PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 31-JAN-2014

⊟Summary

• organism: Streptococcus pneumoniae 70585
• locus tag: SP70585_1629 [new locus tag: SP70585_RS08065 ]
• pan locus tag^?: PNEUPAN002990000
• symbol: SP70585_1629
• pan gene symbol^?: oxlT
• synonym:
• product: oxalate:formate antiporter

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SP70585_1629 [new locus tag: SP70585_RS08065 ]
• symbol: SP70585_1629
• product: oxalate:formate antiporter
• replicon: chromosome
• strand: -
• coordinates: 1505953..1506834
• length: 882
• essential: unknown

⊟Accession numbers

• Location: CP000918 (1505953..1506834) NCBI
• BioCyc: see SP70585_RS08065
• MicrobesOnline: 7477551 MicrobesOnline
• PneumoBrowse for strain D39V: SPV_1414 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  ATGAAATCGAATCGTTATATTATTGCCTTTGCTGGGGTCATTTTACACTTAATGCTGGGT
  TCGACTTATGCTTGGAGTGTTTATCGTAACCCTATTATTGAAAAAACGGGATGGGATCAG
  GCTTCTGTTGCCTTCGCCTTTAGTCTAGCAATCTTTTGTTTGGGCTTATCGGCTGCATTT
  ATGGGGCGTTTGGTAGAAAAATTTGGTCCGAAAGTCATGGGGAGTCTATCTGCTTTTCTA
  TACGCAGGTGGAAATATCTTAACAGGATTTGCAATAGACCGTCAGGAACTGTGGTTGTTG
  TATCTAGCTTATGGCATTTTAGGTGGGCTTGGTTTGGGAGCAGGCTATATTACCCCTGTG
  TCAACGATTATAAAATGGTTTCCTGATAAACGTGGTCTCGCAACAGGTTTAGCGATTATG
  GGGTTTGGTTTTGCTTCTTTATTGACTAGTCCCATAGCGCAACACCTCATCGCAGGGGTA
  GGGATTGTAGAAACTTTTTATATTTTAGGAGCAAGTTACTTTATTATCATGCTCCTAGCT
  TCACAATTCATTAAGCGTCCAAATGAGCAAGAGCTTGCAATTTTATCTTCTTCAGGGAAA
  GAAAAAACAGCCTCTTTGACGCAAGGAATGGCTGCAAATCAGGCTCTAAAAAGCAATCGG
  TTTTATATGCTTTGGATTATTTTCTTTATCAACATAGCTTGTGGTTTAGGCTTAATTTCA
  GCGGCATCGCCAATGGCACAGGAGATGGCTGGCTTGTCTACAAGTCATGCAGCAGTAATG
  GTGGGTGTTTTGGGGATTTTCAATGGATTTGGTCGCTTGCTCTGGGCGAGTTTGTCTGAC
  TATATCGGTCGCCCTCTAACCTTTAGTAGACTTGTTCGGTAA
  60
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  882
  

⊟Protein

⊟General

• locus tag: SP70585_1629 [new locus tag: SP70585_RS08065 ]
• symbol: SP70585_1629
• description: oxalate:formate antiporter
• length: 293
• theoretical pI: 9.98134
• theoretical MW: 31603.1
• GRAVY: 0.674061

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids oxalate/formate antiporter family transporter (TIGR00890; HMM-score: 187.3)
  and 7 more
  oxalate/formate antiporter (TIGR04259; HMM-score: 148.4)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 48.4)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids monocarboxylate transporter (TIGR00892; HMM-score: 41.6)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 26.2)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 23.2)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids polyol permease (TIGR00897; HMM-score: 19.2)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, sialate:H+ symporter (SHS) family (TIGR00891; HMM-score: 17.6)
• TheSEED  :
  • Major facilitator:Oxalate:Formate Antiporter
• PFAM:
  MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 105.9)
  and 1 more
  Sugar_tr; Sugar (and other) transporter (PF00083; HMM-score: 23.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 8
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0.0001
  • Cytoplasmic Membrane Score: 0.9993
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0007
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.216552
  • TAT(Tat/SPI): 0.002539
  • LIPO(Sec/SPII): 0.035967
• predicted transmembrane helices (TMHMM): 8

⊟Accession numbers

• GI:
• RefSeq: ACO17751 NCBI
• UniProt: C1C8H8 UniProt

⊟Protein sequence

• MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVAFAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYLAYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGVGIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKSNRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWASLSDYIGRPLTFSRLVR

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SP70585_1627 < SP70585_1628 < SP70585_1629

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1414 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications