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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 05-OCT-2017
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae MDRSPN001
- locus tag: MDRSPN_02054 [new locus tag: MDRSPN_RS10810 ]
- pan locus tag?: PNEUPAN003950000
- symbol: spo0J
- pan gene symbol?: parB
- synonym:
- product: chromosome segregation protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: MDRSPN_02054 [new locus tag: MDRSPN_RS10810 ]
- symbol: spo0J
- product: chromosome segregation protein
- replicon: chromosome
- strand: +
- coordinates: 2044107..2044850
- length: 744
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AP018391 (2044107..2044850) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_2069 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGATTTCTATCACAGATATACAAAAAAATCCCTATCAACCCCGAAAAGAATTTGATAGA
GAAAAACTAGATGAACTAGCACAGTCTATCAAAGAAAATGGGGTCATTCAACCGATTATT
GTTCGTCAATCTCCTGTTATTGGTTATGAAATCCTTGCAGGAGAGAGACGCTATCGGGCT
TCACTTTTAGCTGGTCTACGGTCTATCCCAGCTGTTGTTAAACAGATTTCAGACCAAGAG
ATGATGGTCCAGTCCATTATTGAAAATTTACAGAGAGAAAATTTAAACCCAATAGAAGAA
GCATGCGCCTATGAATCTCTCGTAGAGAAAGGATTCACCCATGCTGAAATTGCAGATAAA
ATGGGCAAGTCTCGTCCATATATCAGCAACTCCATTCGTTTACTTTCCTTGCCAGAACAG
ATTCTCTCAGAAGTAGAAAATGGCAAACTATCACAAGCCCATGCGCGTTCCCTAGTTGGG
TTAAATAAGGAACAACAAGACTATTTCTTTCAACGGATTATAGAAGAAGATATTTCTGTA
AGGAAGTTAGAAACTCTTCTGACAGAGAAAAAACAAAAGAAACAGCAAAAAACTAATCAT
TTCATACAAAATGAAGAAAAACAGTTAAGAAAACTACTCGGATTAGATGTAGAAATTAAA
CTATCTAAAAAAGACAGTGGAAAAATCATTATTTCTTTTTCAAATCAAGAAGAATATAGT
AGAATTATCAACAGCCTGAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: MDRSPN_02054 [new locus tag: MDRSPN_RS10810 ]
- symbol: Spo0J
- description: chromosome segregation protein
- length: 247
- theoretical pI: 8.8707
- theoretical MW: 28465.5
- GRAVY: -0.5583
⊟Function[edit | edit source]
- TIGRFAM: nucleoid occlusion protein (TIGR04285; HMM-score: 221.2)ParB/RepB/Spo0J family partition protein (TIGR00180; HMM-score: 192.8)and 2 morePRTRC system ParB family protein (TIGR03734; HMM-score: 130.6)Mobile and extrachromosomal element functions Plasmid functions plasmid partitioning protein RepB (TIGR03454; HMM-score: 74.4)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: ParBc (CL0248) ParBc; ParB/Sulfiredoxin domain (PF02195; HMM-score: 98.7)and 8 moreHTH (CL0123) HTH_ParB; HTH domain found in ParB protein (PF17762; HMM-score: 48.1)RepB; RepB plasmid partitioning protein (PF07506; HMM-score: 24.5)KorB; KorB domain (PF08535; HMM-score: 19.6)HTH_3; Helix-turn-helix (PF01381; HMM-score: 17.9)no clan defined Mu-like_Pro; Mu-like prophage I protein (PF10123; HMM-score: 16.6)HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 14.8)Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 13.9)Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 12.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.98
- Cytoplasmic Membrane Score: 0.0117
- Cell wall & surface Score: 0.0022
- Extracellular Score: 0.0062
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005077
- TAT(Tat/SPI): 0.000646
- LIPO(Sec/SPII): 0.000566
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: BBA60195 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPIIVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNPIEEACAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHARSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLLGLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_2069 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Anita Minnen, Laetitia Attaiech, Maria Thon, Stephan Gruber, Jan-Willem Veening
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae.
Mol Microbiol: 2011, 81(3);676-88
[PubMed:21651626] [WorldCat.org] [DOI] (I p)