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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_1154 [new locus tag: SPCG_RS13370 ]
  • pan locus tag?: PNEUPAN002273000
  • symbol: SPCG_1154
  • pan gene symbol?: serB
  • synonym:
  • product: phosphoserine phosphatase, truncation

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_1154 [new locus tag: SPCG_RS13370 ]
  • symbol: SPCG_1154
  • product: phosphoserine phosphatase, truncation
  • replicon: chromosome
  • strand: -
  • coordinates: 1140024..1140182
  • length: 159
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    GTGGCAATCGGTGATGGGGTCAATAATCTATTAATGTTGAAGTCGGCGGAGTTAGGAATC
    GCCTTTTGTTCCAAAGAAATGCTCAAAAAAGAAATACCACATCATGTTGACAAGAGGGAT
    TTTTTAGAAGTTCTTCCTTTGATTGACTGTTTAGAATGA
    60
    120
    159

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_1154 [new locus tag: SPCG_RS13370 ]
  • symbol: SPCG_1154
  • description: phosphoserine phosphatase, truncation
  • length: 52
  • theoretical pI: 4.91983
  • theoretical MW: 5838.94
  • GRAVY: 0.223077

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 41.4)
    and 6 more
    HAD ATPase, P-type, family IC (TIGR01494; EC 3.6.3.-; HMM-score: 21.7)
    Unknown function Enzymes of unknown specificity Cof-like hydrolase (TIGR00099; HMM-score: 17.2)
    phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein (TIGR02137; EC 3.1.3.3; HMM-score: 14.7)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cadmium-translocating P-type ATPase (TIGR01512; EC 3.6.3.3; HMM-score: 14.2)
    heavy metal translocating P-type ATPase (TIGR01525; EC 3.6.3.-; HMM-score: 12.1)
    Metabolism Transport and binding proteins Cations and iron carrying compounds calcium-translocating P-type ATPase, SERCA-type (TIGR01116; EC 3.6.3.8; HMM-score: 10.7)
  • TheSEED  :
    • Phosphoserine phosphatase (EC 3.1.3.3)
    Amino Acids and Derivatives Alanine, serine, and glycine Glycine and Serine Utilization  Phosphoserine phosphatase (EC 3.1.3.3)
    and 1 more
    Amino Acids and Derivatives Alanine, serine, and glycine Serine Biosynthesis  Phosphoserine phosphatase (EC 3.1.3.3)
  • PFAM:
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 14.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014771
    • TAT(Tat/SPI): 0.002095
    • LIPO(Sec/SPII): 0.029614
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVLPLIDCLE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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