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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_1142 [new locus tag: SPG_RS05755 ]
  • pan locus tag?: PNEUPAN002506000
  • symbol: SPG_1142
  • pan gene symbol?: mcrB
  • synonym:
  • product: putative endonuclease, point mutation

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_1142 [new locus tag: SPG_RS05755 ]
  • symbol: SPG_1142
  • product: putative endonuclease, point mutation
  • replicon: chromosome
  • strand: -
  • coordinates: 1122245..1123837
  • length: 1593
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    TTGGATCAGCGATTTTCAAAATTAAAATCAGATTTGTATGAAATTATCAAAGAAGGTATT
    CGTTTTAACTTTGAAAATTCTATTTTTGATATGAAAAGATCAACAAATGAATTTATTGGT
    CGTTCTGCTATGGTGACAAAATTACTTTGTATCTATTCTGAGGGAGATCCTTTCTTTGGT
    GTAAATATTAATAGTCAGAAAGAATTTTGGAACCACTTTGTTTCTCAGACAAATCAAGGT
    GGACCTTATCTGCAAAATCATAAAATAATTGAACTGGTGTCCAAAACTTATCCTGAGTTG
    GAGCCATCGAAATTAGGAACTATGCTTTTTGAGTATTCTAAGCTTTTTATGGAAAATAAG
    GAAGACAATAGTACAATGGATTCATCAAACAATTTTCGTCATCAATTAACTCAATCTCTA
    TTAAAGTCTCCAAACCTTATCCTTCGTGGTGCTCCTGGCACAGGAAAGACTTATCTTGCT
    AAAGAAATTGCCAAAGAATTAACGGATGGCAACGAAGACCAAATCGGATTTGTACAATTT
    CACCCATCCTATGATTATACGGATTTTGTAGAAGGTTTAAGACCAGTATCAAATGGGGAT
    GGAGCTATTGAGTTTAGGCTACAGGACGGTATTTTTAAAGATTTTTGTCAGAAAGCAAAA
    GAACCCCAATTGATTGGAGGACAAGATAATTTTGATGAGGCTTGGGATTCTTACTTAGAA
    TATATAAATGTTGCTGAAGAAAAAGAATATATAACAAAAACATCTTACTTATCTGTTAAT
    AGTAGACAAAATTTGTCAGTAAATTATGATAGTGGTGTTCCAGGATGGTCACTACCTAGC
    AAATATGTTTACGAGTTGTATAAAGATAAAAATTATAATAAGCAAGAATACTACAAAAGT
    GGTGGAAAAACTGTCCTAGAAACATTGAGAAAGAGATTTGGTTTGAAAGACTATGTTTCC
    CCAACAGAAATTGATACTGATAAGAAATTCGTCTTCATCATCGATGAAATCAATCGTGGG
    GAGATTTCTAAGATTTTTGGCGAACTCTTTTTCTCTATCGACCCTGGCTATCGTGGTGAA
    AAAGGAAGTGTTTCTACCCAATATGCAAATCTACACGAAACTGATGAAAAGTTCTATATC
    CCCGAAAATGTTTACATCATCGGAACTATGAATGATATTGATCGTTCAGTGGATACCTTT
    GATTTTGCTATGCGTCGTCGTTTTCGTTTTGTTGAAGTTACTGCCGAGGGTCAAGTTGGC
    ATGTTGGATAAAGAGCTGAATATCCATGCAGAAGAAGCAAAAATTCGTCTAAGAAACTTG
    AACGCTGCTATCGAAAATGTTCAGGAATTAAACAGTCATTATCATATTGGACCAAGTTAT
    TTTCTTAAGTTGAAGGATGTAGATTTTGACTATGAATTACTCTGGTCTGATTATATTAAG
    CCTCTCCTAGAAGACTACTTGCGAGGTTCTTATGATGAGGTTGAAACTTTGGAAACTTTG
    AAAAAAGCATTTGAACTGACAAATAATGAGCAAAAAGATCAGGCAGTAGCTGATGACAAT
    GAAGGTGATGAAAACGATGATGCGGATTACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1593

