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serotype 4
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serotype 19A
Hu17
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INV104
serotype 1
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serotype 14
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NCTC7465
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ST556
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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-FEB-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV104
  • locus tag: INV104_06390 [new locus tag: INV104_RS03730 ]
  • pan locus tag?: PNEUPAN001707000
  • symbol: INV104_06390
  • pan gene symbol?: rlmN
  • synonym:
  • product: SAM-dependent methyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: INV104_06390 [new locus tag: INV104_RS03730 ]
  • symbol: INV104_06390
  • product: SAM-dependent methyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 715842..716573
  • length: 732
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGCAGGAATGGGTATTGGAGCAGGGAGAAAAGAAATTCCGTGCAGATCAAATCTGGGAA
    TGGCTCTACCGTAAACGTGTGCAGTCATTTGAAGAAATGACCAACCTTTCCAAGGATTTG
    ATTGCTAAGCTCAATGACCAGTTTGTGGTCAATCCCTTGAAACAAGGTATTGTGCAAGAG
    TCTGCTGATGGTACAGTCAAATATCTCTTTGAATTGCCTGACGGTATGTTAATTGAGACT
    GTACTCATGTGTCAACACTATGGTTTATCTGTCTGTGTGACCACTCAGGTCGGCTGTAAT
    ATCGGTTGTACCTTCTGTGCCTCTGGTTTGATTAAGAAGCAGCGTGACCTCAATAACGGT
    GAAATCGTAGCGCAAATCATGCTGGTTCAGAAATACTTTGATGAGCGTGGTCAGGATGAA
    CGCATCAGCCATATCGTTGTCATGGGAATCGGTGAGCCCTTTGATAATTACAACAATGTC
    TTGAATTTCTTTCGTACTATCAATGATGATAAAGGAATGGCTATCGGTGCTCGTCACATC
    ACGGTTTCAATCTCAGGTTTGGCTCATAAAATTCGTGACTTTGCTGATGAAGGGGTTCAG
    GTCAATCTTGCCGTGTCTCTTCACGCACCCAACAATGAACTTCGTTCAAGTATCATGAAG
    ATTAACCGTGCCTTTCCGATTAGACTTGTTCGGAATCTAGTTCACTTCATAATTGATGAT
    GGCACAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    732

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: INV104_06390 [new locus tag: INV104_RS03730 ]
  • symbol: INV104_06390
  • description: SAM-dependent methyltransferase
  • length: 243
  • theoretical pI: 6.24485
  • theoretical MW: 27650.6
  • GRAVY: -0.146502

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification 23S rRNA (adenine(2503)-C(2))-methyltransferase (TIGR00048; EC 2.1.1.192; HMM-score: 288.2)
    and 11 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr (TIGR04432; EC 2.1.1.224; HMM-score: 145.6)
    tungsten cofactor oxidoreducase radical SAM maturase (TIGR04317; HMM-score: 20.9)
    radical SAM enzyme, TIGR04100 family (TIGR04100; HMM-score: 16.8)
    Genetic information processing Protein fate Protein modification and repair quinohemoprotein amine dehydrogenase maturation protein (TIGR03906; HMM-score: 15.7)
    Genetic information processing Protein fate Protein modification and repair pyruvate formate-lyase 1-activating enzyme (TIGR02493; EC 1.97.1.4; HMM-score: 14.8)
    Metabolism Energy metabolism Anaerobic pyruvate formate-lyase 1-activating enzyme (TIGR02493; EC 1.97.1.4; HMM-score: 14.8)
    Genetic information processing Protein synthesis tRNA and rRNA base modification MiaB-like tRNA modifying enzyme (TIGR01579; HMM-score: 13.8)
    Genetic information processing Protein fate Protein modification and repair anaerobic ribonucleoside-triphosphate reductase activating protein (TIGR02495; EC 1.97.-.-; HMM-score: 13.8)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides 2'-Deoxyribonucleotide metabolism anaerobic ribonucleoside-triphosphate reductase activating protein (TIGR02495; EC 1.97.-.-; HMM-score: 13.8)
    radical SAM/SPASM domain protein maturase (TIGR04463; HMM-score: 13.4)
    AmmeMemoRadiSam system radical SAM enzyme (TIGR04337; HMM-score: 11.5)
  • TheSEED  :
    • Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-)
  • PFAM:
    TIM_barrel (CL0036) Radical_SAM; Radical SAM superfamily (PF04055; HMM-score: 45.7)
    and 5 more
    4Fe-4S (CL0344) Fer4_14; 4Fe-4S single cluster domain (PF13394; HMM-score: 32.4)
    Fer4_12; 4Fe-4S single cluster domain (PF13353; HMM-score: 21.1)
    no clan defined zf-C2HC5; Putative zinc finger motif, C2HC5-type (PF06221; HMM-score: 13.4)
    P63C; P63C domain (PF10546; HMM-score: 13.3)
    TIM_barrel (CL0036) Radical_SAM_2; Radical SAM-like domain (PF19238; HMM-score: 8.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7639
    • Cytoplasmic Membrane Score: 0.1875
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0481
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002023
    • TAT(Tat/SPI): 0.000105
    • LIPO(Sec/SPII): 0.000274
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW36322 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQEWVLEQGEKKFRADQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVMGIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVSLHAPNNELRSSIMKINRAFPIRLVRNLVHFIIDDGTN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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