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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS10980 [old locus tag: SPAT_2076 ]
  • pan locus tag?: PNEUPAN003895000
  • symbol: pspC
  • pan gene symbol?: pspC
  • synonym:
  • product: pneumococcal surface protein PspC, LPXTG-anchored form

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS10980 [old locus tag: SPAT_2076 ]
  • symbol: pspC
  • product: pneumococcal surface protein PspC, LPXTG-anchored form
  • replicon: chromosome
  • strand: -
  • coordinates: 2043646..2045442
  • length: 1797
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (2043646..2045442) NCBI
  • BioCyc: EL263_RS10980 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGTTTAAATCAAATCATGAGCGAAGAATGCGTTATTCCATTCGTAAATTTAGTGTAGGA
    GTAGCTAGCGTAGCTGTTGCCAGTCTTTTTATGGGAAGTGTTGTACATGCGACAGAGAAA
    GAGGGAAGTACCCAAGCAGCCACTTCTTTTAATAGGGGAAATGGAAGTCAGGCAGAACAA
    CGTGGAGAACTCGATTTAGAACGAGATAAGGCAATGAAAGCGGTCAGTGAATATGTAGGA
    AAAATGGTGAGAGATGCCTATGTAAAATCAGATAGAAAACGACATAAAAATACTGTAGCT
    CTAGTTAACCAGTTGGGAAACATTAAGAACAGGTATTTGAATGAAATAGTTCATTCAACC
    TCAAAAAGCCAACTACAGGAACTGATGATGAAGAGTCAATCAGAAGTAGATGAAGCTGTG
    TCTAAATTTGAAAAGGACTCATTTTCTTCGTCAAGTTCAGGATCCTCCACTAAACCAGAA
    ACTCCGCAGCCGGAAAATCCAGAGCATCAAAAACCAACAACTCCATCTCCGGATACCAAA
    CCAAGCCCTCAACCAGAAGGCAAGAAACCAAGCGTACCAGACATTAATCAGGAAAAAGAA
    AAAGCTAAGCTTGCTGTAGTAACCTACATGAGCAAGATTTTAGATGATATACAAAAACAT
    CATCTGCAGAAAGAAAAACATCGTCAGATTGTTGCTCTTATTAAGGAGCTTGATGAGCTT
    AAAAAGCAAGCTCTTTCTGAAATTGATAATGTAAATACCAAAGTAGAAATTGAAAATACA
    GTCCACAAGATATTTGCAGACATGGATGCAGTTGTGACTAAATTCAAAAAAGGCTTAACT
    CAGGACACACCAAAAGAACCAGGTAACAAAAAACCATCTGCTCCAAAACCAGGTATGCAA
    CCAAGTCCTCAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCG
    CAGCTAGAAAAACCAAAACCAGAGGTTAAACCGCAGCCGGAAAAACCAAAACCAGAGGTT
    AAACCGCAGCCGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCA
    GAGGTTAAACCGCAGCTAGAAAAACCAAAACCAGAGGTTAAACCGCAGCCGGAAAAACCA
    AAACCAGAGGTTAAACCGCAGCCGGAAAAACCAAAACCAGAGGTTAAACCGCAGCCGGAA
    AAACCAAAACCAGAGGTTAAACCGCAGCCGGAAAAACCAAAACCAGAGGTTAAACCGCAG
    CCGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAA
    CCGCAGCTAGAAAAACCAAAACCAGAGGTTAAACCGCAGCCGGAAAAACCAAAACCAGAG
    GTTAAACCGCAGCCGGAAAAACCAAAACCAGAGGTTAAACCGCAGCCGGAAAAACCAAAA
    CCAGAGGTTAAACCGCAGCCGGAAAAACCAAAACCAGAGGTTAAACCGCAGCCGGAAAAA
    CCAAAACCAGAGGTTAAACCGCAACCAGAAAAACCAAAACCAGAGGTTAAACCGCAGCCG
    GAAAAACCAAAACCAGATAATAGCAAGCCACAAGCAGATGATAAGAAGCCATCAACTACA
    AATAATTTAAGCAAGGACAAGCAACCTTCTAACCAAGCTTCAACAAACGAAAAAGCAACA
    AATAAACCGAAGAAGTCATTGCCATCAACTGGATCTATTTCAAATCTAGCACTTGAAATT
    GCAGGTCTTCTTACCTTGGCGGGGGCAACCATTCTTGCTAAGAAAAGAATGAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1797

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS10980 [old locus tag: SPAT_2076 ]
  • symbol: PspC
  • description: pneumococcal surface protein PspC, LPXTG-anchored form
  • length: 598
  • theoretical pI: 10.4229
  • theoretical MW: 66987.7
  • GRAVY: -1.33913

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 60.3)
    and 2 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 22.3)
    GeoRSP system SPASM domain protein (TIGR04304; HMM-score: 11.9)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    no clan defined RICH; RICH domain (PF05062; HMM-score: 171.3)
    and 5 more
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 46.6)
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 34.8)
    EDD (CL0245) Dak1; Dak1 domain (PF02733; HMM-score: 15.8)
    EFTPs (CL0575) Ribosomal_L35Ae; Ribosomal protein L35Ae (PF01247; HMM-score: 13.9)
    B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 7.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0049
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0.9093
    • Extracellular Score: 0.0855
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.962543
    • TAT(Tat/SPI): 0.028766
    • LIPO(Sec/SPII): 0.003054
    • Cleavage Site: CS pos: 37-38. VHA-TE. Pr: 0.9041
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_114880796 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGSTQAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALVNQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPETPQPENPEHQKPTTPSPDTKPSPQPEGKKPSVPDINQEKEKAKLAVVTYMSKILDDIQKHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGATILAKKRMK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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