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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 24-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Hungary19A-6
- locus tag: SPH_RS04175 [old locus tag: SPH_0865 ]
- pan locus tag?: PNEUPAN001705000
- symbol: sodA
- pan gene symbol?: sodA
- synonym:
- product: superoxide dismutase SodA
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPH_RS04175 [old locus tag: SPH_0865 ]
- symbol: sodA
- product: superoxide dismutase SodA
- replicon: chromosome
- strand: +
- coordinates: 804148..804753
- length: 606
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_010380 (804148..804753) NCBI
- BioCyc: SPH_RS04175 BioCyc
- MicrobesOnline: see SPH_0865
- PneumoBrowse for strain D39V: SPV_0667 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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541
601ATGGCTATTATCTTACCAGAACTTCCATATGCATACGACGCTTTGGAACCATACATCGAT
GCGGAAACAATGCATTTGCACCATGACAAACACCATCAAACTTATGTCAACAATGCCAAT
GCAGCTTTAGAAAAACACCCTGAAATCGGTGAAGACCTTGAAGCCTTGCTTGCTGATGTA
GAATCTATCCCAGCTGATATCCGTCAAGCACTTATCAACAATGGTGGCGGACACTTGAAC
CACGCTCTTTTCTGGGAATTGATGACTCCCGAGAAAACAGCTCCTTCAGCAGAACTGGCA
GCAGCAATCGATGCAACATTTGGTTCATTTGAAGAATTTCAAGCAGCCTTCACTGCAGCA
GCAACAACTCGTTTTGGTTCAGGTTGGGCATGGTTGGTTGTCAACAAAGAAGGGAAACTT
GAAGTGACTTCAACAGCAAACCAAGACACACCAATCTCAGAAGGTAAAAAACCAATCTTG
GGCTTGGACGTTTGGGAACATGCTTACTACGTGAAATACCGCAACGTGCGTCCTGACTAC
ATCAAAGCTTTCTTTTCAGTAATCAACTGGAATAAAGTAGATGAATTGTACGCAGCTGCT
AAATAA60
120
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540
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606
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPH_RS04175 [old locus tag: SPH_0865 ]
- symbol: SodA
- description: superoxide dismutase SodA
- length: 201
- theoretical pI: 4.7051
- theoretical MW: 22397
- GRAVY: -0.232338
⊟Function[edit | edit source]
- reaction: EC 1.15.1.1? ExPASySuperoxide dismutase 2 superoxide + 2 H+ = O2 + H2O2
- TIGRFAM: OHCU decarboxylase (TIGR03180; EC 4.1.1.-; HMM-score: 12.5)
- TheSEED: see SPH_0865
- PFAM: no clan defined Sod_Fe_C; Iron/manganese superoxide dismutases, C-terminal domain (PF02777; HMM-score: 139.3)and 2 moreSod_Fe_N; Iron/manganese superoxide dismutases, alpha-hairpin domain (PF00081; HMM-score: 109.1)SLATT (CL0676) SLATT_1; SMODS and SLOG-associating 2TM effector domain 1 (PF18181; HMM-score: 12.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0.01
- Cytoplasmic Membrane Score: 0.09
- Cellwall Score: 0.18
- Extracellular Score: 9.72
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9501
- Cytoplasmic Membrane Score: 0.0004
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.0492
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004745
- TAT(Tat/SPI): 0.000204
- LIPO(Sec/SPII): 0.000556
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALEKHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAAIDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPILGLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0667 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
H Yesilkaya, A Kadioglu, N Gingles, J E Alexander, T J Mitchell, P W Andrew
Role of manganese-containing superoxide dismutase in oxidative stress and virulence of Streptococcus pneumoniae.
Infect Immun: 2000, 68(5);2819-26
[PubMed:10768978] [WorldCat.org] [DOI] (P p)