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serotype 4
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D39V
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EF3030
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serotype 6B
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serotype 6A
70585
serotype 5
A026
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A66
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AP200
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ASP0581
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ATCC 49619
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BM6001
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CGSP14
serotype 14
G54
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HU-OH
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr1911 [new locus tag: SPR_RS09740 ]
  • pan locus tag?: PNEUPAN003768000
  • symbol: ctpC
  • pan gene symbol?: ctpC
  • synonym:
  • product: P-type ATPase - metal/cation transport

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr1911 [new locus tag: SPR_RS09740 ]
  • symbol: ctpC
  • product: P-type ATPase - metal/cation transport
  • replicon: chromosome
  • strand: -
  • coordinates: 1889977..1892049
  • length: 2073
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    GTGAATAATATGTCTTTTAAAGTGCTACATAGAGGATACCAACATATCCGACTATCATCT
    TCTTTTTCACTTACCTTGGATATTCAAGACTATCTTCGTTCCTTGGCGAGAGATGAAAAG
    GGGATTGAGTCTATCCAGTTTTACATGGATCAACAGCACTTTACTCTACGCATAAAAGAA
    GGCTTTTCTGTATTAGATAATGCAGAAGCCTTTTTAAAAAGAATTGATAAAGGGAAAGTT
    TCTGAGTTGATGACTCTTCCCATTCGTAGAGAAGAGAGTGCTTATTCTATTGTTTCAGGT
    GCAGCGGTTAAGCGTGTACTTTTTCGTAGTTTTGTGCCGTATCCTATTCGCTATATATGG
    ACTTGTTATCAGGCTTTGGGTTATATTAGAGAAGCCTATCAAACACTAGCGCGTAAGGAA
    CTAACGATGGAAGTCTTGGACTGTTCGGCTATTTTATTGTCCTTGTTTATGAACCAATCC
    AAGACAGCTAGCAATATCATGTTTATGCTTGATTTGGGGAATCATTTAGATCAGTGGTCC
    TTGAAAAAAACTGCAACAGATTTAGAACAGAGTCTTCTTGCAAAAGAGAGCGATGTATTC
    CTAGTACAGGGCGATACGGTTGTTAGTATCAAGAGTTCCGATGTTCAAATAGGAGATGTC
    TTGATCTTATCTCAAGGAAATGAAATTCTGTTTGATGGACAAGTAGTTTCAGGTTTAGGT
    ATGGTCAACGAAAGTTCCTTGACAGGAGAGAGTTTTCCAGTTGAAAAAAGAGAGTCTGAT
    TTGGTTTGTGCAAATACAGTATTAGAAACTGGAGAGTTACGCATTCGTGTAACAGATAAT
    CAGATGAACAGCCGTATTTTACAGCTGATTGAGTTGATGAAGAAATCTGAAGAAAACAAG
    AAAACGAAACAACGCTATTTCATCAAGATGGCGGATAAAGTCGTCAAATATAATTTCTTG
    GGGTCTGGGCTGACTTACCTATTGACAGGTTCTTTTTCTAAGGCTATTTCTTTCCTATTG
    GTCGATTTCTCCTGCGCTTTGAAAATCTCTACTCCTGTAGCTTATTTGACAGTTATCAAG
    GAAGGGTTGAACCGTGAAATGGTGATTAAGGATGGAGATGTTCTGGAGAAATATCTGGAA
    GTTGATACTTTCTTGTTTGATAAGACAGGAACAATCACAACTAGTTATCCTATAGTTGAA
    AAGGTGTTACCTTTTGGAGACTATAGTGAGGAAGATATTCTCAGAATCAGTGCCTGTCTT
    GAGGAACACATTTATCATCCTATTGCTAATGCCATCGTCAAGCAAGCTGAGATAGAGGGA
    ATTGAACATGAGGAAATGCATGGGAAACTCCAATATATCGCAAGCAAGGGGATCAAATCT
    CATATAGATGGCCAACCAGTTCTTATTGGGAATTATGTCTTGATGCAGGATGAGCAGATT
    CATATCAGTTCAGAACAAAATGCTTTAATTGAAGAGTACAAGAGTCACTACAATCTCTTA
    TTCTTGGCTTATCAAAATGAATTGATTGGAATGTTCTGCATTCATACTCCTTTGAGAAAA
    GAAGCAAAAACAGCCTTGGATAAACTTAAGGCACAGGGGAAAAAATTGATTCTGGCAACA
    GGAGACACCTTGATTAGGACAGAGGAATTAGTCAAAGATTTGCCCTTTGATCAGGTCTAT
    ACAGACTTGAAACCTGATGGGAAATTTGAGTTAGTAGAGAAACTGCAGAAAGCAGGTCAC
    ACTATTTTGATGGTTGGAGATGGATTGAATGACTCAGCGGCTCTAACTCTATCAGATATC
    GGTGTGGTGATGAATGAGAGTGCAGATATTTCTAAGCAGATGAGTGATATCTTATTGTTA
    GATAATCGTTTGGATTTCTTCCAAGAGTTGGATTCGTTATCATCATCTTTGCAAACACTC
    ATCAAGAAAAATATTCAAGATACCGTTGTCGTAAATAGTAGTTTGATTGGCTTCGGCTTA
    TTTAATTGGCTCAGTCCTTCAAATCTCTCTATCTTACATAATCTAACAACCTTGCGCATT
    GTCCTGCGTAGCCTGTCTATTAAAAATAGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2073

