From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_RS12150 [old locus tag: HMPREF0837_12216 ]
  • pan locus tag?: PNEUPAN002559000
  • symbol: HMPREF0837_RS12150
  • pan gene symbol?: —
  • synonym:
  • product: cysteine-rich KTR domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_RS12150 [old locus tag: HMPREF0837_12216 ]
  • symbol: HMPREF0837_RS12150
  • product: cysteine-rich KTR domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2027493..2027684
  • length: 192
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014251 (2027493..2027684) NCBI
  • BioCyc: HMPREF0837_RS12150 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    TTGACTAGCAAACTTACCGCCTCAACATGTCCTGTATGTGGAAATAAAACACGATTAAAG
    ATAAGGGAAGATACTGAATTAAAAAAATTCCCCCTCTATTGTCCGAAATGCAGACAAGAA
    AATTTAATTGAAATAAAGCAGTTCAAAGTAACTGTGATTACAGAGCCAGACGCAAAGACG
    CAGAGCCGATAA
    60
    120
    180
    192

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_RS12150 [old locus tag: HMPREF0837_12216 ]
  • symbol: HMPREF0837_RS12150
  • description: cysteine-rich KTR domain-containing protein
  • length: 63
  • theoretical pI: 9.83187
  • theoretical MW: 7259.52
  • GRAVY: -0.642857

⊟Function[edit | edit source]

  • TIGRFAM:
    cxxc_20_cxxc protein (TIGR04104; HMM-score: 15.2)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions restriction alleviation protein, Lar family (TIGR03655; HMM-score: 13.8)
    Genetic information processing DNA metabolism Restriction/modification restriction alleviation protein, Lar family (TIGR03655; HMM-score: 13.8)
    Genetic information processing Protein fate Protein modification and repair hydrogenase nickel insertion protein HypA (TIGR00100; HMM-score: 13)
    Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 12.6)
    YgiT-type zinc finger domain (TIGR03831; HMM-score: 12.5)
  • TheSEED:
  • PFAM:
    no clan defined Cys_rich_KTR; Cysteine-rich KTR (PF14205; HMM-score: 101.9)
    and 33 more
    Zn_Beta_Ribbon (CL0167) Elf1; Transcription elongation factor Elf1 like (PF05129; HMM-score: 19.7)
    Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 18.9)
    zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 18.9)
    zf-TFIIB; Transcription factor zinc-finger (PF13453; HMM-score: 18.1)
    Nudix_N_2; Nudix N-terminal (PF14803; HMM-score: 17.7)
    no clan defined zf-IS66; zinc-finger binding domain of transposase IS66 (PF13005; HMM-score: 17.4)
    Zn_Beta_Ribbon (CL0167) NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like (PF08772; HMM-score: 16.9)
    no clan defined DUF5679; Domain of unknown function (DUF5679) (PF18930; HMM-score: 16.6)
    Zn_Beta_Ribbon (CL0167) zinc_ribbon_2; zinc-ribbon domain (PF13240; HMM-score: 16.4)
    Zn_ribbon_SprT; SprT-like zinc ribbon domain (PF17283; HMM-score: 15.4)
    Prim_Zn_Ribbon; Zinc-binding domain of primase-helicase (PF08273; HMM-score: 15.3)
    DZR; Double zinc ribbon (PF12773; HMM-score: 15.3)
    no clan defined DNA_ligase_ZBD; NAD-dependent DNA ligase C4 zinc finger domain (PF03119; HMM-score: 15.2)
    Zn_Beta_Ribbon (CL0167) OrfB_Zn_ribbon; Putative transposase DNA-binding domain (PF07282; HMM-score: 15.2)
    no clan defined Cys_rich_CPXG; Cysteine-rich CPXCG (PF14255; HMM-score: 15.2)
    Zn_Beta_Ribbon (CL0167) CpXC; CpXC protein (PF14353; HMM-score: 15.1)
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger (PF01396; HMM-score: 14.9)
    no clan defined HypA; Hydrogenase/urease nickel incorporation, metallochaperone, hypA (PF01155; HMM-score: 14.7)
    Zn_Beta_Ribbon (CL0167) Lar_restr_allev; Restriction alleviation protein Lar (PF14354; HMM-score: 14.7)
    zf-NADH-PPase; NADH pyrophosphatase zinc ribbon domain (PF09297; HMM-score: 14.2)
    OB (CL0021) MCM_OB; MCM OB domain (PF17207; HMM-score: 13.5)
    Zn_Beta_Ribbon (CL0167) zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 13)
    TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 12.9)
    TFIIS_C; Transcription factor S-II (TFIIS) (PF01096; HMM-score: 12.8)
    Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 12.8)
    no clan defined zf-LITAF-like; LITAF-like zinc ribbon domain (PF10601; HMM-score: 12.8)
    C2H2-zf (CL0361) zf-H2C2_2; Zinc-finger double domain (PF13465; HMM-score: 12.8)
    P-loop_NTPase (CL0023) GpA_ATPase; Phage terminase large subunit gpA, ATPase domain (PF05876; HMM-score: 12.5)
    no clan defined DUF3797; Domain of unknown function (DUF3797) (PF12677; HMM-score: 11.9)
    Zn_Beta_Ribbon (CL0167) Auto_anti-p27; Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) (PF06677; HMM-score: 11.8)
    zinc_ribbon_9; zinc-ribbon (PF14369; HMM-score: 11.5)
    C2H2-zf (CL0361) zf-Di19; Drought induced 19 protein (Di19), zinc-binding (PF05605; HMM-score: 10.9)
    RING (CL0229) Prok-RING_4; Prokaryotic RING finger family 4 (PF14447; HMM-score: 10)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9605
    • Cytoplasmic Membrane Score: 0.0239
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0146
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016242
    • TAT(Tat/SPI): 0.001074
    • LIPO(Sec/SPII): 0.012453
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001860868 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTSKLTASTCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTVITEPDAKTQSR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=HMPREF0837_RS12150&oldid=169116"