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serotype 4
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D39V
serotype 2
Hungary19A-6
serotype 19A
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670-6B
serotype 6B
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serotype 6A
70585
serotype 5
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A66
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serotype 11A
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serotype 23F
BVJ1JL
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CGSP14
serotype 14
G54
serotype 19F
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serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr1856 [new locus tag: SPR_RS09395 ]
  • pan locus tag?: PNEUPAN003611000
  • symbol: spr1856
  • pan gene symbol?: —
  • synonym:
  • product: Hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr1856 [new locus tag: SPR_RS09395 ]
  • symbol: spr1856
  • product: Hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1831058..1831438
  • length: 381
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTTGGAGCAAGCTCGTTTGAAAGTGGAGCAGCAAGCAATCAAGAATATCCAGTTTTTG
    GAGCAAGATTTACCGAAAAATCCCTTGGAGAAAGAGTTTGATTGCCTTGCTGTTAGTCGG
    GTTCTTCATCATATGCCTGATTTGGATGCGGCTCTCTCACTGTTTCATCAACATTTGAAG
    GAAGATGGGAAACTCATCATTGCTGATTTTACCAAGACAGAAGCTAATCATCATGGATTT
    GATTTAGCTGAACTGGAAAACAAGCTAATTGAGCATGGTTTTTCATCTGTGCATAGTCAG
    ATTCTCTATAGTGCTGAAGACCTGTTTCAAGGAAATCACTCAGAATTCTTTTTAATAGTA
    GCCCAAAAATCACTCGCCTAG
    60
    120
    180
    240
    300
    360
    381

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr1856 [new locus tag: SPR_RS09395 ]
  • symbol: spr1856
  • description: Hypothetical protein
  • length: 126
  • theoretical pI: 5.45253
  • theoretical MW: 14403.3
  • GRAVY: -0.249206

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone ubiquinone/menaquinone biosynthesis methyltransferase (TIGR01934; EC 2.1.1.-; HMM-score: 27.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin malonyl-acyl carrier protein O-methyltransferase BioC (TIGR02072; EC 2.1.1.-; HMM-score: 27.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 3-demethylubiquinone-9 3-O-methyltransferase (TIGR01983; EC 2.1.1.64; HMM-score: 24.5)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs putative 4-mercaptohistidine N1-methyltranferase (TIGR04345; HMM-score: 12.8)
    Metabolism Transport and binding proteins Cations and iron carrying compounds (2,3-dihydroxybenzoyl)adenylate synthase (TIGR02275; EC 2.7.7.58; HMM-score: 12.6)
  • TheSEED  :
    • SAM-dependent methyltransferase
  • PFAM:
    NADP_Rossmann (CL0063) Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 35.8)
    Methyltransf_11; Methyltransferase domain (PF08241; HMM-score: 34.2)
    Methyltransf_12; Methyltransferase domain (PF08242; HMM-score: 31.9)
    Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 31.4)
    Methyltransf_23; Methyltransferase domain (PF13489; HMM-score: 29.8)
    and 6 more
    Ubie_methyltran; ubiE/COQ5 methyltransferase family (PF01209; HMM-score: 27.9)
    NodS; Nodulation protein S (NodS) (PF05401; HMM-score: 16.8)
    CheR; CheR methyltransferase, SAM binding domain (PF01739; HMM-score: 15.9)
    Bmt2; 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 (PF11968; HMM-score: 13.9)
    PDDEXK (CL0236) RE_TaqI; TaqI restriction endonuclease (PF09573; HMM-score: 13.5)
    NADP_Rossmann (CL0063) NNMT_PNMT_TEMT; NNMT/PNMT/TEMT family (PF01234; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000726
    • TAT(Tat/SPI): 0.000075
    • LIPO(Sec/SPII): 0.000103
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEFDCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIEHGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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