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr1911 [new locus tag: SPR_RS09740 ]
  • symbol: CtpC
  • description: P-type ATPase - metal/cation transport
  • length: 690
  • theoretical pI: 5.56788
  • theoretical MW: 77948.4
  • GRAVY: -0.0568116

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.3.10?  ExPASy
    Hydrogen/potassium-exchanging ATPase ATP + H2O + H+(In) + K+(Out) = ADP + phosphate + H+(Out) + K+(In)
  • TIGRFAM:
    heavy metal translocating P-type ATPase (TIGR01525; EC 3.6.3.-; HMM-score: 523.1)
    and 18 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds cadmium-translocating P-type ATPase (TIGR01512; EC 3.6.3.3; HMM-score: 285)
    Cellular processes Cellular processes Detoxification copper-translocating P-type ATPase (TIGR01511; EC 3.6.3.4; HMM-score: 265.5)
    Metabolism Transport and binding proteins Cations and iron carrying compounds copper-translocating P-type ATPase (TIGR01511; EC 3.6.3.4; HMM-score: 265.5)
    HAD ATPase, P-type, family IC (TIGR01494; EC 3.6.3.-; HMM-score: 259)
    plasma-membrane proton-efflux P-type ATPase (TIGR01647; EC 3.6.3.6; HMM-score: 112.2)
    Metabolism Transport and binding proteins Cations and iron carrying compounds K+-transporting ATPase, B subunit (TIGR01497; EC 3.6.3.12; HMM-score: 106.6)
    calcium-translocating P-type ATPase, PMCA-type (TIGR01517; EC 3.6.3.8; HMM-score: 85.5)
    P-type ATPase of unknown pump specificity (type V) (TIGR01657; HMM-score: 79.9)
    Metabolism Transport and binding proteins Cations and iron carrying compounds magnesium-translocating P-type ATPase (TIGR01524; EC 3.6.3.2; HMM-score: 71.3)
    calcium-transporting P-type ATPase, PMR1-type (TIGR01522; EC 3.6.3.8; HMM-score: 60.6)
    Metabolism Energy metabolism ATP-proton motive force interconversion Na,H/K antiporter P-type ATPase, alpha subunit (TIGR01106; EC 3.6.3.-; HMM-score: 54.8)
    Metabolism Transport and binding proteins Cations and iron carrying compounds calcium-translocating P-type ATPase, SERCA-type (TIGR01116; EC 3.6.3.8; HMM-score: 54.4)
    potassium/sodium efflux P-type ATPase, fungal-type (TIGR01523; EC 3.6.3.-; HMM-score: 47.2)
    Unknown function Enzymes of unknown specificity Cof-like hydrolase (TIGR00099; HMM-score: 31.8)
    sucrose-phosphate phosphatase subfamily (TIGR01482; EC 3.1.3.-; HMM-score: 23.2)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIB (TIGR01484; HMM-score: 16.9)
    Metabolism Central intermediary metabolism Other 2,3-diketo-5-methylthio-1-phosphopentane phosphatase (TIGR01489; HMM-score: 16.5)
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 12.1)
  • TheSEED  :
    • Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.-)
  • PFAM:
    HAD (CL0137) Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 107.4)
    no clan defined E1-E2_ATPase; E1-E2 ATPase (PF00122; HMM-score: 104.6)
    and 3 more
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 33.7)
    NADP_Rossmann (CL0063) CoA_binding_3; CoA-binding domain (PF13727; HMM-score: 13.3)
    HAD (CL0137) HAD_2; haloacid dehalogenase-like hydrolase (PF13419; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.04
    • Cytoplasmic Membrane Score: 9.96
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9986
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0013
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008296
    • TAT(Tat/SPI): 0.00049
    • LIPO(Sec/SPII): 0.00057
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNNMSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTASNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGSGLTYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSLSIKNR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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