM-score: 15.9)
    HTH_37; Helix-turn-helix domain (PF13744; HMM-score: 14.5)
    HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 13.9)
    KORA; TrfB plasmid transcriptional repressor (PF16509; HMM-score: 13.9)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 13.8)
    Phosphatase (CL0031) NleF_casp_inhib; NleF caspase inhibitor (PF16809; HMM-score: 13.6)
    HTH (CL0123) HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 13.3)
    HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 12.9)
    no clan defined SFXNs; Sideroflexins (PF03820; HMM-score: 12.1)
    HTH (CL0123) Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9457
    • Cytoplasmic Membrane Score: 0.0259
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0281
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003801
    • TAT(Tat/SPI): 0.00077
    • LIPO(Sec/SPII): 0.0004
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEARNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGVLRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYEMSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGKHQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQSLAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: DeoR/PflR (repression) regulon
    DeoR/PflR(TF)important in Formate metabolism; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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