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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae JJA
- locus tag: SPJ_0159 [new locus tag: SPJ_RS00785 ]
- pan locus tag?: PNEUPAN000803000
- symbol: SPJ_0159
- pan gene symbol?: tsaB
- synonym:
- product: glycoprotein endopeptidase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPJ_0159 [new locus tag: SPJ_RS00785 ]
- symbol: SPJ_0159
- product: glycoprotein endopeptidase
- replicon: chromosome
- strand: +
- coordinates: 143439..144122
- length: 684
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: CP000919 (143439..144122) NCBI
- BioCyc: see SPJ_RS00785
- MicrobesOnline: 7478440 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0134 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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661ATGAAAGTATTAGCTTTTGATACGTCCAGCAAGGCTCTTTCTCTGGCTATTTTAGAGGAT
AAGCAGGTTCTTGCCGAGACGACGATTAATATTAAGAAAAATCACAGTATTACTCTTATG
CCTGCCATCGATTTTTTGATGGCAAGTTTGGATTGGACACCCAAGGATTTGGACCGAATC
GTGGTAGCTGAAGGGCCGGGTAGCTATACAGGCTTGCGAATTGCGGTAGCAACTGCTAAG
ACCTTAGCTTACACCCTGAACATCGAGTTGGTTGGTATGTCGAGTCTCTTGGCTCTGGTG
CCCCACCAACAAGAAGGTTTGTTTGTCCCCTTGATGGATGCGCGTCGCAATAATGTTTAT
GCAGGATTTTATGAAAATGCCAAACCTGTCATGGCAGAAGCGCACCTATCTTTTGAAGAG
GTGCTAGAAAAAGTCAAGGGTACTAGTCAGGTAACCTTTGTCGGAGAAGTTGGCCCCTTT
GTTGAGCAGATTCAAAAACACTTGCCAAGGACTGATTACAAAGAAACATTGCCCAATGCA
GCCAATCTTGCTCTTTTAGCTTGGGACAAGGAAGCAGACTCCTTGCATGATTTTGTGCCG
AATTACCTCAAACGAGTCGAGGCTGAGGAAAACTGGCTCAAGAACCATACCGAGTCTGGT
GAGTCCTACATTAAACGCCTATGA60
120
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684
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPJ_0159 [new locus tag: SPJ_RS00785 ]
- symbol: SPJ_0159
- description: glycoprotein endopeptidase
- length: 227
- theoretical pI: 5.35216
- theoretical MW: 25314.9
- GRAVY: -0.103965
⊟Function[edit | edit source]
- TIGRFAM: Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein YeaZ (TIGR03725; HMM-score: 185)and 3 moreProtein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein TsaD (TIGR03723; HMM-score: 29.9)Protein fate Degradation of proteins, peptides, and glycopeptides metallohydrolase, glycoprotease/Kae1 family (TIGR00329; HMM-score: 27.8)DNA metabolism DNA replication, recombination, and repair universal archaeal protein Kae1 (TIGR03722; HMM-score: 25.5)
- TheSEED :
- TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA
Cell Division and Cell Cycle Cell Division and Cell Cycle - no subcategory YgjD and YeaZ TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNAand 4 moreCell Wall and Capsule Cell Wall and Capsule - no subcategory YjeE TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNAProtein Metabolism Protein biosynthesis Ribosome biogenesis bacterial TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA - PFAM: Actin_ATPase (CL0108) TsaD; tRNA N6-adenosine threonylcarbamoyltransferase (PF00814; HMM-score: 102.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9986
- Cytoplasmic Membrane Score: 0.0003
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.0008
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.01799
- TAT(Tat/SPI): 0.000949
- LIPO(Sec/SPII): 0.00231
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAIDFLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPHQQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPFVEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTESGESYIKRL
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0134 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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