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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_1074 [new locus tag: SPJ_RS05370 ]
  • pan locus tag?: PNEUPAN002298000
  • symbol: zmpB3
  • pan gene symbol?: zmpD
  • synonym:
  • product: zinc metalloprotease ZmpB

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_1074 [new locus tag: SPJ_RS05370 ]
  • symbol: zmpB3
  • product: zinc metalloprotease ZmpB
  • replicon: chromosome
  • strand: +
  • coordinates: 1033059..1038272
  • length: 5214
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    TTGTCATTATTAAAAAAAGATAAATTTTCCATTCGGAAAATAAAGGGTATTGTTGGTTCG
    GTATTCTTGGGGAGTCTTTTATTTGCACCGTCAGTTGTTGGTGCATCGACTTATCATTAC
    TTAGATTATAGTAGTTTGACACAAACTGAACGTGATCAACTCAAACAAGGTAGACCTGAT
    GAATCCAAAGAGTCATATGCTTTGGATTATGAAAAAGACGCACTACCAAACACAGGAAGT
    TCTCAATCTATTATGACTGCATTGGGTTTGTTAGCTATCGGGAGTCTTATTGTGATTATC
    ACAAAAGATAATAGAAATAAAAAAATAGCTACATTTTTGATTGTAGGGGCGACAGGTTTA
    GTTACACTATCAACTGCTTCAGCACTTAATTTGAATGCTAACATCCATGAGTCTGGACGT
    GATGGTGTGTTGCAAATTTCTGGTTACAGATATGTTGGTTACTTGGAGCTTGATGATAAA
    ACTGTTTCGTCGGTTTCTCCAGCATCAACTGTTTCGCCAGTTGAGCAACCCAAAGTTGTA
    ACAGAGAAAGGCGAACCGGAAGTTCATGAGAAGCCTGACTATACGCAACCAATAGGTGCA
    AACCTTGTTGAGCCTGAAGTTCATGAGAAACTAGCATACACTGAACCAGTAGGGACAACA
    GGAGTAGATGAAAATGGAAACTTGATTGAACCACCTGTTAACGACATCCCAGAATATACT
    GAGCCAGTAGGTACAACAGGAGTGGATGAAAATGGAAACTTGATTGAGCCACCTGTTAGC
    GACATTCCAGAGTATACTGAACCAATATCTACAGTTTCAGAAGTTGCATCAGAAAGAGAA
    GAGTTGCCTTCTTTACATACCGATATTCGGACAGAGACTATTCCTAAAACCACTATAGAA
    GAATCTGATCCTAGCAAATTTATAGGCGATGATTCTGTTAGACAAGTTGGTGAGGATGGC
    GAACGTCAAATTGTTACTAGCTATGAAGAGTTACATGGCAAAAAAATCAGTGACCCAGTT
    GAAACAGTAACTATTTTGAAAGAAATGAAGCCTAAAATTCTTGTAAAAGGTACCAAAGAA
    AAACCTAAAGAAAAAACGGCTCCTGTTTTGACCTTAGATAGAACAAATACAAATGTATTA
    AACCGATCCGCAACTCTTTCTTATCATTTAGTTAATACAGATGGAGTCACAATCAATAAA
    ATTACTGCGACAATTAAAGATGGAAATGAAATTGTCAAAACAGTAGATTTGACTTCAGAG
    CAATTAGATAAGCAGGTAGAAGATTTAAAATTCTACAAGGACTATAAGATAGAGACCACT
    ATGACCTATGACCGTGGCAAGGGAGAAGAAACTGCAACATTAGAAGAGAAACCACTTCGC
    TTGGATTTGAAAAAAGTTGAAATTAAAAATATCGCATCTACTAATTTAGTGAAGGTAAAT
    GACGATGGTACTGAAACACCTAGTGATTTTATGACTGAAAAACCTTCAGATGAAGATGTG
    AAGAAAATGTACTTAAAAATTACTAGTCGTGATAATAAAGTAACACGTTTAGCAGTTGAT
    AAAATTGAAGAAGTGACTGAAGAAGGTAAGAAACTTTATAAAATCACTGCCGAAGCTCAA
    GATTTGATTCAACATACAGACCCAACGAAGGTTCGTAACAAGTATGTTCATTATATTGAA
    AAACCAGTTCCAAAAGTTGATGACGTTTATTATAACTTTAAAGAGTTAGTAGATGCCATG
    AATGCTGATAAAAATGGTACATTTAAAATCGGAGCAGATTTGAATGCAACGAATGTACCA
    ACACCTAACAAACAATATGTTCCAGGTACGTTTAAGGGACATCTATCAAGTGTTGATGGT
    AAACAATATACAATTCATAACATTGCCCGTCCCTTATTTGACCGTGTTGAAAATGGTTCT
    GTGAAAAATATTAATTTAGGTAATGTGGATATCAATATGCCTTGGGCTGACGGAATAGCA
    CCTGTTGCCAATATGGTGAAAAATGCAACTGTTGAAGATGTTAAGGTAACTGGTAATGTA
    GTTGCTAATAACAATATTGCGGGTATCGTCAATAAAATCGATAGTGGTGGTCAGTTGACA
    AATGTAGCCTTCATCGGTAATCTTACAGGTGTTGGTGATAAAGGTCAATATATGGCTGGC
    ATTGCCGGTGAGATTTGGAGAGGTAATCTTGCAAAAGCATATGTCGAGGCTGATATTGTT
    GCTAACAGAGCCCGTATAGGTGGTTTAGTTGCTAAAACAGATAATGGTAACGACTCTATG
    GGAATTGGTAAATACGGTTCAATTCGTAAATCAGTCACCAAAGGAACCATTAAGACTAAA
    GTTTTGTTTGAAACAGGTGGATTTATCAATAGCAATCTTCCTTTTGGTAAACTTGAAGAT
    AATATTTCAATGATGAGAGTTGAAAATGGTGAAGAGTTCTTTGGTTCTTCCGATTTGGAC
