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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 09-DEC-2016
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SP49
- locus tag: BMJ42_00401 [new locus tag: BMJ42_RS02120 ]
- pan locus tag?: PNEUPAN001032000
- symbol: manL
- pan gene symbol?: manL
- synonym: manX
- product: PTS system mannose-specific transporter subunit IIAB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: BMJ42_00401 [new locus tag: BMJ42_RS02120 ]
- symbol: manL
- product: PTS system mannose-specific transporter subunit IIAB
- replicon: chromosome
- strand: -
- coordinates: 345978..346967
- length: 990
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP018136 (345978..346967) NCBI
- BioCyc: see BMJ42_RS02120
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0264 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGAGTATCGGAATCATTATTGCGAGCCACGGCGAATTTGCTGCGGGTATTCATCAGTCA
GGATCTATGATCTTTGGTGAACAAGAAAAGGTTCAAGTTGTGACCTTTATGCCAAATGAA
GGTCCTGATGATCTATACGCTAAGTTTAATAACGCTGTTGCTGCATTTGACGCAGAAGAT
GAGGTTCTAGTTTTGGCTGACCTTTGGAGTGGTTCTCCATTTAACCAAGCTAGTCGCGTG
ATGGGAGAAAATCCTGAGCGTAAGTTTGCCATCATCACAGGACTTAACTTACCGATGTTG
ATTCAAGCCTACACAGAGCGCCTCATGGACGCTGCTGCAGGTGTAGAAAAAGTCGCTGCT
AATATCATTAAAGAAGCCAAAGATGGCATCAAAGCTCTTCCAGAAGAGCTAAATCCAGTT
GAAGAAGTTGCAAGCGCTGCAGCTGCTCCAGTTGCCCAAACTGCTATCCCAGAAGGAACT
GTTATCGGAGACGGTAAATTGAAAATCAATCTTGCCCGTCTTGACACACGTCTACTTCAC
GGTCAGGTTGCAACTGCTTGGACTCCAGATTCAAAAGCAAATCGTATCATCGTTGCTTCA
GATAACGTGGCTAAAGACGACCTTCGTAAAGAATTGATTAAACAAGCAGCTCCAGGTAAT
GTCAAGGCTAACGTGGTTCCAATTCAAAAACTGATTGAGATTTCAAAAGACCCACGTTTT
GGAGAAACACATGCCCTTATCTTGTTTGAAACACCTCAAGATGCCCTTCGTGCCATCGAA
GGCGGCGTGCCAATCAAGACTCTTAATGTTGGTTCTATGGCTCACTCAACAGGTAAAACA
TTGGTCAATACCGTTTTGTCTATGGACAAAGAAGACGTTGCTACATTTGAAAAAATGCGT
GACTTGGGTGTTGAATTTGATGTCCGTAAAGTACCAAATGATTCTAAAAAAGATTTGTTT
GACTTGATTAACAAAGCCAATGTCAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: BMJ42_00401 [new locus tag: BMJ42_RS02120 ]
- symbol: ManL
- description: PTS system mannose-specific transporter subunit IIAB
- length: 329
- theoretical pI: 4.91903
- theoretical MW: 35443.4
- GRAVY: -0.0793313
⊟Function[edit | edit source]
- reaction: EC 2.7.1.191? ExPASyProtein-N(pi)-phosphohistidine--D-mannose phosphotransferase [Protein]-N(pi)-phospho-L-histidine + D-mannose(Side 1) = [protein]-L-histidine + D-mannose 6-phosphate(Side 2)
- TIGRFAM: Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IIB component (TIGR00854; EC 2.7.1.69; HMM-score: 152.6)Signal transduction PTS PTS system, mannose/fructose/sorbose family, IIB component (TIGR00854; EC 2.7.1.69; HMM-score: 152.6)and 2 moreTransport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IIA component (TIGR00824; EC 2.7.1.69; HMM-score: 97.3)Signal transduction PTS PTS system, mannose/fructose/sorbose family, IIA component (TIGR00824; EC 2.7.1.69; HMM-score: 97.3)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: no clan defined PTSIIB_sorb; PTS system sorbose subfamily IIB component (PF03830; HMM-score: 167)and 2 moreEDD (CL0245) EIIA-man; PTS system fructose IIA component (PF03610; HMM-score: 122.6)no clan defined Pro_Al_protease; Alpha-lytic protease prodomain (PF02983; HMM-score: 11.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.67
- Cytoplasmic Membrane Score: 0.01
- Cellwall Score: 0.15
- Extracellular Score: 0.17
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.014909
- TAT(Tat/SPI): 0.00058
- LIPO(Sec/SPII): 0.003977
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: APJ29737 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDDLYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQAYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGTVIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAPGNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHSTGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0264 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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