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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 09-DEC-2016
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SP49
- locus tag: BMJ42_00616 [new locus tag: BMJ42_RS03295 ]
- pan locus tag?: PNEUPAN001431000
- symbol: nusA
- pan gene symbol?: nusA
- synonym:
- product: transcription elongation factor NusA
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: BMJ42_00616 [new locus tag: BMJ42_RS03295 ]
- symbol: nusA
- product: transcription elongation factor NusA
- replicon: chromosome
- strand: +
- coordinates: 559468..560592
- length: 1125
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: CP018136 (559468..560592) NCBI
- BioCyc: see BMJ42_RS03295
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0479 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1021
1081ATGCTAGAGGCCTTCCGCATTTTGGAAGAAGACAAGGGAATCAAAAAAGAAGACATCATC
GACGCAGTAGTAGAGTCGCTTCGTTCCGCTTATCGCAGACGCTATGGTCAGTCAGACAGC
GTAGCTATTGACTTCAACGAAAAAACAGGTGACTTTACAGTTTATACTGTCCGTGAAGTT
GTTGATGAAGTATTTGATAGCCGTTTGGAAATCAGCTTGAAAGATGCTCTTGCCATTAAT
TCAGCTTATGAACTTGGAGACAAAATCAAGTTTGAAGAAGCACCAGCTGAGTTTGGTCGT
GTAGCAGCCCAATCTGCCAAACAAACCATCATGGAAAAAATGCGCAAGCAAACACGTGCC
ATCACTTACAATACTTACAAAGAACATGAGCAAGAAATCATGTCTGGTACAGTAGAACGC
TTTGACAACCGCTTTATCTATGTCAACCTTGGTAGCATCGAAGCCCAATTGTCAAAACAA
GACCAAATTCCTGGAGAAGTTTTTGCTTCTCATGATCGTATCGAAGTTTATGTTTACAAG
GTTGAAGACAACCCTCGTGGTGTGAACGTCTTTGTTAGCCGTAGCCATCCAGAAATGATC
AAACGTTTGATGGAGCAAGAAATTCCAGAAGTTTATGATGGAACTGTTGAAATCATGAGC
GTGGCTCGTGAAGCAGGTGACCGTACGAAGGTTGCTGTTCGTAGCCACAATCCAAACGTG
GATGCTATCGGTACAATCGTTGGACGTGGTGGTGCTAATATCAAGAAGATTACTAGCAAA
TTCCACCCAGCTCGTTACGATGCTAAAAATGATCGCATGGTACCAATCGAAGAAAATATC
GATGTTATCGAGTGGGTAGCAGATCCAGCTGAATTTATCTACAATGCCATCGCTCCTGCT
GAGGTTGACCAAGTTATCTTTGATGAAAACGACAGCAAACGTGCCTTGGTGGTTGTTCCA
GATAACAAGCTTTCTCTTGCCATTGGTCGTCGTGGACAAAACGTGCGCTTGGCGGCTCAC
TTGACTGGTTACCGTATCGATATCAAGTCTGCTAGCGAATTTGAAGCCATGGAAGACGCT
GCTTCAGTAGAGTTGGAAGTAGAAAACGATACTGTAGAAGAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: BMJ42_00616 [new locus tag: BMJ42_RS03295 ]
- symbol: NusA
- description: transcription elongation factor NusA
- length: 374
- theoretical pI: 4.59129
- theoretical MW: 42321.3
- GRAVY: -0.43984
⊟Function[edit | edit source]
- TIGRFAM: Transcription Transcription factors transcription termination factor NusA (TIGR01953; HMM-score: 373)and 2 moreNusA family KH domain protein, archaeal (TIGR01952; HMM-score: 46.2)Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein uS3 (TIGR01008; HMM-score: 13.8)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: no clan defined NusA_N; NusA N-terminal domain (PF08529; HMM-score: 108.4)and 5 moreKH (CL0007) KH_5; NusA-like KH domain (PF13184; HMM-score: 69.1)KH_2; KH domain (PF07650; HMM-score: 37.8)KH_1; KH domain (PF00013; HMM-score: 29.7)OB (CL0021) S1; S1 RNA binding domain (PF00575; HMM-score: 18.9)no clan defined DUF6243; Family of unknown function (DUF6243) (PF19756; HMM-score: 14.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9444
- Cytoplasmic Membrane Score: 0.0026
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.0527
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003044
- TAT(Tat/SPI): 0.000556
- LIPO(Sec/SPII): 0.000666
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: APJ29944 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDSVAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEFGRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQLSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDGTVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDRMVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGRRGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0479 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]