From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_0670 [new locus tag: SP70585_RS03295 ]
  • pan locus tag?: PNEUPAN001536000
  • symbol: SP70585_0670
  • pan gene symbol?: glnP2a
  • synonym:
  • product: ABC transporter membrane-spanning permease - glutamine transport

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_0670 [new locus tag: SP70585_RS03295 ]
  • symbol: SP70585_0670
  • product: ABC transporter membrane-spanning permease - glutamine transport
  • replicon: chromosome
  • strand: -
  • coordinates: 600280..600957
  • length: 678
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACAGATTTATCATCTTGGACAGCCTATTTTCAGGATTTTGAACAATTTTTCAATGGT
    TTCCTCTTTACTCTTGCCCTAGCGATTGGATCCTTTATCCTCGCCATGGTCTTAGGAATC
    TTCTTTGGTGCCATGTCAACCAGTAAACGTCCAATTTTACGCATTTTAGCTCGCATCTTT
    GTTGAATTTTACCAAAATACTCCTCTCTTGGTGCAGTTTGTTATTGTTTTTTATGGCCTA
    CCTCTTATCAGTGACCATATCATCATGATTCCAATTTATTGGACAGCCGTTCTCTGCGTG
    GGACTCTATCACGGCGCTTATATCGCTGAGGTTATTCGTTCAGGGATTCAGTCTATTCCT
    AGTGGTCAGATGGAGGCCGCCTTGTCGCAAGGTTTTACCTATATCAGTGCCATGCGCTTG
    ATTACCTTGCCTCAGGCCTTCCGCATCATTCTCCCTCCATTGACCAACCAAATTGTTAAC
    CTCATCAAGAACACATCTACTGTAGCTATCATCTCTGGAGTAGACTTGATGTTTGTGACT
    AAGTCTTGGTCGGCTCTCAACGGAAACTATATCCCAGCCTTTTTAGGTGCTGCTCTTCTC
    TACTTTGCCCTATGCTTCCCTGTTGCCCAGTTTGGTCGCAAGATGGAGCAAGCCAATAAA
    AAAGCCTATTCACTTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    678

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_0670 [new locus tag: SP70585_RS03295 ]
  • symbol: SP70585_0670
  • description: ABC transporter membrane-spanning permease - glutamine transport
  • length: 225
  • theoretical pI: 9.27134
  • theoretical MW: 25085.6
  • GRAVY: 0.745333

⊟Function[edit | edit source]

  • TIGRFAM:
    ectoine/hydroxyectoine ABC transporter, permease protein EhuC (TIGR03004; HMM-score: 127.8)
    ectoine/hydroxyectoine ABC transporter, permease protein EhuD (TIGR03003; HMM-score: 116.8)
    and 5 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family (TIGR01726; HMM-score: 85.7)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 28.7)
    choline ABC transporter, permease protein (TIGR03416; HMM-score: 18.9)
    Metabolism Transport and binding proteins Other K-Cl cotransporter (TIGR00930; HMM-score: 14.9)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 13.8)
  • TheSEED  :
    • Glutamate transport permease protein
    Stress Response Acid stress Glutamate transporter involved in acid tolerance in Streptococcus  Glutamate transport permease protein
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 65.8)
    and 1 more
    no clan defined DUF3272; Protein of unknown function (DUF3272) (PF11676; HMM-score: 11.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001111
    • TAT(Tat/SPI): 0.002137
    • LIPO(Sec/SPII): 0.003047
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTDLSSWTAYFQDFEQFFNGFLFTLALAIGSFILAMVLGIFFGAMSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGLYHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVNLIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQANKKAYSL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: GlnR* (repression) regulon
    GlnR*(TF)important in Nitrogen assimilation; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP70585_0670&oldid=29905"