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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: SPAT_1252 [new locus tag: EL263_RS06590 ]
  • pan locus tag?: PNEUPAN002698000
  • symbol: mtaD
  • pan gene symbol?: trzA
  • synonym:
  • product: 5-methylthioadenosine/S-adenosylhomocysteine

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAT_1252 [new locus tag: EL263_RS06590 ]
  • symbol: mtaD
  • product: 5-methylthioadenosine/S-adenosylhomocysteine
  • replicon: chromosome
  • strand: -
  • coordinates: 1246762..1248273
  • length: 1512
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGAAAATCAAAGAGCAAACTAGGAAGCTAGCCGTAGGTTGCTCAAAGCACAGCTTTGAG
    GTTGTAGATAAGACTGACGAAGTCAGTTCAAAACACTGTTTTGAGGTTGCAGATAGAACT
    GACGAAGTCAGCTCAAAACACTGTTTTGAGGTTGCAGATAGAACTGACGAAGTCAGTAAC
    CACACCTACGGCAAAGTGAATCTGAAGTGGTTTGAAGAGAGTACAACTTGTCTTTTAGAA
    AAGGAGCCTATAATGAAAGTCTTTCAGCATGTAAATATCGTGACTTGTGATCAAGATTTC
    CATGTTTATCTTGATGGAATCTTAGCAGTCAAGGATTCTCAAATCGTCTATGTCGGTCAA
    GATAAGCCAGCGTTTTTAGAGCAAGCTGAGCAGATTATAGACTATCAGGGAGCTTGGATT
    ATGCCTGGTTTGGTCAATTGTCACACCCATTCTGCAATGACAGGTCTGAGAGGGATCCGA
    GATGACAGCAATCTCCATGAATGGCTCAATGACTATATTTGGCCAGCAGAATCTGAGTTT
    ACTCCCGACATGACTACCAATGCGGTCAAAGAAGCCCTGACAGAGATGCTCCAGTCAGGA
    ACAACAACCTTTAACGATATGTATAATCCCAATGGTGTGGATATCCAGCAAATTTATCAG
    GTGGTGAAAACTTCCAAGATGCGTTGTTATTTTTCTCCGACTCTCTTTTCTTCAGAGACA
    GAAACAACTGCTGAGACTATAAGTAGAACTCGATCCATCATAGACGAAATCTTAAAATAT
    AAAAATCCAAATTTCAAGGTTATGGTAGCACCTCATTCTCCGTATAGCTGCAGTAGAGAC
    TTGCTGGAAGCGAGTTTGGAAATGGCAAAAGAGCTAAATATTCCGCTCCATGTCCATGTG
    GCGGAGACCAAGGAGGAGTCAGGAATTATCCTCAAACGATACGGCAAACGCCCCCTTGCT
    TTTCTTGAAGAACTGGGTTATTTAGATCATCCGTCCGTATTTGCTCACGGGGTCGAATTA
    AACGAGAGAGAAATTGAACGCTTGGCATCTTCTCAAGTGGCTATCGCCCACAATCCTATC
    AGTAACCTCAAACTGGCATCAGGAATTGCTCCAATTATCCAGCTCCAAAAAGCGGGAGTA
    GCAGTCGGAATTGCGACTGACTCGGTTGCTTCCAATAACAATCTAGATATGTTTGAGGAA
    GGAAGGACTGCAGCTCTTCTTCAGAAGATGAAAAGTGGGGATGCCAGCCAGTTTCCAATC
    GAAACAGCTCTCAAGGTACTGACAATCGAAGGGGCTAAGGTCCTTGGAATGGAAAATCAG
    ATAGGAAGTCTGGAAGTCGGCAAGCAAGCAGATTTTCTGGTCATTCAACCACAAGGGAAA
    ATTCATCTCCAACCTCAGGAAAATATGCTGTCTCACCTGGTTTATGCAGTTAAATCTAGT
    GATGTAGATGATGTTTATATCGCCGGAGAACAGGTTGTTAAGCAAGGTCAAGTCCTGACA
    GTAGAACTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1512

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAT_1252 [new locus tag: EL263_RS06590 ]
  • symbol: MtaD
  • description: 5-methylthioadenosine/S-adenosylhomocysteine
  • length: 503
  • theoretical pI: 4.96128
  • theoretical MW: 56184.5
  • GRAVY: -0.249503

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other guanine deaminase (TIGR02967; EC 3.5.4.3; HMM-score: 189.4)
    putative selenium metabolism protein SsnA (TIGR03314; HMM-score: 152.6)
    and 12 more
    Metabolism Energy metabolism Amino acids and amines formiminoglutamate deiminase (TIGR02022; EC 3.5.3.13; HMM-score: 135.3)
    Metabolism Energy metabolism Amino acids and amines imidazolonepropionase (TIGR01224; EC 3.5.2.7; HMM-score: 69.1)
    allantoinase (TIGR03178; EC 3.5.2.5; HMM-score: 44.1)
    Metabolism Energy metabolism Other phosphonate metabolism protein PhnM (TIGR02318; HMM-score: 39.6)
    dihydropyrimidinase (TIGR02033; EC 3.5.2.2; HMM-score: 34.6)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis dihydroorotase, multifunctional complex type (TIGR00857; EC 3.5.2.3; HMM-score: 28.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine deaminase (TIGR01178; EC 3.5.4.2; HMM-score: 27.3)
    Metabolism Central intermediary metabolism Amino sugars N-acetylglucosamine-6-phosphate deacetylase (TIGR00221; EC 3.5.1.25; HMM-score: 25.8)
    formylmethanofuran dehydrogenase subunit A (TIGR03121; EC 1.2.99.5; HMM-score: 25.4)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides beta-aspartyl peptidase (TIGR01975; EC 3.4.19.5; HMM-score: 23.2)
    Metabolism Central intermediary metabolism Nitrogen metabolism urease, alpha subunit (TIGR01792; EC 3.5.1.5; HMM-score: 17.3)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions conjugative transfer region lipoprotein, TIGR03751 family (TIGR03751; HMM-score: 13.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Amidohydrolase (CL0034) Amidohydro_1; Amidohydrolase family (PF01979; HMM-score: 231)
    and 2 more
    Amidohydro_3; Amidohydrolase family (PF07969; HMM-score: 82.5)
    TatD_DNase; TatD related DNase (PF01026; HMM-score: 22.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02193
    • TAT(Tat/SPI): 0.000816
    • LIPO(Sec/SPII): 0.003739
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG39301 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKIKEQTRKLAVGCSKHSFEVVDKTDEVSSKHCFEVADRTDEVSSKHCFEVADRTDEVSNHTYGKVNLKWFEESTTCLLEKEPIMKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQAEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTTNAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTAETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAETKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPISNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQFPIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYAVKSSDVDDVYIAGEQVVKQGQVLTVEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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