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serotype 1

NCBI: 05-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_RS01485 [old locus tag: SPJ_0295 ]
  • pan locus tag?: PNEUPAN001024000
  • symbol: SPJ_RS01485
  • pan gene symbol?: yitU
  • synonym:
  • product: Cof-type HAD-IIB family hydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_RS01485 [old locus tag: SPJ_0295 ]
  • symbol: SPJ_RS01485
  • product: Cof-type HAD-IIB family hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 270118..270930
  • length: 813
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGACGAAAAAAATTATTGCAGTTGACCTAGATGGAACCCTGCTCAACTCAGACAGTCAA
    ATTTCTGACTTTACCAAAAAAACCATCAAAAAAGTTGCTGAAAAAGGCCATCAGGTTATT
    ATTACGACAGGTCGCCCTTACCGTATGTCAAAAGATTTTTACCGTGAACTGGGCTTAGAC
    ACTCCTATGATTAACTTCAACGGATCCCTTACTCATTTACCAGACCAAGTTTGGGATTTT
    GAAAAGTGTTTGACTGTAGACAAAAAATATCTGCTAGATATGGTTCAACGTTCAGAGGAC
    ATTCAAGCCGATTTTATCGCTGGAGAATATCGTAAAAAATTCTACATTACAAATCCCAAT
    GAAGAAATTGCCAATCCCAAACTATTTGGTGTAGAAGCTTTCCAGCCTGAAGATCAATTC
    CAGCCTGAATTGGTGACCAAGGACCCTAACTGTATCCTCTTGCAGACCAGAGCCAGTGAC
    AAATATGCCTTGGCAAAAGAAATGAACGCCTTCTACCAGCATCAACTTTCTATCAATACC
    TGGGGAGGTCCGCTCAATATCCTTGAATGTACCCCAAAAGGTGTCAACAAGGCCTTTGCT
    TTGGACTACTTGCTCAAGATAATGAATCGTGACAAAAAAGATTTGATTGCCTTTGGAGAT
    GAACACAATGATACCGAAATGCTCGCTTTTGCTGGGAAGGGTTATGCCATGAAAAATGCC
    AATCCAGAGCTACTCCCTTATGCAGATGAGCAAATTTCCCTTACCAACGACCAAGATGGG
    GTTGCCAAAACCCTACAAGACTTATTCTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    813

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_RS01485 [old locus tag: SPJ_0295 ]
  • symbol: SPJ_RS01485
  • description: Cof-type HAD-IIB family hydrolase
  • length: 270
  • theoretical pI: 4.9356
  • theoretical MW: 30748.9
  • GRAVY: -0.447037

⊟Function[edit | edit source]

  • reaction:
    EC 3.-.-.-?  ExPASy
  • TIGRFAM:
    Unknown function Enzymes of unknown specificity Cof-like hydrolase (TIGR00099; HMM-score: 178.7)
    and 17 more
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIB (TIGR01484; HMM-score: 93.3)
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 66.4)
    sucrose-phosphate phosphatase subfamily (TIGR01482; EC 3.1.3.-; HMM-score: 61.8)
    mannosyl-3-phosphoglycerate phosphatase family (TIGR01486; EC 3.1.3.-; HMM-score: 45.8)
    Unknown function General mannosyl-3-phosphoglycerate phosphatase homolog (TIGR02463; EC 3.1.3.-; HMM-score: 40.1)
    mannosyl-3-phosphoglycerate phosphatase (TIGR02461; EC 3.1.3.70; HMM-score: 35.5)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IB (TIGR01490; HMM-score: 33.4)
    sucrose phosphatase (TIGR01485; EC 3.1.3.24; HMM-score: 31.5)
    Unknown function Enzymes of unknown specificity HAD phosphoserine phosphatase-like hydrolase, family IB (TIGR01488; HMM-score: 29)
    sucrose-phosphate synthase, sucrose phosphatase-like domain (TIGR02471; HMM-score: 23.9)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIIA (TIGR01662; HMM-score: 21.2)
    Metabolism Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 18.1)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family (TIGR01670; EC 3.1.3.45; HMM-score: 15.8)
    phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 13.1)
    pyrimidine 5'-nucleotidase (TIGR01993; EC 3.1.3.5; HMM-score: 12.5)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIA (TIGR01460; HMM-score: 11.9)
    plasma-membrane proton-efflux P-type ATPase (TIGR01647; EC 3.6.3.6; HMM-score: 11)
  • TheSEED: see SPJ_0295
  • PFAM:
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 204.2)
    and 6 more
    S6PP; Sucrose-6F-phosphate phosphohydrolase (PF05116; HMM-score: 53.9)
    HAD; haloacid dehalogenase-like hydrolase (PF12710; HMM-score: 30.9)
    Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 26.6)
    Trehalose_PPase; Trehalose-phosphatase (PF02358; HMM-score: 18.7)
    HAD_2; haloacid dehalogenase-like hydrolase (PF13419; HMM-score: 14.8)
    no clan defined DUF460; Protein of unknown function (DUF460) (PF04312; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9969
    • Cytoplasmic Membrane Score: 0.002
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0009
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0073
    • TAT(Tat/SPI): 0.000388
    • LIPO(Sec/SPII): 0.001072
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTGRPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASDKYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAFGDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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