PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN003307000
• symbol^?: mga2
• synonym: mgaSpn
• description^?: virulence factor transcriptional regulator MgaSpn

  descriptions from strain specific annotations:

  • virulence factor transcriptional regulator MgaSpn
  • putative Mga-like regulatory protein
  • M protein trans-acting positive transcriptional regulator
  • aspartate aminotransferase
  • Capsule synthesis positive regulator AcpB
  • transcriptional activator
  • M protein trans-acting positive regulator (MGA)
  • putative transcriptional activator
  • transcriptional activator, putative
  • Conserved hypothetical protein
  • Mga-like repressor A MgrA
  • M protein trans-acting positive regulator Mga2
  • M trans-acting positive regulator (MGA) HTH domain protein
  • Putative trans-acting regulator
  • pseudogene
• strand^?: -
• coordinates^?: 4335341..4336822
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS08935 (mgaSpn)
(2)
D39:
SPD_RS08460 (mgaSpn)
(2)
D39V:
SPV_RS08455 (mgaSpn)
(19A)
Hungary19A-6:
SPH_RS09335 (mgaSpn)
(19F)
EF3030:
EF3030_RS08600 (mgaSpn)
(6B)^?
670-6B:
SP670_RS09335 (mgaSpn)
(6A)
6A-10:
HKM25_RS09005 (mgaSpn)
(5)
70585:
SP70585_RS09195 (mgaSpn)
(19F)
A026:
T308_RS08340 (mgaSpn)
(3)
A66:
A66_RS07995 (mgaSpn)
(11A)
AP200:
SPAP_RS08865 (mgaSpn)
(12F)
ASP0581:
EL334_RS09130 (mgaSpn)
(19F)
ATCC 49619:
EL263_RS08670 (mgaSpn)
(23F)
ATCC 700669:
SPN23F_RS09140 (mgaSpn)
(19F)
BM6001:
ODS73_RS09305 (mgaSpn)
(1)
BVJ1JL:
JN057_RS08645 (mgaSpn)
(14)
CGSP14:
SPCG_RS09205 (mgaSpn)
(19F)
G54:
SPG_RS08415 (mgaSpn)
(1)
gamPNI0373:
HMPREF1038_RS08645 (mgaSpn)
(3)
HU-OH:
EL271_RS08735 (mgaSpn)
(19A)
Hu15:
SPNHU15_RS08590 (mgaSpn)
(19A)
Hu17:
SPNHU17_RS08575 (mgaSpn)
(1)
INV104:
INV104_RS08850 (mgaSpn)
(14)
INV200:
SPNINV200_RS08610 (mgaSpn)
(14)
JJA:
SPJ_RS08440 (mgaSpn)
(19F)
MDRSPN001:
MDRSPN_RS08140 (mgaSpn)
(1)
NCTC7465:
AT689_RS05120 (mgaSpn)
(2)
NCTC7466:
DQM66_RS08455 (mgaSpn)
(4)
NU83127:
EL277_RS09080 (mgaSpn)
(3)
OXC141:
SPNOXC_RS08530 (mgaSpn)
(1)
P1031:
SPP_RS08870 (mgaSpn)
(2)
R6:
SPR_RS08055 (mgaSpn)
(19A)
SP49:
BMJ42_RS09535 (mgaSpn)
(1)
SPN032672:
SPN032672_RS03735 (mgaSpn)
(3)
SPN034156:
SPN034156_RS03550 (mgaSpn)
(3)
SPN034183:
SPN034183_RS08555 (mgaSpn)
(3)
SPN994038:
SPN994038_RS08455 (mgaSpn)
(3)
SPN994039:
SPN994039_RS08460 (mgaSpn)
(3)
SPNA45:
SPNA45_RS02680 (mgaSpn)
(19F)
ST556:
MYY_RS08780 (mgaSpn)
(19F)
Taiwan19F-14:
SPT_RS08575 (mgaSpn)
(19A)
TCH8431/19A:
HMPREF0837_RS09715 (mgaSpn)
(4)
Xen35:
CXP32_RS09030 (mgaSpn)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS
  D39             MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS
  D39V            MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS
  Hungary19A-6    MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS
  EF3030          MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS
                  ************************************************************
  
  TIGR4           STNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRI
  D39             STNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRI
  D39V            STNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRI
  Hungary19A-6    STNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRI
  EF3030          STNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRI
                  ************************************************************
  
  TIGR4           ISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQL
  D39             ISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQL
  D39V            ISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQL
  Hungary19A-6    ISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQL
  EF3030          ISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQL
                  ************************************************************
  
  TIGR4           LELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEG
  D39             LELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEG
  D39V            LELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEG
  Hungary19A-6    LELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEG
  EF3030          LELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEG
                  ************************************************************
  
  TIGR4           VAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQ
  D39             VAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQ
  D39V            VAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQ
  Hungary19A-6    VAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQ
  EF3030          VAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQ
                  ************************************************************
  
  TIGR4           ISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDIKK
  D39             ISVKYQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKK
  D39V            ISVKYQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKK
  Hungary19A-6    ISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDIKK
  EF3030          ISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDIKK
                  ********:************************************************:**
  
  TIGR4           ELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVA
  D39             ELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVA
  D39V            ELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVA
  Hungary19A-6    EISHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVA
  EF3030          ELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVA
                  *:**********************************************************
  
  TIGR4           ETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLI
  D39             ETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLI
  D39V            ETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLI
  Hungary19A-6    ETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLI
  EF3030          ETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLI
                  ************************************************************
  
  TIGR4           YLLNAMMFIRLDE
  D39             YLLNAMMFIRLDE
  D39V            YLLNAMMFIRLDE
  Hungary19A-6    YLLNAMMFIRLDE
  EF3030          YLLNAMMFIRLDE
                  *************