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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 07-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS03395 [old locus tag: SPAP_0684 ]
  • pan locus tag?: PNEUPAN001651000
  • symbol: SPAP_RS03395
  • pan gene symbol?: glnH3
  • synonym:
  • product: cysteine ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS03395 [old locus tag: SPAP_0684 ]
  • symbol: SPAP_RS03395
  • product: cysteine ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 657285..658151
  • length: 867
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014494 (657285..658151) NCBI
  • BioCyc: SPAP_RS03395 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0615 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAACTATTCAAACCACTCTTAACTGTTTTAGTACTTGCCTTTGCCCTTATCTTTATC
    ACTGCTTGTAGCTCAGGTGGAAACGCTGGTTCATCCTCTGGAAAAACAACTGCCAAAGCT
    CGCACTATCGATGAAATCAAAAAAAGCGGTGAACTGCGAATCGCCGTGTTTGGAGATAAA
    AAACTGTTTGGCTACGTTGACAATGATGGTTCTTACCAAGGCTACGATATTGAACTAGGG
    AACCAACTAGCTCAAAACCTTGGTGTCAAGGTTAAATACATTTCAGTCGATGCTGCCAAC
    CGTGCGGAATACTTGATTTCAAACAAGGTAGATATTATTCTTGCTAACTTTACAGTAACT
    GACGAACGTAAGAAACAAGTTGATTTTGCCCTTCCATATATGAAAGTTTCTCTGGGTGTC
    GTATCACCTAAGACTGGTCTCATTACAGACGTCAAACAACTTGAAGGTAAAACCTTAATT
    GTCACAAAAGGAACGACTGCTGAGACTTATTTTGAAAAGAATCATCCAGAAATCAAACTC
    CAAAAATACGACCAATACAGTGACTCTTACCAAGCTCTTCTTGACGGACGTGGAGATGCC
    TTTTCAACTGATAATACGGAAGTTCTAGCTTGGGCGCTTGAAAATAAAGGATTTGAAGTA
    GGAATTACTTCCCTCGGTGATCCCGATACCATTGCGGCAGCAGTTCAAAAAGGCAACCAA
    GAATTGCTAGACTTCATCAATAAAGATATTGAAAAATTAGGCAAGGAAAACTTCTTCCAC
    AAGGCCTATGAAAAAACACTTCACCCAACCTACGGTGACACTGCTAAAGCAGATGACCTG
    GTTGTTGAAGGTGGAAAAGTTGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    867

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_RS03395 [old locus tag: SPAP_0684 ]
  • symbol: SPAP_RS03395
  • description: cysteine ABC transporter substrate-binding protein
  • length: 288
  • theoretical pI: 5.24366
  • theoretical MW: 31516.5
  • GRAVY: -0.248611

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 125.7)
    and 6 more
    extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 54.8)
    Metabolism Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 43.2)
    glycosyl amidation-associated protein WbuZ (TIGR03572; HMM-score: 12.4)
    Metabolism Transport and binding proteins Other ABC transporter, substrate-binding protein, aliphatic sulfonates family (TIGR01728; HMM-score: 11.9)
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus protein, YscR/HrcR family (TIGR01102; HMM-score: 11.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus protein, YscR/HrcR family (TIGR01102; HMM-score: 11.5)
  • TheSEED: see SPAP_0684
  • ⊞PFAM:
    PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 161.7)
    and 4 more
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 36.5)
    Hybrid (CL0105) Biotin_lipoyl; Biotin-requiring enzyme (PF00364; HMM-score: 14.6)
    PBP (CL0177) OpuAC; Substrate binding domain of ABC-type glycine betaine transport system (PF04069; HMM-score: 14.1)
    no clan defined ODV-E18; Occlusion-derived virus envelope protein ODV-E18 (PF10717; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • ⊞SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
    • SP(Sec/SPI): 0.002345
    • TAT(Tat/SPI): 0.000244
    • LIPO(Sec/SPII): 0.997227
    • Cleavage Site: CS pos: 22-23. ITA-CS. Pr: 0.9975
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000765268 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKLFKPLLTVLVLAFALIFITACSSGGNAGSSSGKTTAKARTIDEIKKSGELRIAVFGDKKLFGYVDNDGSYQGYDIELGNQLAQNLGVKVKYISVDAANRAEYLISNKVDIILANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLIVTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGFEVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDTAKADDLVVEGGKVD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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