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serotype 19A
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serotype 14
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serotype 19F
Xen35
serotype 4
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serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_2065 [new locus tag: SPG_RS10345 ]
  • pan locus tag?: PNEUPAN003813000
  • symbol: SPG_2065
  • pan gene symbol?: tktN
  • synonym:
  • product: transketolase N-terminal section

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_2065 [new locus tag: SPG_RS10345 ]
  • symbol: SPG_2065
  • product: transketolase N-terminal section
  • replicon: chromosome
  • strand: -
  • coordinates: 1953628..1954485
  • length: 858
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATTTTAAGTAAAAATAGAGAAGATGAGTTAAGAAAATTTGCGACTAACATCCGATTA
    AATACTCTTAGAACATTGAATCATCTTGGATTCGGACATTACGGAGGAAGTCTGTCTATC
    GTAGAAGTTTTAGCAGTGCTTTATGGTGAAATAATGCCAATGACTCCAGAAATATTTGCA
    GCACGAGATAGAGATTATTTCATATTATCAAAAGGTCATGGAGGACCAGCTCTATACAGT
    ACACTCTATTTGAATGGTTTCTTTGACAAAGAATTCTTATATTCTTTAAATACAAATGGA
    ACCAAATTACCGTCTCATCCTGATAGAAATCTAACGCCAGGCATAGATATGACAACGGGC
    TCTTTAGGACAAGGAATTAGTGTTGCAACTGGACTTGCATATGGTCAGAGAATAAGAAAG
    AGTCCCTTTTATACTTATGCTATTGTTGGAGATGGTGAGTTAAATGAAGGACAATGTTGG
    GAGGCTATACAGTTTGCTTCTCATCAACAGTTATCCAACTTAATTGTATTTGTTGATGAG
    AACAAAAAACAATTAGATGGTTTTACAAAGGATATTTGTAATCCAGGTGATTTCGTAGAA
    AAATTTTCAGCATTTGGATTTGAATCCATTAGGGTCAAGGGTTCAGATATTAGAGAAATT
    TATGAAGGGATTGTCCAATTAAAACAGTCAAATAATTCATCACCTAAGTGCATTGTATTA
    GATACTATTAAAGGTCAAGGGGTTCAAGAGCTGGAAGAAATGAAATCCAATCATCATCTT
    CGCCCTACTGTAGAGGAGAAACAAATGTTAACTTCAGTTGTAGAAAGATTAAGTCAGGAA
    TTGGAGGAAACAGAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    858

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_2065 [new locus tag: SPG_RS10345 ]
  • symbol: SPG_2065
  • description: transketolase N-terminal section
  • length: 285
  • theoretical pI: 5.40909
  • theoretical MW: 31969
  • GRAVY: -0.338947

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Pentose phosphate pathway transketolase (TIGR00232; EC 2.2.1.1; HMM-score: 161.1)
    and 7 more
    Metabolism Energy metabolism Pyruvate dehydrogenase pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit (TIGR03182; EC 1.2.4.1; HMM-score: 52.4)
    pyruvate dehydrogenase (acetyl-transferring), homodimeric type (TIGR00759; EC 1.2.4.1; HMM-score: 46.6)
    Metabolism Energy metabolism Pyruvate dehydrogenase pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit (TIGR03181; EC 1.2.4.1; HMM-score: 39.1)
    alpha-ketoglutarate dehydrogenase (TIGR03186; HMM-score: 38.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other 1-deoxy-D-xylulose-5-phosphate synthase (TIGR00204; EC 2.2.1.7; HMM-score: 37.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine 1-deoxy-D-xylulose-5-phosphate synthase (TIGR00204; EC 2.2.1.7; HMM-score: 37.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridoxine 1-deoxy-D-xylulose-5-phosphate synthase (TIGR00204; EC 2.2.1.7; HMM-score: 37.5)
  • TheSEED  :
    • Transketolase, N-terminal section (EC 2.2.1.1)
    Carbohydrates Central carbohydrate metabolism Pentose phosphate pathway  Transketolase, N-terminal section (EC 2.2.1.1)
  • PFAM:
    THDP-binding (CL0254) Transketolase_N; Transketolase, thiamine diphosphate binding domain (PF00456; HMM-score: 155.8)
    and 4 more
    DXP_synthase_N; 1-deoxy-D-xylulose-5-phosphate synthase (PF13292; HMM-score: 44.2)
    E1_dh; Dehydrogenase E1 component (PF00676; HMM-score: 30.5)
    XFP_N; XFP N-terminal domain (PF09364; HMM-score: 23.4)
    TPP_enzyme_C; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain (PF02775; HMM-score: 20.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9797
    • Cytoplasmic Membrane Score: 0.0026
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0175
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009201
    • TAT(Tat/SPI): 0.003105
    • LIPO(Sec/SPII): 0.001271
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF55346 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVLAVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTKLPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCWEAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIREIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVERLSQELEETE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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