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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 28-AUG-2013

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_10363 [new locus tag: HMPREF0837_RS01835 ]
  • pan locus tag?: PNEUPAN000705000
  • symbol: HMPREF0837_10363
  • pan gene symbol?: cabP
  • synonym:
  • product: TrkA N-terminal domain protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_10363 [new locus tag: HMPREF0837_RS01835 ]
  • symbol: HMPREF0837_10363
  • product: TrkA N-terminal domain protein
  • replicon: chromosome
  • strand: +
  • coordinates: 340450..341136
  • length: 687
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    TTGGTTAAGAAAGGAAAGAGCATGTCAGATCGTACGATTGGAATTTTGGGCTTGGGAATT
    TTTGGGAGCAGTGTCCTAGCTGCCCTAGCCAAGCAGGATATGAATATTATCGCTATTGAT
    GACCACGCAGAGCGCATCAATCAGTTTGAGCCAGTTTTGGCGCGTGGAGTGATTGGTGAC
    ATCACAGATGAAGAATTATTGAGATCAGCAGGGATTGATACCTGCGATACCGTTGTAGTC
    GCGACAGGTGAAAATCTGGAGTCGAGTGTGCTTGCGGTTATGCACTGTAAGAGTTTGGGG
    GTACCGACTGTTATTGCTAAGGTCAAAAGTCAGACCGCTAAGAAAGTGCTAGAAAAGATT
    GGAGCTGACTCGGTTATCTCGCCAGAGTATGAAATGGGGCAGTCTCTAGCACAGACCATT
    CTTTTCCATAATAGTGTTGATGTCTTTCAGTTGGATAAAAATGTGTCTATCGTGGAGATG
    AAAATTCCTCAGTCTTGGGCAGGTCAAAGTCTGAGTAAATTAGACCTCCGTGGCAAATAC
    AATCTGAATATTTTGGGTTTCCGAGAGCAGGAAAATTCCCCATTGGATGTTGAATTTGGA
    CCAGATGACCTCTTGAAAGCAGATACCTATATTTTGGCAGTCATCAACAACCAGTATTTG
    GATACCCTAGTAGCATTGAATTCGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    687

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_10363 [new locus tag: HMPREF0837_RS01835 ]
  • symbol: HMPREF0837_10363
  • description: TrkA N-terminal domain protein
  • length: 228
  • theoretical pI: 4.60036
  • theoretical MW: 24719.2
  • GRAVY: 0.0807018

⊟Function[edit | edit source]

  • TIGRFAM:
    putative phosphonate catabolism associated alcohol dehydrogenase (TIGR03366; HMM-score: 18.9)
    and 4 more
    Metabolism Amino acid biosynthesis Serine family phosphoglycerate dehydrogenase (TIGR01327; EC 1.1.1.95; HMM-score: 13.5)
    Unknown function Enzymes of unknown specificity putative quinone oxidoreductase, YhdH/YhfP family (TIGR02823; HMM-score: 13.2)
    putative enoyl-[acyl-carrier-protein] reductase II (TIGR03151; EC 1.3.1.-; HMM-score: 13)
    nucleotide sugar dehydrogenase (TIGR03026; HMM-score: 12.9)
  • TheSEED  :
    • KtrAB potassium uptake system, peripheral membrane component KtrA
    Potassium metabolism Potassium metabolism - no subcategory Glutathione-regulated potassium-efflux system and associated functions  Trk system potassium uptake protein TrkA
    and 2 more
    Potassium metabolism Potassium metabolism - no subcategory Hyperosmotic potassium uptake  Trk system potassium uptake protein TrkA
    Potassium metabolism Potassium metabolism - no subcategory Potassium homeostasis  Trk system potassium uptake protein TrkA
  • PFAM:
    NADP_Rossmann (CL0063) TrkA_N; TrkA-N domain (PF02254; HMM-score: 95.4)
    and 10 more
    2-Hacid_dh_C; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (PF02826; HMM-score: 24.4)
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase (PF03446; HMM-score: 19.1)
    F420_oxidored; NADP oxidoreductase coenzyme F420-dependent (PF03807; HMM-score: 18.5)
    ADH_zinc_N; Zinc-binding dehydrogenase (PF00107; HMM-score: 17.5)
    Epimerase; NAD dependent epimerase/dehydratase family (PF01370; HMM-score: 15.6)
    ApbA; Ketopantoate reductase PanE/ApbA (PF02558; HMM-score: 14.5)
    Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain (PF03435; HMM-score: 13.9)
    UDPG_MGDP_dh_N; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain (PF03721; HMM-score: 13.7)
    3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain (PF02737; HMM-score: 13.3)
    DAO; FAD dependent oxidoreductase (PF01266; HMM-score: 10.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8709
    • Cytoplasmic Membrane Score: 0.1104
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0187
  • SignalP: Signal peptide SP(Sec/SPI) length 30 aa
    • SP(Sec/SPI): 0.659784
    • TAT(Tat/SPI): 0.036084
    • LIPO(Sec/SPII): 0.045718
    • Cleavage Site: CS pos: 30-31. ALA-KQ. Pr: 0.5461
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADI68591 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVKKGKSMSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEPVLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVKSQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWAGQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVALNS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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