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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1347 [new locus tag: SPH_RS06525 ]
  • pan locus tag?: PNEUPAN002472000
  • symbol: SPH_1347
  • pan gene symbol?: panT
  • synonym:
  • product: integral membrane protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1347 [new locus tag: SPH_RS06525 ]
  • symbol: SPH_1347
  • product: integral membrane protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1248164..1248727
  • length: 564
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGAAAAAACGCTCTAATATTGCACCCATTGCTATCTTTTTTGCTACCATGCTCGTGATA
    CACTTTCTGAGCTCACTTATCTTTAACCTTTTTCCATTTCCAATCAAACCGACCATTGTT
    CATATTCCTGTCATTATTGCCAGCATTATTTATGGTCCACGAGTTGGGGTTACACTTGGA
    TTTTTGATGGGATTACTTAGCTTGACGGTTAACACGATTACGATTCTACCGACAAGCTAC
    CTCTTCTCTCCCTTCGTACCAAACGGAAACATCTACTCAGCTATCATTGCCATTGTCCCA
    CGTATTTTGATTGGTTTAACTCCTTACTTAGTCTATAAACTGATGAAAAACAAGACTGGT
    CTGATTTTAGCTGGGGCCCTTGGTTCCTTGACAAATACTATCTTTGTCCTTGGAGGAATC
    TTCTTCCTATTTGGAAATGTTTATAATGGAAATATCCAACTTCTTCTGGCAACCGTTATC
    TCAACAAATTCAATTGCTGAATTGGTCATTTCTGCAATTCTAACCCTAGCCATTGTTCCA
    CGACTACAAACCTTGAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    564

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1347 [new locus tag: SPH_RS06525 ]
  • symbol: SPH_1347
  • description: integral membrane protein
  • length: 187
  • theoretical pI: 10.9425
  • theoretical MW: 20272.6
  • GRAVY: 1.11337

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other energy-coupled thiamine transporter ThiT (TIGR02357; HMM-score: 20.5)
    and 3 more
    Metabolism Transport and binding proteins Unknown substrate ECF transporter S component, folate family (TIGR04518; HMM-score: 14.5)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan rod shape-determining protein MreD (TIGR03426; HMM-score: 13.1)
    Cellular processes Cellular processes Sporulation and germination stage II sporulation protein E (TIGR02865; EC 3.1.3.16; HMM-score: 7.1)
  • TheSEED  :
    • Pantothenate ECF transporter, substrate-specific component PanT
    Cofactors, Vitamins, Prosthetic Groups, Pigments Coenzyme A Coenzyme A Biosynthesis  Substrate-specific component PanT of predicted pantothenate ECF transporter
    and 1 more
    Membrane Transport Membrane Transport - no subcategory ECF class transporters  Substrate-specific component PanT of predicted pantothenate ECF transporter
  • PFAM:
    Gx_transp (CL0315) ECF_trnsprt; ECF transporter, substrate-specific component (PF12822; HMM-score: 68.4)
    and 2 more
    Thia_YuaJ; Thiamine transporter protein (Thia_YuaJ) (PF09515; HMM-score: 23.2)
    ThrE (CL0470) ThrE; Putative threonine/serine exporter (PF06738; HMM-score: 6.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9977
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0022
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.012396
    • TAT(Tat/SPI): 0.000347
    • LIPO(Sec/SPII): 0.02502
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPVIIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRILIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVISTNSIAELVISAILTLAIVPRLQTLKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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