PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN003528000
• symbol^?: lytA
• synonym:
• description^?: N-acetylmuramoyl-L-alanine amidase LytA

  descriptions from strain specific annotations:

  • N-acetylmuramoyl-L-alanine amidase LytA
  • autolysin
  • putative cell wall-binding amidase
  • autolysin (N-acetylmuramoyl-L-alanine amidase) (Mureinhydrolase) (Mucopeptide aminohydrolase) (Cell wall hydrolase)
  • N-acetylmuramoyl-L-alanine amidase
  • Autolysin (N-acetylmuramoyl-L-alanine amidase)
  • autolysin/N-acetylmuramoyl-L-alanine amidase
  • Autolysin/N-acetylmuramoyl-L-alanine amidase LytA
  • Cell wall-associated murein hydrolase LytA
  • gametolysin
  • Glucan-binding domain (YG repeat)
  • N-acetylmuramoyl-L-alanine amidase family protein
  • Thiol-activated cytolysin
  • thiol-activated cytolysin family protein
  • pseudogene
• strand^?: -
• coordinates^?: 4625180..4658569
• occurrence^?: in 93% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS09740 (lytA)
(2)
D39:
SPD_RS09250 (lytA)
(2)
D39V:
SPV_RS09245 (lytA)
(19A)
Hungary19A-6:
SPH_RS10205 (lytA)
(19F)
EF3030:
EF3030_RS09435 (lytA)
(6B)^?
670-6B:
SP670_RS10190 (lytA)
(6A)
6A-10:
HKM25_RS09755 (lytA)
(5)
70585:
SP70585_RS10020 (lytA)
(19F)
A026:
T308_RS09175 (lytA)
(3)
A66:
A66_RS08745 (lytA)
(11A)
AP200:
SPAP_RS09690 (lytA)
(12F)
ASP0581:
EL334_RS09945 (lytA)
(19F)
ATCC 49619:
EL263_RS09510 (lytA)
(23F)
ATCC 700669:
SPN23F_RS09995 (lytA)
(19F)
BM6001:
ODS73_RS10105 (lytA)
(1)
BVJ1JL:
JN057_RS09455 (lytA)
(14)
CGSP14:
SPCG_RS10020 (lytA)
(19F)
G54:
SPG_RS09245 (lytA)
(1)
gamPNI0373:
HMPREF1038_RS09455 (lytA)
(3)
HU-OH:
EL271_RS09560 (lytA)
(19A)
Hu15:
SPNHU15_RS09260 (lytA)
(19A)
Hu17:
SPNHU17_RS09250 (lytA)
(1)
INV104:
INV104_RS09685 (lytA)
(14)
INV200:
SPNINV200_RS09430 (lytA)
(14)
JJA:
SPJ_RS09580 (lytA)
(19F)
MDRSPN001:
MDRSPN_RS08975 (lytA)
(1)
NCTC7465:
—
(2)
NCTC7466:
DQM66_RS09245 (lytA)
(4)
NU83127:
EL277_RS09920 (lytA)
(3)
OXC141:
SPNOXC_RS09360 (lytA)
(1)
P1031:
SPP_RS09695 (lytA)
(2)
R6:
SPR_RS08815 (lytA)
(19A)
SP49:
BMJ42_RS10425 (lytA)
(1)
SPN032672:
—
(3)
SPN034156:
—
(3)
SPN034183:
SPN034183_RS09380 (lytA)
(3)
SPN994038:
SPN994038_RS09285 (lytA)
(3)
SPN994039:
SPN994039_RS09290 (lytA)
(3)
SPNA45:
SPNA45_RS14355
(19F)
ST556:
MYY_RS09620 (lytA)
(19F)
Taiwan19F-14:
SPT_RS09420 (lytA)
(19A)
TCH8431/19A:
HMPREF0837_RS10555 (lytA)
(4)
Xen35:
CXP32_RS09855 (lytA)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGC
  D39             MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGC
  D39V            MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGC
  Hungary19A-6    MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGC
  EF3030          MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGC
                  ************************************************************
  
  TIGR4           IMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPK
  D39             IMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPK
  D39V            IMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPK
  Hungary19A-6    IMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPK
  EF3030          IMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPK
                  ************************************************************
  
  TIGR4           TLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQK
  D39             TLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQK
  D39V            TLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQK
  Hungary19A-6    TLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQK
  EF3030          TLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQK
                  ************************************************************
  
  TIGR4           NDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATG
  D39             NDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATG
  D39V            NDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATG
  Hungary19A-6    NDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATG
  EF3030          NDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATG
                  ************************************************************
  
  TIGR4           WKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGT
  D39             WKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGT
  D39V            WKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGT
  Hungary19A-6    WKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGT
  EF3030          WKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGT
                  ************************************************************
  
  TIGR4           LADKPEFTVEPDGLITVK
  D39             LADRPEFTVEPDGLITVK
  D39V            LADRPEFTVEPDGLITVK
  Hungary19A-6    LADKPEFTVEPDGLITVK
  EF3030          LADKPEFTVEPDGLITVK
                  ***:**************