    TACGATGGTGGTTATTTCACAAATGGCTGGTTAGAGCGTAACTTTGTTGTCAAAGGTGTC
    AGTTCAGGTAAGCATTCATACAAACGTTCTCGTGACAAAATTAAAGAAATTAGTCAAGAT
    GAAGCTAATAAGAGAATTGCAAATTTTGGACTTACTGCTGATAAATACGAAATCAACGAA
    CCTGTGGTCAATCGCTTAAATCGTTTAACCAGAAGAGAAGATGAATATAAGTCAACTCAA
    GACTACAAATCCGAACGTGATTTAGCTTATCGTAATATTGAGAAACTTCAACCATTTTAT
    AATAAAGAATGGATTGTCAACCAAGGTAACAAACTTGCAGAAGATTCAAACTTAGCTAAG
    AAAGAAGTCCTTTCTGTTACGGGGATGAAGGATGGTCAATTCGTGACCGATTTATCAGAT
    ATTGATAAGATTATGGTTCACTATGCTGATGGTACTAAGGAAGAAATGGATGTTACTAAG
    AATACTGATTCTAAAGTCCAACAAGTGCGTGAATATAGTGTATCTGGTCTTGGTGATGTT
    GTTTATACACCGAATATGGTTGTTAAAAATCGTGATAAATTGATTGCTGATGTTAAATCT
    CAATTATCAAGTGTGGAATTGATTTCACAAGAAGTAAGAGATTTAATGAGTAGACGTGAT
    AAACCTGCAGAGAATACGGATGAACGTAAGAATGGTTATATTAAAGATCTATACTTAGAA
    GAAAGCTTTGCCGAAGTGAAGCAAAATCTAGATAAGTTAGTCAAATCCTTGGTCGAAAAT
    GAAGACCATCAATTGAATGGTGATGAAGCTGCGATAAAATCACTTCTCAAGAAAGTGGAA
    ACCAATAAAGCTAAAATCATGATGGCTCTGACTTATCTCAATCGTTACTATGATATCAAA
    TACGGTGACATAAGTATAAAAAACATCATGATGTTCAAACCTGATTTTTATGGTAAAACA
    CCAAGTGTTATTGACAGACTCATCAACATCGGTTCAAGTGAAAAGAACTTGAAAGGGGAT
    CGGACTCAGGATGCTTACCGTGAAATCATCGCAGGTAATACTGGTAAAAGTAATTTGCGT
    AACTTCTTAGAATACAACATGCGTCTGTTTACAGAGGATAAAGACATCAATGATTGGTTT
    ATCCACTCAGCTAAGAATGTTTATGTTTCAGAACCTAAGACAACAAATACAGAGTTGAAA
    GATAAACGTCATCGTGTGTTCGATGGTTTAGATAACGGTGTTCATGGTCGTATGATTTTA
    CCACTTCTAACGCTTAAAGATGCCCATATGTTCTTAATTTCAACATATAACACGATGGCG
    TACAGTTCATTTGAGAAATATGGAAAACATACAGAAGAAGCTCGTAATGAGTTCAAAACT
    AAGATTGATGAAGTTGCACATGCTCAACAAACTTATTTAGATTTCTGGTCCAGATTAGCT
    CTGCCTAATGTTCGTGATAGACTTCTTAAGAGTCAAAATATGGTACCGACACCAGTTTGG
    GATAACCAGACCTACAATGGTTCTCCTGTAGGTCGTCGAGGATTTGACAGTAAAGGTAAC
    CCTATAGCTCCAATTCGTGAATTATATGGTCCAACATGGCGACACCATGATAGAGACTGG
    CGTATGGGCGCTATGGCATCAATATTCCCTAATCCAAATAATGATGACAAGGTCTTGTTT
    ATGGTGACGGATATGATTAGCCCATTTGGTATTTCAGCCTTTACTCACGAAACAACACAC
    GTAAACGATAGAATGCTTTACTTCGGTGGTCATAAGCATCGTCAAGGTACAGACGTTGAA
    GCCTATGCTCAAGGTATGTTGCAAACACCTGACAGCTCAACGACTAATGGTGAATACGGC
    GCACTTGGAATTAACATGGCTTACCATCGTCCAAATGATGGTAACCAATGGTACAACCCA
    GATCCTGACAAATTAAAGACACGTGATGACATTGACCGCTACATGAGAAACTACAATGAA
    GCTATGATGTTGCTTGATCATGTAGAAGCTGATGCTGTACTTCCTAAAATTAAAGGAGAC
    AATAGTAAGTGGTTCAAGAAGATTGACAAAGAAATGCGCTCTAAGATTCAGTATAATGAT
    CTTTTAGGTCCAAACCAATGGGATAGTATCCGTGATTTGAAAGATGAAGAAAAGGTAATG
    ACTTTATCTAGCGTCAATGATTTAGTGGATAATAACTTCATGACAAAACATGGAAATCCA
    GGTAATGGACGTTATAGACCAGAAGATTTTACACCAAACTCAGCTTACGTAAATGTCAAT
    ATGATGGCAGGAATTTACGGTGGGAATACGAGTCAAGGTGCTCCTGGTTCATTATCATTT
    AAGCACAATGCTTTCCGTATGTGGGGCTATTATGGTTATGAAAATGGCTTTATTAGTTAT
    GTATCAAATAAATACAAAGCAGAAGCAGATAAAAACAACCACGGTTTACTAAGCGATAAG
    CTAATAATTAATAAAGTATCGAAAGGAAACTTTAATACTCTTGAAGAGTGGAAGAGACAT
    TGGTACGGGGAAGTTCTTGCTAAAGCTAAGAAAGGTTTTGAGGCTATCGATATTGATGGC
    GTCCATATCAGTAACTATGATGAGTTAAGGCCTTTATTTGATAAAGCAGTTGAAGAAGAT
    TTGAAGAAACCAGATGACTTCTCTCACACTGTTGCTCTTAAATCTAAGGTCTTCAAAGCC
    CTTCTTAAAAACACAGACGGTTTCTTTAATAAACTGTTTAAAGAAGACATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
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    1260
    1320
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    1560
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    2040
