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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-MAY-2019

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_00065 [new locus tag: EF3030_RS00065 ]
  • pan locus tag?: PNEUPAN000297000
  • symbol: EF3030_00065
  • pan gene symbol?: comX1
  • synonym:
  • product: sigma-70 family RNA polymerase sigma factor

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS, pseudogene
  • locus tag: EF3030_00065 [new locus tag: EF3030_RS00065 ]
  • symbol: EF3030_00065
  • product: sigma-70 family RNA polymerase sigma factor
  • replicon: chromosome
  • strand: +
  • coordinates: 14450..14928
  • length: 479
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATAT
    TACCTTCATTTATGGGAATTATCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAA
    TTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCACGTTTAAGGAAATATTTCAAA
    ACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
    TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGGGTC
    TCTGGCTAGATGATTATTATCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAA
    GTAAAGAGAAACAAGAAGAACTAGAACGTGTCTTAAGCAATGAACGATTTCGAGGGCGTC
    AAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG
    60
    120
    180
    240
    300
    360
    420
    479

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: EF3030_00065 [new locus tag: EF3030_RS00065 ]
  • symbol: EF3030_00065
  • description: sigma-70 family RNA polymerase sigma factor
  • length:
  • theoretical pI:
  • theoretical MW:
  • GRAVY:

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for D39, TIGR4
  • PFAM:

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by ComX1, sigma factor, controls the expression of late competence genes: in D39, TIGR4

Localization[edit | edit source]

  • PSORTb:
  • SignalP:
  • predicted transmembrane helices (TMHMM):

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

M S Lee, D A Morrison
Identification of a new regulator in Streptococcus pneumoniae linking quorum sensing to competence for genetic transformation.
J Bacteriol: 1999, 181(16);5004-16
[PubMed:10438773] [WorldCat.org] [DOI] (P p)