From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 06-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F04390 [new locus tag: SPN23F_RS02255 ]
  • pan locus tag?: PNEUPAN001362000
  • symbol: SPN23F04390
  • pan gene symbol?: mtsA
  • synonym:
  • product: putative membrane protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F04390 [new locus tag: SPN23F_RS02255 ]
  • symbol: SPN23F04390
  • product: putative membrane protein
  • replicon: chromosome
  • strand: +
  • coordinates: 423891..424439
  • length: 549
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGAAATCAAATTTACAATTAAACAAGTTGTTGCTGTCGGAATTGGCGCTGCCCTCTTT
    GTCGTCATCGGGATGATCAACATTCCAACCCCTGTTCCAAATACAAGCATCCAGCTTCAG
    TATGCGGTACAAGCGCTACTTTCTATTATTTTTGGACCGATTATCGGTTTGCTTGTCGGG
    TTGATTGGTCATGCAATCAAGGACTCTCTTGCTGGTTATGGTCTATGGTGGACTTGGATT
    ATCGCTAGCGGACTCTTTGGTCTAGTTGTGGGACTTTTTAGAAAGTACGTTCGAGTGATC
    AATGGTGTTTTTGACTGGAAAGATATTCTTATTTTTAACCTCATTCAACTACTTGCAAAT
    GCCCTTGTTTGGGGTGTCTTGGCACCACTTGGAGATGTTGTGATTTATCAAGAAGCGGCA
    GAAAAAGTATTTGCACAAGGGATTGTTGCGGGAATTGCCAATGGTGTATCTGTAGCTATT
    GCAGGAACTCTTCTCTTACTTGCCTATGCAGGAACCCAAACTCGTGCAGGAAGTTTGAAA
    AAGGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    549

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F04390 [new locus tag: SPN23F_RS02255 ]
  • symbol: SPN23F04390
  • description: putative membrane protein
  • length: 182
  • theoretical pI: 9.71498
  • theoretical MW: 19315
  • GRAVY: 1.01593

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate ECF transporter S component, folate family (TIGR04518; HMM-score: 37.4)
    and 1 more
    putative exosortase-associated protein, TIGR04073 family (TIGR04073; HMM-score: 12.2)
  • TheSEED  :
    • Substrate-specific component MtsA of methionine-regulated ECF transporter
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  Substrate-specific component MtsA of methionine-regulated ECF transporter
    and 1 more
    Membrane Transport Membrane Transport - no subcategory ECF class transporters  Substrate-specific component MtsA of methionine-regulated ECF transporter
  • PFAM:
    Gx_transp (CL0315) ECF-ribofla_trS; ECF-type riboflavin transporter, S component (PF07155; HMM-score: 187.1)
    and 4 more
    ECF_trnsprt; ECF transporter, substrate-specific component (PF12822; HMM-score: 24)
    5TM-5TMR_LYT; 5TMR of 5TMR-LYT (PF07694; HMM-score: 19.4)
    no clan defined DUF5671; Domain of unknown function (DUF5671) (PF18920; HMM-score: 15.8)
    Gx_transp (CL0315) CbiM; Cobalt uptake substrate-specific transmembrane region (PF01891; HMM-score: 15.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.053736
    • TAT(Tat/SPI): 0.001404
    • LIPO(Sec/SPII): 0.065435
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVINGVFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAIAGTLLLLAYAGTQTRAGSLKKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: MtaR* (repression) regulon
    MtaR*(TF)important in Methionine metabolism; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPN23F04390&oldid=55891"