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serotype 4
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serotype 23F
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HU-OH
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Hu17
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INV200
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JJA
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NCTC7465
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NCTC7466
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NU83127
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SP49
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SPN032672
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SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
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SPNA45
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ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 06-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F03220 [new locus tag: SPN23F_RS01665 ]
  • pan locus tag?: PNEUPAN001127000
  • symbol: wchA
  • pan gene symbol?: cps2E
  • synonym:
  • product: undecaprenylphosphate glucosephosphotransferase WchA (initial sugar transferase)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F03220 [new locus tag: SPN23F_RS01665 ]
  • symbol: wchA
  • product: undecaprenylphosphate glucosephosphotransferase WchA (initial sugar transferase)
  • replicon: chromosome
  • strand: +
  • coordinates: 307152..308519
  • length: 1368
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAATGAAAAAATATTAAGATCTTCATTGGCCATAATTCAGAGTTTTCTTGTTATTTTA
    TTGACTTATCTACTTAGTGCTGTGAGAGAAACGGAGATTGTTTCAACAACAGCTATTGCA
    CTTTATATCCTCCATTATTTTGTCTTTTATATCAGTGATTATGGACAGGATTTCTTTAAA
    AGGAGATATTTGATTGAACTTGTCCAGACATTGAAATATATCCTATTCTTTGCACTAGCG
    ATTGGTATTTCTAATTTTTTCTTAGAGGATCGATTTAGTATTTCCAGACGAGGCATGATT
    TACTTCCTCACATTACATGCTCTCTTAGTCTATGTGCTAAACCTATTTATCAAGTGGTAT
    TGGAAGCGGGCTTATCCCAACTTTAAAGGAAGTAAGAAGATTCTCTTACTTACAGCAACT
    TCTCGTGTCGAAAAGGTACTGGATAGATTAATAGAATCAAATGAGGTTGTTGGGAAGTTG
    GTAGCCGTCAGTGTCTTAGATAAACCAGATTTTCAGCATGATTGTTTAAAGGTAGTAGCA
    GAGGGGGAGATAGTAAACTTTGCGACTCATGAGGTGGTCGATGAAGTCTTTATCAATCTT
    CCAGGTGAAAAATACAATATTGGAGAGCTTGTCTCTCAGTTTGAAACGATGGGAATTGAT
    GTAATAGTCAATCTAAATGCTTTTGATCGTAGTTTGGCACGTAACAAGCAAATTCGTGAG
    ATGGCAGGGTTAAACGTTGTGACTTTTTCTACAACATTTTATAAGACTAGTCATGTAATT
    GCTAAGCGGATTATTGATATCGTGGGTGCATTGGTAGGGCTGATACTATGTGGTTTAGTC
    AGTATTGTACTGGTTCCTTTGATTCGAAAGGATGGGGGATCTGCTATTTTTGCTCAGACG
    CGTATAGGAAAAAATGGTCGTCAGTTCACTTTTTATAAGTTTCGCTCTATGTGTGTAGAT
    GCCGAGGCGAAAAAAAGAGAACTCATGGAACAAAATACCATGCAAGGTGGAATGTTTAAG
    GTGGACGATGATCCTCGTATCACGAAAATTGGTTGTTTTATACGGAAGACTAGCTTGGAC
    GAGCTACCACAGTTTTATAATGTTCTAAAGGGAGATATGAGTTTGGTTGGCACACGGCCA
    CCAACAGTGGACGAGTATGAGCACTATACCCCAGAACAAAAACGCCGACTAAGTTTTAAA
    CCTGGCATAACAGGTTTATGGCAGGTCAGCGGACGAAGTGAGATCAAGAATTTCGATGAA
    GTTGTCAAATTAGATGTGGCCTATATTGATGGTTGGACAATCTGGAAAGATATTGAAATT
    TTATTGAAGACAGTTAAAGTAGTATTTATGAGAGATGGAGCGAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1368

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F03220 [new locus tag: SPN23F_RS01665 ]
  • symbol: WchA
  • description: undecaprenylphosphate glucosephosphotransferase WchA (initial sugar transferase)
  • length: 455
  • theoretical pI: 9.43132
  • theoretical MW: 52160.8
  • GRAVY: 0.166813

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.8.-?  ExPASy
  • TIGRFAM:
    exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (TIGR03025; HMM-score: 392.5)
    and 5 more
    undecaprenyl-phosphate galactose phosphotransferase WbaP (TIGR03022; EC 2.7.8.6; HMM-score: 279.9)
    undecaprenyl-phosphate glucose phosphotransferase (TIGR03023; EC 2.7.8.-; HMM-score: 271.8)
    sugar transferase, PEP-CTERM system associated (TIGR03013; HMM-score: 164.7)
    archaeosortase A (TIGR04125; EC 3.4.22.-; HMM-score: 12.8)
    Hypothetical proteins Conserved TIGR00659 family protein (TIGR00659; HMM-score: 5.9)
  • TheSEED  :
    • Galactosyl transferase CpsE (EC 2.7.8.-)
    Cell Wall and Capsule Capsular and extracellular polysacchrides Extracellular Polysaccharide Biosynthesis of Streptococci  Galactosyl transferase CpsE (EC 2.7.8.-)
  • PFAM:
    no clan defined Bac_transf; Bacterial sugar transferase (PF02397; HMM-score: 218.2)
    and 1 more
    NADP_Rossmann (CL0063) CoA_binding_3; CoA-binding domain (PF13727; HMM-score: 26.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.9985
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0012
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.046413
    • TAT(Tat/SPI): 0.001746
    • LIPO(Sec/SPII): 0.080772
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CAR68179 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNEKILRSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYILHYFVFYISDYGQDFFKRRYLIELVQTLKYILFFALAIGISNFFLEDRFSISRRGMIYFLTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKLVAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPGEKYNIGELVSQFETMGIDVIVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLILCGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTMQGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVFMRDGAK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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