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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS06950 [old locus tag: SPH_1438 ]
  • pan locus tag?: PNEUPAN002591000
  • symbol: SPH_RS06950
  • pan gene symbol?: aroH
  • synonym:
  • product: chorismate mutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS06950 [old locus tag: SPH_1438 ]
  • symbol: SPH_RS06950
  • product: chorismate mutase
  • replicon: chromosome
  • strand: -
  • coordinates: 1331653..1331919
  • length: 267
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (1331653..1331919) NCBI
  • BioCyc: SPH_RS06950 BioCyc
  • MicrobesOnline: see SPH_1438
  • PneumoBrowse for strain D39V: SPV_1151 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGGATTTAGATATTATTCGTCAAGAAATCGATCAAATCGACGACCAAATTGTCAAACTG
    TTAGAAGAACGAATGCACTTAGTTGAAGGAGTTGTCGCTTATAAGAAGGCTTCAGGGAAA
    CCGATTTTAGATACTAAGAGAGAAGCAGTTATTTTTGAAAAGGTTAGAAGTCGTGTAGAG
    GACAAGCGCTATCAGGAGACTATTGTCGCGACTTTTTCGGACATACTCAAACGTTCGCGT
    GATTATCAGGATCAAAATATCAAATGA
    60
    120
    180
    240
    267

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS06950 [old locus tag: SPH_1438 ]
  • symbol: SPH_RS06950
  • description: chorismate mutase
  • length: 88
  • theoretical pI: 5.92905
  • theoretical MW: 10421.9
  • GRAVY: -0.629545

⊟Function[edit | edit source]

  • reaction:
    EC 5.4.99.5?  ExPASy
    Chorismate mutase Chorismate = prephenate
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01805; EC 5.4.99.5; HMM-score: 125.9)
    and 10 more
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01791; EC 5.4.99.5; HMM-score: 48.2)
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01807; EC 5.4.99.5; HMM-score: 39.7)
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01801; EC 5.4.99.5; HMM-score: 39.3)
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01797; EC 5.4.99.5; HMM-score: 38.2)
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01808; EC 5.4.99.5; HMM-score: 37.7)
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01799; EC 5.4.99.5; HMM-score: 37.6)
    Metabolism Amino acid biosynthesis Aromatic amino acid family putative chorismate mutase (TIGR01806; EC 5.4.99.5; HMM-score: 36.5)
    Metabolism Amino acid biosynthesis Aromatic amino acid family chorismate mutase (TIGR01795; EC 5.4.99.5; HMM-score: 29.6)
    chorismate mutase related enzymes (TIGR01803; HMM-score: 29.2)
    CRISPR type III-A/MTUBE-associated protein Csm2 (TIGR01870; HMM-score: 20.3)
  • TheSEED: see SPH_1438
  • PFAM:
    no clan defined CM_2; Chorismate mutase type II (PF01817; HMM-score: 76.7)
    and 2 more
    BEN; BEN domain (PF10523; HMM-score: 14.8)
    Osmo_CC; Osmosensory transporter coiled coil (PF08946; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9958
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.003
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002669
    • TAT(Tat/SPI): 0.00065
    • LIPO(Sec/SPII): 0.000418
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILDTKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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