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serotype 3
SPN034183
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SPN994038
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TCH8431/19A
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serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr1711 [new locus tag: SPR_RS08510 ]
  • pan locus tag?: PNEUPAN003394000
  • symbol: msmF
  • pan gene symbol?: msmF
  • synonym:
  • product: ABC transporter membrane-spanning permease - multiple sugars

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr1711 [new locus tag: SPR_RS08510 ]
  • symbol: msmF
  • product: ABC transporter membrane-spanning permease - multiple sugars
  • replicon: chromosome
  • strand: -
  • coordinates: 1683638..1684528
  • length: 891
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGTGGATTAGGAGTAGAGAGACTATGAAAAAAGTATTACAAAAATATTGGGCATGGGCT
    TTTGTGGTCATCCCCCTCTTGTTACAAGCAATTTTCTTCTATGTGCCGATGTTTCAAGGA
    GCCTTTTACAGTTTTACCAACTGGACAGGATTGACTTATAACTACAAATTTGTCGGCTTA
    AACAACTTTAAGCTCCTCTTCATGGATCCAAAATTCATGAATGCGATTGGCTTTACCGCA
    ATCATTACGATTGCCATGGTGGTTGGTGAGATTGCACTCGGGATCTTCATTGCGCGTGTC
    TTGAACTCTAAAATCAAAGGCCAAACCTTCTTCCGTTCTTGGTTCTTCTTCCCAGCTGTT
    TTATCTGGTTTGACAGTGGCTTTGATCTTCAAGCAAGTCTTCAACTACGGTCTTCCAGCG
    ATTGGGAATGCCCTTCATATTGAATTTCTCCAAACCAGTCTTTTAGGGACTAAGTGGGGA
    GCAATCTTTGCGGCTGTCTTTGTCCTTCTTTGGCAAGGGGTGGCTATGCCCATCATCATC
    TTCCTAGCTGGTTTGCAATCTATTCCAACTGAGATTACAGAGGCAGCAAGGATTGATGGT
    GCGACTAGCAAGCAAGTTTTCTGGAACATTGAATTGCCTTACTTGCTACCAAGTGTCTCT
    ATAGTCTTTATCCTAGCCCTAAAAGGTGGGCTGACTGCCTTTGACCAAGTCTTTGCCATG
    ACCGGTGGTGGTCCAAACAATGCCACAACCTCACTTGGGCTCTTGGTTTATAACTATGCC
    TTTAAAAACAACCAATTCGGTTATGCCAATGCCATTGCCGTAATCTTGTTCTTCTTAATT
    GTAGTGATTTCGATCATCCAATTGAGAGTATCTAAGAAATTTGAAATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    891

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr1711 [new locus tag: SPR_RS08510 ]
  • symbol: MsmF
  • description: ABC transporter membrane-spanning permease - multiple sugars
  • length: 296
  • theoretical pI: 10.3206
  • theoretical MW: 33167.3
  • GRAVY: 0.8

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 40.2)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 38.7)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 35.5)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 32.3)
    and 2 more
    choline ABC transporter, permease protein (TIGR03416; HMM-score: 26.8)
    integral membrane protein (TIGR04561; HMM-score: 8.3)
  • TheSEED  :
    • Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
    Carbohydrates Di- and oligosaccharides Fructooligosaccharides(FOS) and Raffinose Utilization  Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 62.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.036778
    • TAT(Tat/SPI): 0.000652
    • LIPO(Sec/SPII): 0.022289
  • predicted transmembrane helices (TMHMM): 7

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MWIRSRETMKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLTYNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTFFRSWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFVLLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILALKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVISIIQLRVSKKFEI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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