From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_0481 [new locus tag: SPH_RS02340 ]
  • pan locus tag?: PNEUPAN001209000
  • symbol: SPH_0481
  • pan gene symbol?: mapZ
  • synonym:
  • product: conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0481 [new locus tag: SPH_RS02340 ]
  • symbol: SPH_0481
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 435718..437130
  • length: 1413
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGAGTAAGAAAAGACGAAATCGTCATAAAAAAGAAGGTCAAGAACCGCAATTTGATTTT
    GATGAAGCAAAAGAGCTAACAGTTGGTCAAGCTATTCGTAAAAATGAAGAAGTGGAAGCA
    GGAGTCTTGCCTGAGGATTCCATTTTGGACAAGTATGTTAAACAACACAAAGATGAAATA
    GAAGCAGATAAGTTTGCGACTCGCCAATACAAAAAAGAGGAGCTAGTTGAAACTCAGAGT
    CTGGATGATTTAATTCAAGAGATGCGTGAGGCTGTAGAAGAGTCAGAAGCTTCTTCGGAG
    GAAGTTCCATCTTCTGAAGACATCTTACCACCCTTGCCTCTGGACGATGAGGAGCAAGGC
    TTGGATCCTCTATTGCTAGAGGATGAAAATCCAACAGAAATGACTGAAGAAGTGGAAGAG
    GAGCAAAACTTTTCTCGTCTGGAACAAGAAGACTCAGAAAAGAAAAGCAAAAAAGGCTTT
    GTTTTAACTGCTTTGGCGCTTGTATCAGTAATTATCTGTGTCAGTGCTTATTATGTCTAT
    CGTCAAGTGAATCGCTCGACCAAGGAAATTGAAACTTCTCAATCAACTACAGCCAATCAA
    TCGGATGTGGATGATTTTAATACACTTTATGACGCCTTCTACACAGACAGCAATAAAACG
    GCTTTGAAAAATAGTCAGTTTGATAAACTAAGTCAACTCAAGACCTTACTTGATAAGCTG
    GAAGGTAGTCGTGAGCATACGCTTGCCAAATCTAAATATGATAGTCTAGCAACGCAAATC
    AAGGCCATTCAAGATGTCAATGCACAATTTGAAAAACCAGCTATTGTGGATGGTGTGTTG
    GATACCAATGCCAAAACCAAATCGGATGCTAAATTTACAGATATTAAAACTGGAAATACG
    GAGCTTGATAAAGTTCTAGATAAGGCTATCAGCCTTGGTAAGAGCCAGCAAACAAGTACT
    TCTAGCTCTAGCTCAAGTTCAAGTCAAACTAGTAGCTCAAGTTCAAGTCAAGCAAGCTCA
    AATACGACTAGTGAGACAAGCCCAAGTAGTTCAAATGCTGCCTCAAATGAGACTAGAAGT
    TCTCGTAGCGAAGTCAATATGGGCGTATCAAGTGCAGGGGTTGCTGTTCAAAGAAGTGCT
    AGTCGTGTTGCCTATAATCAGTCTGCTATTGATGATAGTAACAACTCTGCTTGGGATTTT
    GCGGATGGTGTCTTGGAACAAATTCTAGCGACTTCACGTTCACGTGGCTATATCACTGGA
    GACCAATATATCCTTGAACGTGTCAATATCGTTAATGGCAATGGTTATTACAACCTCTAC
    AAGCCAGATGGAACCTATCTCTTTACCCTTAACTGTAAGACAGGCTACTTTGTCGGAAAT
    GGCGCTGGTCATGCGGATGACTTGGACTACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1413

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_0481 [new locus tag: SPH_RS02340 ]
  • symbol: SPH_0481
  • description: conserved hypothetical protein
  • length: 470
  • theoretical pI: 4.33242
  • theoretical MW: 52010.3
  • GRAVY: -0.779362

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Hypothetical protein SPy1643
  • PFAM:
    no clan defined MapZ_EC1; MapZ extracellular domain 1 (PF18041; HMM-score: 114.6)
    MapZ_C2; MapZ extracellular C-terminal domain 2 (PF18708; HMM-score: 106.3)
    and 8 more
    TPR (CL0020) DUF6377; Domain of unknown function (DUF6377) (PF19904; HMM-score: 17.3)
    no clan defined DUF6550; Family of unknown function (DUF6550) (PF20187; HMM-score: 16.1)
    Otopetrin; Otopetrin (PF03189; HMM-score: 15.5)
    DUF515; Protein of unknown function (DUF515) (PF04415; HMM-score: 13.2)
    RNase_H (CL0219) DDE_Tnp_IS240; DDE domain (PF13610; HMM-score: 13.2)
    no clan defined Vpu; Vpu protein (PF00558; HMM-score: 12.7)
    Orf78; Orf78 (ac78) (PF06024; HMM-score: 10.4)
    SCIMP; SCIMP protein (PF15050; HMM-score: 9.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9838
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.0154
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006238
    • TAT(Tat/SPI): 0.000747
    • LIPO(Sec/SPII): 0.000878
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLPEDSILDKYVKQHKDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEVPSSEDILPPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNFSRLEQEDSEKKSKKGFVLTALALVSVIICVSAYYVYRQVNRSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSNKTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIVDGVLDTNAKTKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSSSQTSSSSSSQASSNTTSETSPSSSNAASNETRSSRSEVNMGVSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGHADDLDY

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Aurore Fleurie, Christian Lesterlin, Sylvie Manuse, Chao Zhao, Caroline Cluzel, Jean-Pierre Lavergne, Mirita Franz-Wachtel, Boris Macek, Christophe Combet, Erkin Kuru, Michael S VanNieuwenhze, Yves V Brun, David Sherratt, Christophe Grangeasse
MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae.
Nature: 2014, 516(7530);259-262
[PubMed:25470041] [WorldCat.org] [DOI] (I p)

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPH_0481&oldid=11429"