PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 07-MAR-2025

⊟Summary

• organism: Streptococcus pneumoniae Hu17
• locus tag: SPNHU17_RS10515 [old locus tag: SPNHU17_02254 ]
• pan locus tag^?: PNEUPAN003895000
• symbol: SPNHU17_RS10515
• pan gene symbol^?: pspC
• synonym:
• product: RICH domain-containing protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNHU17_RS10515 [old locus tag: SPNHU17_02254 ]
• symbol: SPNHU17_RS10515
• product: RICH domain-containing protein
• replicon: chromosome
• strand: -
• coordinates: <2098131..2098966
• length: 836
• essential: unknown

⊟Accession numbers

• Location: NZ_CP020549 <2098131..2098966 NCBI
• BioCyc: SPNHU17_RS10515 BioCyc
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
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  301
  361
  421
  481
  541
  601
  661
  721
  781
  
  ATGTTTGATGAGGCTTCGAGTAAAGAAAACGTGGAAAACTTGATAAAAGAAGCTAAACAG
  GAGATAGAAGCTCTAGTCGTTAAACATAAGGGGCGAGAAATTGACTTAGAACGAACGAAA
  GCAAAAACCGTAATTGCTAAATATTTAACAGGATTATTAGATGACATCAAGAAAAATTTA
  AAAAAAGAGCAACATATCAATACTGTAGAGCTAATTAAAAAGCTGGGAGACATTAAGCGA
  ACGTATTTGTATAAATTAGATGAATCAACCCAAAAAGCCCAACTACAGGAACTGGTCACA
  GAAAGTCAATCAAAACTAGATGAAGCTTTTTCTAAATTTAAAAATGGCTTATCTTCTTCG
  TCAAGTTCAGGATCCTCCACTAAACCAGAAACTCCGCAGCCGGAAAAACCAGAGCATCAA
  AAACCAACAACTCCAGCTCCGGATACCAAACCAAGCCCTCAACCAGAAGGCAAGAAACCA
  AGCGTACCAGACATTAATCAGGAAAAAGAAAAAGCTAAGCTTGCTGTAGCAACCTACATG
  AGCAAGATTTTAGATGATATACAAAAACATCATCTGCAGAAAGAAAAACATCGTCAGATT
  GTTGCTCTTATTAAGGAGCTTGATGAGCTTAAAAAGCAAGCTCTTTCTGAAATTGATAAT
  GTAAATACCAAAGTAGAAATTGAAAATACAGTCCACAAGATATTTGCAGACATGGATGCA
  GTTGTGACTAAATTCAAAAAAGGCTTAACTCAGGACACACCAAAAGAACCAGGTAACAAA
  AAACCATCTGCTCCAAAACCAGGTATGCAACCAAGTCCTCAACCAGAGGTTAAACC
  60
  120
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  360
  420
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  780
  836
  

⊟Protein

⊟General

• locus tag: SPNHU17_RS10515 [old locus tag: SPNHU17_02254 ]
• symbol: SPNHU17_RS10515
• description: RICH domain-containing protein
• length: 279
• theoretical pI: 9.75624
• theoretical MW: 31339.6
• GRAVY: -0.955197

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Pathogenesis type VI secretion-associated protein, VC_A0119 family (TIGR03362; HMM-score: 14.8)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type VI secretion-associated protein, VC_A0119 family (TIGR03362; HMM-score: 14.8)
  and 1 more
  Genetic information processing DNA metabolism Restriction/modification type II restriction endonuclease, Alw26I/Eco31I/Esp3I family (TIGR02986; EC 3.1.21.4; HMM-score: 9.8)
• TheSEED: data available for Hungary19A-6
• PFAM:
  no clan defined RICH; RICH domain (PF05062; HMM-score: 179)
  and 9 more
  B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 16.6)
  no clan defined HSCB_C; HSCB C-terminal oligomerisation domain (PF07743; HMM-score: 15.6)
  CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like (PF07888; HMM-score: 15.4)
  UBC (CL0208) FANCL_d2; FANCL UBC-like domain 2 (PF18890; HMM-score: 13.5)
  no clan defined Orbi_NS3; Orbivirus NS3 (PF01616; HMM-score: 12.3)
  CdiI_2; CdiI immunity protein (PF18593; HMM-score: 10.1)
  Di-copper (CL0205) Hemocyanin_M; Hemocyanin, copper containing domain (PF00372; HMM-score: 9.2)
  no clan defined Trypan_PARP; Procyclic acidic repetitive protein (PARP) (PF05887; HMM-score: 7.7)
  SieB; Super-infection exclusion protein B (PF14163; HMM-score: 6.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cell wall & surface
  • Cytoplasmic Score: 0.0239
  • Cytoplasmic Membrane Score: 0.0009
  • Cell wall & surface Score: 0.8854
  • Extracellular Score: 0.0898
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002172
  • TAT(Tat/SPI): 0.001442
  • LIPO(Sec/SPII): 0.000644
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_208912246 NCBI
• UniProt:

⊟Protein sequence

• MFDEASSKENVENLIKEAKQEIEALVVKHKGREIDLERTKAKTVIAKYLTGLLDDIKKNLKKEQHINTVELIKKLGDIKRTYLYKLDESTQKAQLQELVTESQSKLDEAFSKFKNGLSSSSSSGSSTKPETPQPEKPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKP

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications