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serotype 4
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EF3030
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70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
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serotype 19A
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serotype 19A
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serotype 14
JJA
serotype 14
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serotype 19F
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serotype 2
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serotype 4
OXC141
serotype 3
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serotype 1
R6
serotype 2
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serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_0671 [new locus tag: SP70585_RS03300 ]
  • pan locus tag?: PNEUPAN001537000
  • symbol: SP70585_0671
  • pan gene symbol?: glnH2
  • synonym:
  • product: amino acid ABC transporter, amino acid-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_0671 [new locus tag: SP70585_RS03300 ]
  • symbol: SP70585_0671
  • product: amino acid ABC transporter, amino acid-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 600970..601734
  • length: 765
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    TTGATTAGCCTTTTCGGCCTTGCTGCTGCCAAACCAGTCCAGGCTGATACTAGTATCGCA
    GACATTCAAAAAAGAGGCGAACTGGTTGTCGGTGTCAAACAAGACGTTCCCAATTTTGGT
    TACAAAGATCCCAAGACCGGTACTTATTCTGGTATCGAAACCGACTTGGCCAAGATGGTA
    GCTGATGAACTCAAGGTCAAGATTCGCTATGTGCCGGTTACAGCACAAACCCGCGGCCCC
    CTTCTAGACAATGAACAGGTCGATATGGATATCGCGACCTTTACCATCACGGACGAACGC
    AAAAAACTCTACAACTTTACCAGTCCCTACTACACAGACGCTTCTGGATTTTTGGTCAAT
    AAATCTGCCAAAATCAAAAAGATTGAGGACCTAAACGGCAAAACCATCGGAGTCGCCCAA
    GGCTCCATCACCCAACGCCTGATTACTGAACTGGGCAAAAAGAAAGGTCTAACCTTTAAA
    TTTGTCGAACTTGGTTCCTACCCAGAATTGATTACTTCCCTGCACGCTCATCGTATCGAT
    GCCTTTTCCGTTGACCGCTCTATTCTATCTGGCTACACTAATAAACGGACAGCACTACTA
    GATGATAGTTTCAAGCCATCTGACTACGGTATTGTTACCAAGAAATCAAATACAGAGCTC
    AACGACTATCTTGATAACTTGGTTACTAAATGGAGCAAGGATGGTAGTTTGCAGAAACTT
    TATGACCGTTACAAGCTCAAACCATCTAGTCATACCGCAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    765

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_0671 [new locus tag: SP70585_RS03300 ]
  • symbol: SP70585_0671
  • description: amino acid ABC transporter, amino acid-binding protein
  • length: 254
  • theoretical pI: 9.54563
  • theoretical MW: 28247
  • GRAVY: -0.414173

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 148.7)
    and 9 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 42.5)
    extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 32.7)
    Metabolism Transport and binding proteins Other ABC transporter, substrate-binding protein, aliphatic sulfonates family (TIGR01728; HMM-score: 28.8)
    Metabolism Transport and binding proteins Unknown substrate TRAP transporter solute receptor, TAXI family (TIGR02122; HMM-score: 24.9)
    quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein (TIGR03871; HMM-score: 20.6)
    Metabolism Transport and binding proteins Anions phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein (TIGR01098; HMM-score: 17.7)
    Metabolism Energy metabolism Other methanol oxidation system protein MoxJ (TIGR03870; HMM-score: 17.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids methanol oxidation system protein MoxJ (TIGR03870; HMM-score: 17.4)
    taurine ABC transporter, periplasmic binding protein (TIGR01729; HMM-score: 12.6)
  • TheSEED  :
    • Glutamate transport substrate-binding protein
    Stress Response Acid stress Glutamate transporter involved in acid tolerance in Streptococcus  Glutamate transport substrate-binding protein
  • PFAM:
    PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 170)
    and 5 more
    NMT1; NMT1/THI5 like (PF09084; HMM-score: 37.8)
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 27.5)
    Phosphonate-bd; ABC transporter, phosphonate, periplasmic substrate-binding protein (PF12974; HMM-score: 27)
    YhfZ_C; YhfZ C-terminal domain (PF14503; HMM-score: 23.8)
    NMT1_3; NMT1-like family (PF16868; HMM-score: 17)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.179434
    • TAT(Tat/SPI): 0.004974
    • LIPO(Sec/SPII): 0.012236
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: GlnR* (repression) regulon
    GlnR*(TF)important in Nitrogen assimilation; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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