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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A66
  • locus tag: A66_RS03470 [old locus tag: A66_00698 ]
  • pan locus tag?: PNEUPAN001705000
  • symbol: sodA
  • pan gene symbol?: sodA
  • synonym:
  • product: superoxide dismutase SodA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: A66_RS03470 [old locus tag: A66_00698 ]
  • symbol: sodA
  • product: superoxide dismutase SodA
  • replicon: chromosome
  • strand: +
  • coordinates: 671520..672125
  • length: 606
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LN847353 (671520..672125) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0667 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGCTATTATCTTACCAGAACTTCCATATGCATACGACGCTTTGGAACCATACATCGAT
    GCGGAAACAATGCATTTGCACCATGACAAACACCATCAAACTTATGTCAACAATGCCAAT
    GCAGCTTTAGAAAAACACCCTGAAATCGGTGAAGACCTTGAAGCCTTGCTTGCTGATGTA
    GAATCTATCCCAGCTGATATCCGTCAAGCACTTATCAACAATGGTGGCGGACACTTGAAC
    CACGCTCTTTTCTGGGAATTGATGACTCCCGAGAAAACAGCTCCTTCAGCAGAACTGACA
    GCAGCAATCGATGCAACATTTGGTTCATTTGAAGAATTCCAAGCAGCCTTCACTGCAGCA
    GCAACAACTCGTTTTGGTTCAGGTTGGGCATGGTTGGTTGTCAACAAAGAAGGGAAACTT
    GAAGTGACTTCAACAGCAAACCAAGATACACCAATCTCAGAAGGTAAAAAACCAATCTTG
    GGCTTGGACGTTTGGGAACATGCTTACTACGTGAAATACCGCAACGTGCGTCCTGACTAC
    ATCAAAGCTTTCTTTTCAGTAATCAACTGGAATAAAGTAGATGAATTGTACGCAGCTGCT
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    606

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: A66_RS03470 [old locus tag: A66_00698 ]
  • symbol: SodA
  • description: superoxide dismutase SodA
  • length: 201
  • theoretical pI: 4.7051
  • theoretical MW: 22427
  • GRAVY: -0.244776

⊟Function[edit | edit source]

  • reaction:
    EC 1.15.1.1?  ExPASy
    Superoxide dismutase 2 superoxide + 2 H+ = O2 + H2O2
  • TIGRFAM:
    OHCU decarboxylase (TIGR03180; EC 4.1.1.-; HMM-score: 12.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Sod_Fe_C; Iron/manganese superoxide dismutases, C-terminal domain (PF02777; HMM-score: 138.5)
    and 2 more
    Sod_Fe_N; Iron/manganese superoxide dismutases, alpha-hairpin domain (PF00081; HMM-score: 109.1)
    SLATT (CL0676) SLATT_1; SMODS and SLOG-associating 2TM effector domain 1 (PF18181; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9566
    • Cytoplasmic Membrane Score: 0.0004
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0427
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004745
    • TAT(Tat/SPI): 0.000204
    • LIPO(Sec/SPII): 0.000556
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000974749 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALEKHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELTAAIDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPILGLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

H Yesilkaya, A Kadioglu, N Gingles, J E Alexander, T J Mitchell, P W Andrew
Role of manganese-containing superoxide dismutase in oxidative stress and virulence of Streptococcus pneumoniae.
Infect Immun: 2000, 68(5);2819-26
[PubMed:10768978] [WorldCat.org] [DOI] (P p)

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