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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 02-FEB-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae D39
- locus tag: SPD_RS07480 [old locus tag: SPD_1407 ]
- pan locus tag?: PNEUPAN002961000
- symbol: SPD_RS07480
- pan gene symbol?: apt
- synonym:
- product: adenine phosphoribosyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPD_RS07480 [old locus tag: SPD_1407 ]
- symbol: SPD_RS07480
- product: adenine phosphoribosyltransferase
- replicon: chromosome
- strand: -
- coordinates: 1426254..1426766
- length: 513
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_008533 (1426254..1426766) NCBI
- BioCyc:
- MicrobesOnline: see SPD_1407
- PneumoBrowse for strain D39V: SPV_1407 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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421
481ATGAATTTAAAAGATTACATTGCAACAATTGAAAATTATCCAAAGGAAGGCATTACCTTC
CGTGATATTAGTCCTTTGATGGCTGATGGAAATGCTTATAGCTACGCTGTTCGTGAAATC
GTTCAGTATGCTACTGACAAGAAAGTCGACATGATCGTGGGACCTGAAGCTCGTGGATTT
ATCGTGGGTTGTCCAGTTGCCTTTGAGTTGGGAATTGGTTTTGCGCCTGTTCGTAAGCCA
GGTAAATTGCCACGCGAAGTTATTTCTGCTGACTATGAAAAAGAGTACGGTGTCGATACC
TTGACTATGCACGCGGATGCCATTAAGCCAGGTCAACGTGTTCTTATTGTAGATGACCTT
TTGGCGACAGGTGGAACTGTTAAGGCAACTATCGAGATGATTGAAAAACTTGGTGGTGTT
ATGGCAGGTTGTGCCTTCCTTGTTGAATTGGATGAATTGAACGGCCGTGAAAAAATTGGT
GACTACGACTACAAAGTTCTTATGCATTATTAA60
120
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480
513
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPD_RS07480 [old locus tag: SPD_1407 ]
- symbol: SPD_RS07480
- description: adenine phosphoribosyltransferase
- length: 170
- theoretical pI: 4.63646
- theoretical MW: 18728.6
- GRAVY: -0.0152941
⊟Function[edit | edit source]
- reaction: EC 2.4.2.7? ExPASyAdenine phosphoribosyltransferase AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine phosphoribosyltransferase (TIGR01090; EC 2.4.2.7; HMM-score: 224.8)and 9 morePurines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis pur operon repressor PurR (TIGR01743; HMM-score: 47.4)Regulatory functions DNA interactions pur operon repressor PurR (TIGR01743; HMM-score: 47.4)Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 40.6)Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR00336; EC 2.4.2.10; HMM-score: 36.2)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides xanthine phosphoribosyltransferase (TIGR01744; EC 2.4.2.22; HMM-score: 36)Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis ribose-phosphate diphosphokinase (TIGR01251; EC 2.7.6.1; HMM-score: 19.9)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uracil phosphoribosyltransferase (TIGR01091; EC 2.4.2.9; HMM-score: 18.7)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 17.9)Cellular processes DNA transformation comF family protein (TIGR00201; HMM-score: 14.3)
- TheSEED: see SPD_1407
- PFAM: PRTase-like (CL0533) Pribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 59)and 2 moreUPRTase; Uracil phosphoribosyltransferase (PF14681; HMM-score: 18.3)PRTase_2; Phosphoribosyl transferase (PF15609; HMM-score: 12.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 10
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.013965
- TAT(Tat/SPI): 0.000438
- LIPO(Sec/SPII): 0.001119
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYATDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIGDYDYKVLMHY
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1407 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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