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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 06-FEB-2015
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
- locus tag: SPN23F21990 [new locus tag: SPN23F_RS11305 ]
- pan locus tag?: PNEUPAN003834000
- symbol: fucK
- pan gene symbol?: fucK
- synonym:
- product: putative fuculokinase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN23F21990 [new locus tag: SPN23F_RS11305 ]
- symbol: fucK
- product: putative fuculokinase
- replicon: chromosome
- strand: -
- coordinates: 2145144..2146547
- length: 1404
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: FM211187 (2145144..2146547) NCBI
- BioCyc: see SPN23F_RS11305
- MicrobesOnline: 5832032 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1995 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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1381ATGGAAGCGGTTTTAGCAATAGATTTAGGTGCGACTTCTGGAAGAGCAATCGTTGGTTAC
CTTTCTGAAAATAAACTGGTAATGGAAGAAATAAATCGCTTTTCTAATCTACCTATTAGA
GTAAAAGGGCATTTATCTTGGGATATTGACTTTCTACTAGCTAAAATTCTTGAAAGTATC
CGCTTGGCTAATACTAGTTACAAGATTTTATCTATCGGTATTGACACATGGGGAGTTGAT
TTTGGACTGATTGATAATGAAGGTAAGCTGTTATTACAACCTGTTCATTATCGTGATGAA
AGAACAAAGGGAGTGTTAAAGGAAATATCTGAAATGACTGAATTAGAAAAACTGTATTCA
GAGACAGGAAATCAGATTATGGAGATAAATACCTTGTTTCAACTCTTTAAGGCACGTCAA
GAATCTCCTGACTCTTTCTATAAGACCAATAAGATTCTTTTAATGCCAGATTTGTTTAAT
TATCTCTTGACAGGTAAGTTTTCTACAGAAAAAAGCATTGCTTCAACAACTCAATTATTT
GATCCTAGGAGTCAAAATTGGAATCAGAATATCTTAAAACTATTTGAATTGGATTCATCT
TTACTTCCTGAAATTGTTTCAGAGGGAAATGTTCTTGGAAGGATAAAAAAGGAGTATGGT
TTAGGCGATATTCCTGTTGTGAATGTTTGTAGTCATGATACAGCAAGTGCGATTGTCTCA
GTACCTAAGACAGAAGGTAGTTTATTTATTTCATCAGGTACTTGGTCTTTGGTTGGAGTG
GAACTTACTTCACCGATTCTTACTACCGAATCCTTCAGTTATGGATTTACAAATGAAGTC
GGTAAAGATGGAGAGATTACATTTCTGAAGAATTGTACAGGGTTGTGGATCATAGAGGAA
CTAAGACGTTCATTTGAACGAAGAGGGAAAGCCTATTCTTTTGATGATATTAGGACAATG
GTGGAGAAAGAAAAAGAAAATCTTCCTCTGATTGATACTGAATCAACTGAATTTGCAACA
GAATCTGATATGCACAAGACTTTGACAGAATATCTAGCTTATCATCATGAAACTAGAGAG
TGGACAGATGGACAACTATTTAAGATTGTTTATGAAAGCCTAGCTGAAACGTATAGGAAA
GCGATAGAGTTACTAGAAGAACTAACTCATAAGGTTTATAAGAGGATATATGTGATTGGA
GGAGGTGCTAGAGCCAGTTACTTTAACCAAATGATTGCTGATAGAACTGGTAAAGAGGTT
CTTACAGGTTCGACTGAGGGTACAGCTGTGGGGAATATTGTTGTGCAGCTCATAGCTATG
GGACAATTAAAAGGGATGGAAGAAGCTCACCATGTTATTGAGGAGTTTCTACAATTAGAG
AGTTATTACTCCCAAAAGAATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F21990 [new locus tag: SPN23F_RS11305 ]
- symbol: FucK
- description: putative fuculokinase
- length: 467
- theoretical pI: 4.80502
- theoretical MW: 52896.9
- GRAVY: -0.219914
⊟Function[edit | edit source]
- reaction: EC 2.7.1.5? ExPASyRhamnulokinase ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate
- TIGRFAM: rhamnulokinase (TIGR02627; EC 2.7.1.5; HMM-score: 419)and 4 moreEnergy metabolism Sugars L-fuculokinase (TIGR02628; EC 2.7.1.51; HMM-score: 165.3)Energy metabolism Sugars xylulokinase (TIGR01312; EC 2.7.1.17; HMM-score: 125.4)Energy metabolism Other glycerol kinase (TIGR01311; EC 2.7.1.30; HMM-score: 68.3)Energy metabolism Sugars gluconate kinase (TIGR01314; EC 2.7.1.12; HMM-score: 60.7)
- TheSEED :
- L-fuculokinase (EC 2.7.1.51)
- PFAM: Actin_ATPase (CL0108) FGGY_N; FGGY family of carbohydrate kinases, N-terminal domain (PF00370; HMM-score: 119.5)and 1 moreFGGY_C; FGGY family of carbohydrate kinases, C-terminal domain (PF02782; HMM-score: 68.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003574
- TAT(Tat/SPI): 0.000128
- LIPO(Sec/SPII): 0.000947
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CAR69932 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGHLSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERTKGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFNYLLTGKFSTEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKEYGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGFTNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTESTEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKVYKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAHHVIEEFLQLESYYSQKN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: fucI < SPN23F21910 < SPN23F21920 < SPN23F21930 < SPN23F21940 < SPN23F21950 < SPN23F21960 < fucU < fucA < fucK
⊟Regulation[edit | edit source]
- regulators: FucR* (repression) regulon, CcpA regulon
FucR* (TF) important in Fucose utilization; RegPrecise CcpA (TF) important in Global catabolite repression; RegPrecise
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1995 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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