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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034183
  • locus tag: SPN034183_03500 [new locus tag: SPN034183_RS01880 ]
  • pan locus tag?: PNEUPAN001089000
  • symbol: mraW
  • pan gene symbol?: rsmH
  • synonym:
  • product: S-adenosyl-methyltransferase MraW

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034183_03500 [new locus tag: SPN034183_RS01880 ]
  • symbol: mraW
  • product: S-adenosyl-methyltransferase MraW
  • replicon: chromosome
  • strand: +
  • coordinates: 333069..334019
  • length: 951
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: FQ312043 (333069..334019) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0304 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGACAAAAGAATTTCATCATGTAACGGTCTTACTCCACGAAACGATTGATATGCTTGAC
    GTAAAACCTGACGGTATCTACGTTGATGCGACTTTGGGTGGAGCAGGCCATAGCGAGTAT
    TTATTAAGTAAATTAAGTGAAAAAGGCCATCTCTATGCCTTTGACCAGGATCAGAATGCC
    ATTGACAATGCGCAAAAACGCTTGGCACCTTACATTGAGAAGGGAATGGTGACCTTTATC
    AAGGATAACTTCCGTCATTTACAGGCACGTTTGCGCGAAGCTGGTGTTCAGGAAATTGAT
    GGAATTTGTTATGACTTGGGAGTGTCTAGTCCTCAATTGGACCAGCGTGAGCGTGGTTTT
    TCTTATAAAAAGGATGCGCCACTGGACATGCGGATGAATCAGGATGCTAGTCTGACAGCC
    TATGAAGTGGTTAATCATTATGACTATCATGATTTGGTTCGTATTTTCTTCAAATACGGT
    GAGGATAAATTCTCTAAACAGATTGCGCGTAAGATTGAGCAAGCGCGTGAAGTGAAGCCG
    ATTGAGACAACGACTGAGTTAGCAGAGATTATCAAGTTGGTCAAACCTGCCAAGGAACTC
    AAGAAGAAGGGTCATCCTGCTAAGCAGATTTTCCAGGCTATTCGAATTGAAGTCAATGAT
    GAACTGGGAGCGGCAGATGAGTCCATCCAGCAGGCTATGGATATGTTGGCTCTGGATGGT
    AGAATTTCAGTGATTACCTTTCATTCCTTAGAAGACCGCTTGACCAAGCAATTGTTCAAG
    GAAGCTTCAACAGTTGAAGTTCCAAAAGGCTTGCCTTTCATCCCAGATGATCTCAAGCCC
    AAGATGGAATTGGTGTCCCGTAAGCCAATCTTGCCAAGTGCGGAAGAGTTAGAAGCCAAT
    AACCGCTCGCACTCAGCCAAGTTGCGCGTGGCCAGAAAAATTCACAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    951

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034183_03500 [new locus tag: SPN034183_RS01880 ]
  • symbol: MraW
  • description: S-adenosyl-methyltransferase MraW
  • length: 316
  • theoretical pI: 6.97533
  • theoretical MW: 36023
  • GRAVY: -0.499684

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification 16S rRNA (cytosine(1402)-N(4))-methyltransferase (TIGR00006; EC 2.1.1.199; HMM-score: 394.5)
  • TheSEED  :
    • rRNA small subunit methyltransferase H
  • PFAM:
    NADP_Rossmann (CL0063) Methyltransf_5; MraW methylase family (PF01795; HMM-score: 451.6)
    and 6 more
    rRNA_methylase; Putative rRNA methylase (PF06962; HMM-score: 22.3)
    GCD14; tRNA methyltransferase complex GCD14 subunit (PF08704; HMM-score: 18.5)
    Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 17.7)
    FtsJ; FtsJ-like methyltransferase (PF01728; HMM-score: 15.8)
    Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 15.5)
    no clan defined FlhC; Flagellar transcriptional activator (FlhC) (PF05280; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9989
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006045
    • TAT(Tat/SPI): 0.000307
    • LIPO(Sec/SPII): 0.000392
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCP32060 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSKLSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGICYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYGEDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPDDLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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