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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_0461 [new locus tag: SPG_RS13180 ]
  • pan locus tag?: PNEUPAN000272000
  • symbol: SPG_0461
  • pan gene symbol?: hsdS
  • synonym:
  • product: Type I restriction modification DNA specificity domain

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_0461 [new locus tag: SPG_RS13180 ]
  • symbol: SPG_0461
  • product: Type I restriction modification DNA specificity domain
  • replicon: chromosome
  • strand: -
  • coordinates: 454332..455426
  • length: 1095
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001015 (454332..455426) NCBI
  • BioCyc:
  • MicrobesOnline: 5755730 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGACACCAGAACAACTTAAAGCAAGTATTCTCCAAAGAGCGATGGAAGGGAAATTAGTG
    CCGCAAAATCCCAATGACGAACCTGCAAGTGAATTATTAAAGAGAATTAAAGCTGAAAAA
    GAAAAACTTATCAGTGAAGGAAAAATCAAACGAGATAAAAAGGAAACTGAGATATTTCGT
    GGTGATGATGGGAAACATTATGGGAAGTTTGCTGATGGAAGCACTCAAGAAATTGATGTT
    CCTTATGATATTCCTGATACTTGGGAGTGGGTGAGGATTTCTACATTGGTTGAAATTGTC
    AGAGGTGGCTCTCCACGACCAATCAAAGATTATCTTACTTCTGAAGTAGATGGAATAAAT
    TGGATAAAAATAGGTGATACTGAAAAGGGTGAAAAGTATATAAATAATGTTAAAGAAAAA
    ATCAAAAAATCAGGACTTAACAAAACTAGATTTGTAAAAAAAGGTACATTTTTGTTAACT
    AATTCTATGAGTTTTGGTAGACCTTATATTTTGAATGTTGATGGTGCAATACACGATGGA
    TGGTTGGCTATTTCGAACTATGAAAACTCATTAAATAAAGATTACCTATTCTATATTCTT
    TCATCAAATGTAGTTTATTCTCAATTTCTATCTCTAATTAGTGGAGCTGTTGTGAAAAAC
    TTGAATAGTGATAAAGTTGCTTCTATTCTTATCCCTCTCCCCCCACTATCCGAACAACAA
    CGCATAATAGAAGCAATCGAATCAGCTTTAGAAAAAGTAGATGAATATGCTGAAAGTTAT
    AATAGACTAGAACAGCTAGATAAAGAATTTCCAGATAAACTAAAAAAATCTATTCTTCAA
    TATGCTATGCAAGGAAAATTAGTTGAACAAGACCCAAATGATGAATCAGTCGAAGTTTTA
    CTTGAAAAAATACGAGCAGAAAAACAAAAACTCTTTGAAGAAGGCAAGATTAAAAAGAAA
    GATTTGGACATTTCTATTGTTTCCCAAGGAGATGATAACTCTTATTATGGGAATATACCT
    ATGAATTGGGTTGTTATAAAAATAAAAGATATTTTTTCAATGAATACAGGTCTTTCTTGG
    CGATTTAAGCATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1095

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_0461 [new locus tag: SPG_RS13180 ]
  • symbol: SPG_0461
  • description: Type I restriction modification DNA specificity domain
  • length: 364
  • theoretical pI: 6.35693
  • theoretical MW: 41615.3
  • GRAVY: -0.55

⊟Function[edit | edit source]

  • TIGRFAM:
    putative Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase, subunit C (TIGR01827; HMM-score: 16.5)
  • TheSEED  :
    • Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)
    DNA Metabolism DNA Metabolism - no subcategory Restriction-Modification System  Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)
    and 1 more
    DNA Metabolism DNA Metabolism - no subcategory Type I Restriction-Modification  Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)
  • PFAM:
    TRD (CL0477) Methylase_S; Type I restriction modification DNA specificity domain (PF01420; HMM-score: 59)
    and 6 more
    no clan defined DUF6291; Family of unknown function (DUF6291) (PF19808; HMM-score: 13.3)
    TIM_barrel (CL0036) NanE; Putative N-acetylmannosamine-6-phosphate epimerase (PF04131; HMM-score: 13.1)
    no clan defined Flagellin_C; Bacterial flagellin C-terminal helical region (PF00700; HMM-score: 13)
    MACRO (CL0223) Peptidase_M17_N; Cytosol aminopeptidase family, N-terminal domain (PF02789; HMM-score: 12.7)
    NOG1_N (CL0669) DUF4168; Domain of unknown function (DUF4168) (PF13767; HMM-score: 11.7)
    no clan defined ATP-cone; ATP cone domain (PF03477; HMM-score: 8.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.6562
    • Cytoplasmic Membrane Score: 0.0031
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.3402
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005342
    • TAT(Tat/SPI): 0.000647
    • LIPO(Sec/SPII): 0.001234
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF56019 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLISEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRISTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNIPMNWVVIKIKDIFSMNTGLSWRFKH

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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