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    2160
    2220
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    2400
    2460
    2520
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    2640
    2700
    2760
    2820
    2880
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    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4920
    4980
    5040
    5100
    5160
    5214

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_1074 [new locus tag: SPJ_RS05370 ]
  • symbol: ZmpB3
  • description: zinc metalloprotease ZmpB
  • length: 1737
  • theoretical pI: 6.02095
  • theoretical MW: 195476
  • GRAVY: -0.629591

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 19.9)
  • TheSEED  :
    • Zinc metalloprotease zmpB precursor (EC 3.4.24.-)
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 826.5)
    and 6 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 267.7)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 36.7)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 18.2)
    KNTase_C (CL0291) HEPN_Cthe2314; Cthe_2314-like HEPN (PF18730; HMM-score: 17.3)
    no clan defined Pectate_lyase_5; Putative pectate lyase-like adhesive domain (PF20585; HMM-score: 12.7)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 8.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0003
    • Cytoplasmic Membrane Score: 0.0207
    • Cell wall & surface Score: 0.8686
    • Extracellular Score: 0.1105
  • SignalP: Signal peptide SP(Sec/SPI) length 35 aa
    • SP(Sec/SPI): 0.860775
    • TAT(Tat/SPI): 0.019935
    • LIPO(Sec/SPII): 0.012019
    • Cleavage Site: CS pos: 35-36. VGA-ST. Pr: 0.5872
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYSSLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITKDNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDKTVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGKKISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVNTDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEETATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKITSRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKVDDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYTIHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVANNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIVANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKLEDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKEISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQEVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGDEAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDRLINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSAKNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYSSFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVWDNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKVLFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTNGEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVLPKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNNFMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAKAKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTDGFFNKLFKEDI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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