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_1142 [new locus tag: SPG_RS05755 ]
  • symbol: SPG_1142
  • description: putative endonuclease, point mutation
  • length: 530
  • theoretical pI: 4.51799
  • theoretical MW: 61441
  • GRAVY: -0.663208

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA aminoacylation L-seryl-tRNA(Sec) kinase (TIGR03574; EC 2.7.1.164; HMM-score: 16.5)
    26S proteasome subunit P45 family (TIGR01242; HMM-score: 15)
    P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 14.8)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair orc1/cdc6 family replication initiation protein (TIGR02928; HMM-score: 14.8)
    and 6 more
    Cellular processes Cellular processes Cell division ATP-dependent metallopeptidase HflB (TIGR01241; EC 3.4.24.-; HMM-score: 13.1)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides ATP-dependent metallopeptidase HflB (TIGR01241; EC 3.4.24.-; HMM-score: 13.1)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides proteasome ATPase (TIGR03689; EC 3.6.4.8; HMM-score: 12.8)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exodeoxyribonuclease V, alpha subunit (TIGR01447; EC 3.1.11.5; HMM-score: 11.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair Holliday junction DNA helicase RuvB (TIGR00635; EC 3.6.4.12; HMM-score: 10.7)
    AAA family ATPase, CDC48 subfamily (TIGR01243; HMM-score: 10.7)
  • TheSEED  :
    • Endonuclease
  • PFAM:
    P-loop_NTPase (CL0023) AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 53.1)
    and 26 more
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 26.8)
    NACHT; NACHT domain (PF05729; HMM-score: 21.8)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 21.1)
    AAA_14; AAA domain (PF13173; HMM-score: 20.1)
    AAA_18; AAA domain (PF13238; HMM-score: 19.4)
    AAA_22; AAA domain (PF13401; HMM-score: 16.5)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 16.3)
    TsaE; Threonylcarbamoyl adenosine biosynthesis protein TsaE (PF02367; HMM-score: 16.2)
    AAA_19; AAA domain (PF13245; HMM-score: 16.1)
    AAA_33; AAA domain (PF13671; HMM-score: 15)
    ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 14.8)
    Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 14.3)
    IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 14.2)
    AAA_30; AAA domain (PF13604; HMM-score: 13.8)
    Zeta_toxin; Zeta toxin (PF06414; HMM-score: 13.1)
    AAA_3; ATPase family associated with various cellular activities (AAA) (PF07726; HMM-score: 13)
    DUF2075; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 12.9)
    AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 12.7)
    Sigma54_activat; Sigma-54 interaction domain (PF00158; HMM-score: 12.6)
    RuvB_N; Holliday junction DNA helicase RuvB P-loop domain (PF05496; HMM-score: 12.4)
    NTPase_1; NTPase (PF03266; HMM-score: 11.8)
    AAA_25; AAA domain (PF13481; HMM-score: 11.8)
    DnaB_C; DnaB-like helicase C terminal domain (PF03796; HMM-score: 11.6)
    bpMoxR; MoxR domain in the MoxR-vWA-beta-propeller ternary systems (PF20030; HMM-score: 11.5)
    PhoH; PhoH-like protein (PF02562; HMM-score: 11.4)
    NB-ARC; NB-ARC domain (PF00931; HMM-score: 11.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.6303
    • Cytoplasmic Membrane Score: 0.1094
    • Cell wall & surface Score: 0.0092
    • Extracellular Score: 0.2511
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006363
    • TAT(Tat/SPI): 0.000629
    • LIPO(Sec/SPII): 0.000323
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF55487 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDQRFSKLKSDLYEIIKEGIRFNFENSIFDMKRSTNEFIGRSAMVTKLLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKLGTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKEPQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVADDNEGDENDDADY

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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