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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 09-DEC-2016
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SP49
- locus tag: BMJ42_00002 [new locus tag: BMJ42_RS00010 ]
- pan locus tag?: PNEUPAN000169000
- symbol: dnaN
- pan gene symbol?: dnaN
- synonym:
- product: DNA polymerase III, beta subunit
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: BMJ42_00002 [new locus tag: BMJ42_RS00010 ]
- symbol: dnaN
- product: DNA polymerase III, beta subunit
- replicon: chromosome
- strand: +
- coordinates: 1521..2657
- length: 1137
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: CP018136 (1521..2657) NCBI
- BioCyc: see BMJ42_RS00010
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0002 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1081ATGATTCATTTTTCAATTAATAAAAATTTATTTCTACAAGCATTAAATACTACTAAGAGA
GCTATTAGTTCTAAAAATGCCATTCCTATTTTATCAACAGTAAAAATTGACGTGACCAAT
GAAGGTATTACTTTAATTGGTTCAAATGGTCAAATTTCAATTGAAAATTTTATTTCTCAA
AAAAATGAAGATGCTGGTTTGTTAATTACTTCTTTAGGTTCGATCCTTCTTGAAGCTTCT
TTCTTTATCAATGTAGTATCTAGTTTACCTGATGTAACTCTTGATTTTAAAGAAATTGAA
CAAAATCAAATTGTTTTAACCAGTGGCAAATCAGAAATTACCCTAAAAGGAAAAGATAGC
GAACAATATCCACGAATCCAAGAAATTTCAGCAAGCACTCCTTTAATACTTGAAACAAAA
TTACTCAAGAAAATTATTAATGAAACAGCCTTTGCTGCAAGTACACAAGAGAGTCGTCCG
ATTTTAACAGGTGTCCACTTCGTATTGAGTCAACACAAAGAGTTAAAAACAGTTGCAACA
GACTCTCATCGCCTAAGCCAGAAAAAATTGACTCTTGAAAAAAATAGTGATGATTTTGAT
GTCGTAATTCCTAGCCGTTCTCTACGCGAATTTTCAGCGGTATTTACAGATGATATCGAA
ACTGTAGAGATTTTCTTTGCCAATAACCAAATCCTCTTTAGAAGCGAAAATATTAGCTTC
TATACTCGTCTCCTAGAAGGAAACTATCCTGATACAGATCGCTTGATTCCAACAGACTTT
AACACTACTATTACTTTTAATGTGGTAAACTTACGCCAGTCAATGGAGCGTGCCCGTCTT
TTATCAAGTGCGACTCAAAATGGTACTGTGAAACTTGAAATTAAGGATGGGGTTGTTAGC
GCCCATGTTCACTCTCCAGAAGTTGGTAAAGTAAACGAAGAAATCGATACTGATCAGGTT
ACTGGTGAAGATTTGACCATTAGTTTCAACCCAACTTACTTGATTGATTCTCTTAAAGCT
TTAAATAGCGAAAAGGTGACCATTAGCTTTATCTCAGCTGTTCGTCCATTTACTCTTGTG
CCAGCAGATACTGACGAAGACTTCATGCAGCTCATTACACCAGTTCGTACAAATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: BMJ42_00002 [new locus tag: BMJ42_RS00010 ]
- symbol: DnaN
- description: DNA polymerase III, beta subunit
- length: 378
- theoretical pI: 4.79238
- theoretical MW: 42072.4
- GRAVY: -0.111111
⊟Function[edit | edit source]
- reaction: EC 2.7.7.7? ExPASyDNA-directed DNA polymerase Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
- TIGRFAM: DNA metabolism DNA replication, recombination, and repair DNA polymerase III, beta subunit (TIGR00663; EC 2.7.7.7; HMM-score: 309.6)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: DNA_clamp (CL0060) DNA_pol3_beta_2; DNA polymerase III beta subunit, central domain (PF02767; HMM-score: 118.9)DNA_pol3_beta; DNA polymerase III beta subunit, N-terminal domain (PF00712; HMM-score: 110.5)DNA_pol3_beta_3; DNA polymerase III beta subunit, C-terminal domain (PF02768; HMM-score: 104.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.8854
- Cytoplasmic Membrane Score: 0.0838
- Cell wall & surface Score: 0.0074
- Extracellular Score: 0.0234
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.00964
- TAT(Tat/SPI): 0.000845
- LIPO(Sec/SPII): 0.001491
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: APJ29351 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0002 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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