PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN003923000
• symbol^?: comE
• synonym:
• description^?: competence system response regulator transcription factor ComE

  descriptions from strain specific annotations:

  • competence system response regulator transcription factor ComE
  • Response regulator
  • putative response regulator protein
  • Accessory gene regulator A
  • DNA-binding response regulator
  • LytR family transcriptional regulator
  • response regulator ComE
  • ComE response regulator TCS12
  • LytTr DNA-binding domain protein
  • Response regulator of the competence regulon ComE
  • Response regulator of the LytR/AlgR family
  • response regulator transcription factor
  • response regulstor transcription fsctor [protein A]
  • Two-component system response regulator ComE
• strand^?: +
• coordinates^?: 5111654..5112406
• occurrence^?: in 98% of 41 strains

⊟Orthologs

TIGR4:
SP_RS11425 (comE)
D39:
SPD_RS10920 (comE)
D39V:
SPV_RS10915 (comE)
Hungary19A-6:
SPH_RS11900 (comE)
EF3030:
EF3030_RS11080 (comE)
670-6B:
SP670_RS12080 (comE)
6A-10:
HKM25_RS11350 (comE)
70585:
SP70585_RS11735 (comE)
A026:
T308_RS10940 (comE)
A66:
A66_RS00005 (comE)
AP200:
SPAP_RS11285 (comE)
ASP0581:
EL334_RS11680 (comE)
ATCC 49619:
EL263_RS11210 (comE)
ATCC 700669:
SPN23F_RS11660 (comE)
BVJ1JL:
JN057_RS11020 (comE)
CGSP14:
SPCG_RS11650 (comE)
G54:
SPG_RS10900 (comE)
gamPNI0373:
—
HU-OH:
EL271_RS11185 (comE)
Hu15:
SPNHU15_RS10755 (comE)
Hu17:
SPNHU17_RS10735 (comE)
INV104:
INV104_RS11330 (comE)
INV200:
SPNINV200_RS11065 (comE)
JJA:
SPJ_RS11210 (comE)
MDRSPN001:
MDRSPN_RS10780 (comE)
NCTC7466:
DQM66_RS10915 (comE)
NU83127:
EL277_RS11630 (comE)
OXC141:
SPNOXC_RS10945 (comE)
P1031:
SPP_RS11290 (comE)
R6:
SPR_RS10400 (comE)
SP49:
BMJ42_RS12165 (comE)
SPN032672:
SPN032672_RS04505 (comE)
SPN034156:
SPN034156_RS05945 (comE)
SPN034183:
SPN034183_RS10960 (comE)
SPN994038:
SPN994038_RS10875 (comE)
SPN994039:
SPN994039_RS10880 (comE)
SPNA45:
SPNA45_RS11580 (comE)
ST556:
MYY_RS11370 (comE)
Taiwan19F-14:
SPT_RS11155 (comE)
TCH8431/19A:
HMPREF0837_RS01275 (comE)
Xen35:
CXP32_RS11580 (comE)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEV
  D39             MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEV
  D39V            MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEV
  Hungary19A-6    MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEV
  EF3030          MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEV
                  ************************************************************
  
  TIGR4           ALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKVLGTEHVLYAILHDSNALA
  D39             ALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKVLGTEHVLYAILHDGNALA
  D39V            ALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKVLGTEHVLYAILHDGNALA
  Hungary19A-6    ALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKVLGTEHVLYAILHDGNALA
  EF3030          ALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKVLGTEHVLYAILHDSNALA
                  *************************:*****************************.****
  
  TIGR4           TRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKALRQRHRTVADKQNSMANMMG
  D39             TRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKALRQRHRTVADKQNSMANMMG
  D39V            TRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKALRQRHRTVADKQNSMANMMG
  Hungary19A-6    TRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKALRQRHRTVADKQNSMANMMG
  EF3030          TRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKALRQRHRTVADKQNSMANMMG
                  ************************************************************
  
  TIGR4           MPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
  D39             MPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
  D39V            MPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
  Hungary19A-6    MPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
  EF3030          MPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
                  ************************************************************
  
  TIGR4           TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQV
  D39             TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQV
  D39V            TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQV
  Hungary19A-6    TALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQV
  EF3030          TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQV
                  ****************.*******************************************
  
  TIGR4           ILFIDELHTIMGSGSGIDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRR
  D39             ILFIDELHTIMGSGSGIDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRR
  D39V            ILFIDELHTIMGSGSGIDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRR
  Hungary19A-6    ILFIDELHTIMGSGSGIDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRR
  EF3030          ILFIDELHTIMGSGSGIDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRR
                  ************************************************************
  
  TIGR4           FAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVETAVKMAHRYLTSRHLPDSAID
  D39             FAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVETAVKMAHRYLTSRHLPDSAID
  D39V            FAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVETAVKMAHRYLTSRHLPDSAID
  Hungary19A-6    FAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVETAVKMAHRYLTSRHLPDSAID
  EF3030          FAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVETAVKMAHRYLTSRHLPDSAID
                  ************************************************************
  
  TIGR4           LLDEAAATVQNKAKHVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
  D39             LLDEAAATVQNKAKHVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
  D39V            LLDEAAATVQNKAKHVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
  Hungary19A-6    LLDEAAATVQNKANHVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
  EF3030          LLDEAAATVQNKAKHVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
                  *************:**********************************************
  
  TIGR4           LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKR
  D39             LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKR
  D39V            LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKR
  Hungary19A-6    LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKR
  EF3030          LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKR
                  ************************************************************
  
  TIGR4           PIGSFMFLGPTGVGKTELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGY
  D39             PIGSFMFLGPTGVGKTELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGY
  D39V            PIGSFMFLGPTGVGKTELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGY
  Hungary19A-6    PIGSFMFLGPTGVGKTELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGY
  EF3030          PIGSFMFLGPTGVGKTELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGY
                  ************************************************************
  
  TIGR4           EEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIM
  D39             EEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIM
  D39V            EEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIM
  Hungary19A-6    EEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIM
  EF3030          EEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIM
                  ************************************************************
  
  TIGR4           TSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
  D39             TSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
  D39V            TSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
  Hungary19A-6    TSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
  EF3030          TSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
                  ************************************************************
  
  TIGR4           DHMQEVVKIMVKPLVASLTEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDK
  D39             DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDK
  D39V            DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDK
  Hungary19A-6    DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDK
  EF3030          DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDK
                  ******************:*****************************************
  
  TIGR4           LAELLLKGDLVAGSTLKIGVKAGQLKFDIA
  D39             LAELLLKGDLVAGSILKIGVKAGQLKFDIA
  D39V            LAELLLKGDLVAGSILKIGVKAGQLKFDIA
  Hungary19A-6    LAELLLKGDLVAGSTLKIGVKAGQLKFDIA
  EF3030          LAELLLKGDLVAGSTLKIGVKAGQLKFDIA
                  ************** ***************