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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 30-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae R6
- locus tag: spr0861 [new locus tag: SPR_RS04320 ]
- pan locus tag?: PNEUPAN001956000
- symbol: infC
- pan gene symbol?: infC
- synonym:
- product: Translation initiation factor IF-3
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: spr0861 [new locus tag: SPR_RS04320 ]
- symbol: infC
- product: Translation initiation factor IF-3
- replicon: chromosome
- strand: +
- coordinates: 855261..855848
- length: 588
- essential: yes [1] DEG other strains
⊟Accession numbers[edit | edit source]
- Location: AE007317 (855261..855848) NCBI
- BioCyc: SPR0861 BioCyc
- MicrobesOnline: 133746 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0847 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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481
541GTGCGGGCTTGTATATTTACGAGTCCGCTATTGTTTTTCTCTAATAAAACAAAAGAGGTG
AAAACCATAGCAAAGCAAGACTTATTCATCAATGATGAGATTCGTGTACGTGAAGTTCGC
TTGATTGGTCTTGAGGGAGAACAGCTAGGCATCAAGCCACTCAGTGAAGCGCAAGCTTTG
GCTGATAACGCTAATGTTGACCTAGTATTGATTCAACCCCAAGCCAAACCGCCTGTTGCA
AAAATTATGGACTACGGTAAGTTCAAATTTGAGTACCAGAAGAAGCAAAAAGAACAACGT
AAAAAACAAAGCGTTGTTACTGTGAAAGAAGTTCGTCTAAGTCCAACTATTGACAAGGGT
GACTTTGATACAAAACTTCGTAATGCACGTAAGTTCCTTGAAAAAGGAAATAAAGTTAAG
GTATCTATTCGCTTTAAGGGTCGTATGATTACCCATAAAGAGATTGGTGCAAAAGTTTTA
GCCGAGTTTGCTGAAGCAACTCAAGATATTGCCATCATCGAACAACGTGCTAAAATGGAT
GGACGTCAAATGTTCATGCAATTGGCGCCAGCGACTGACAAAAAATAA60
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588
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: spr0861 [new locus tag: SPR_RS04320 ]
- symbol: InfC
- description: Translation initiation factor IF-3
- length: 195
- theoretical pI: 10.5939
- theoretical MW: 22267
- GRAVY: -0.464615
⊟Function[edit | edit source]
- TIGRFAM: Protein synthesis Translation factors translation initiation factor IF-3 (TIGR00168; HMM-score: 214.7)
- TheSEED :
- Translation initiation factor 3
Protein Metabolism Protein biosynthesis Translation initiation factors bacterial Translation initiation factor 3and 1 more - PFAM: no clan defined IF3_C; Translation initiation factor IF-3, C-terminal domain (PF00707; HMM-score: 122.5)IF3_N; Translation initiation factor IF-3, N-terminal domain (PF05198; HMM-score: 98.9)and 1 morePolo-box (CL0708) Polo_box_3; Polo box domain (PF18544; HMM-score: 15.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9851
- Cytoplasmic Membrane Score: 0.0013
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0134
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.028408
- TAT(Tat/SPI): 0.000604
- LIPO(Sec/SPII): 0.002019
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MRACIFTSPLLFFSNKTKEVKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADNANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGDFDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKMDGRQMFMQLAPATDKK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: infC > rpmI > rplT > lguL
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0847 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
Nucleic Acids Res: 2002, 30(14);3152-62
[PubMed:12136097] [WorldCat.org] [DOI] (I p)