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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS00165 [old locus tags: SPN23F00270 SPN23F_00270 ]
  • pan locus tag?: PNEUPAN000512000
  • symbol: SPN23F_RS00165
  • pan gene symbol?: —
  • synonym:
  • product: type I restriction endonuclease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS00165 [old locus tags: SPN23F00270 SPN23F_00270 ]
  • symbol: SPN23F_RS00165
  • product: type I restriction endonuclease
  • replicon: chromosome
  • strand: -
  • coordinates: 27604..28674
  • length: 1071
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_011900 (27604..28674) NCBI
  • BioCyc: SPN23F_RS00165 BioCyc
  • MicrobesOnline: see SPN23F00270
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGAAATTGATAAAGTAAAAGCCGATTTAAAACAAGTCGGCAAACGTGTAGCAGACCTC
    AGCCAAAGCATTACGAATGAAGAACAAACAAAGAATGCCTTCATTATGCCGTTCTTCCAA
    GCGCTTGGATATGATATCTTCAATCCACTTGAATTTGTCCCGGAATTTACTGCCGACGTG
    GGCATTAAAAAAGGCGAAAAAGTCGACTATGCGATCATTTTGGATGGCGAGCCTCAAATC
    CTAATTGAATGTAAATCAATTACAGAAAACCTTACTAAGCACGACTCTCAACTATTCAGA
    TATTTCGTAACTACTAAATCAAAATTCGGTATCTTGACAAATGGTAGAGAATATAAATTC
    TTTACTGATTTAGATGAGCCAAATAAAATGGACACAACTCCATTCTTAACAATCGATGTG
    ACTGATATCAAAGAAAATCAATTTACTGAAATCATCAAATTCCACAAAGAGAATTTTGAT
    ATTGATAATATTGTTTCATCAGCTTCTGAATTGAAATACCTCAACAATCTTAAAGCGTTC
    CTTACTGAAAATATCACTACACCGTCAGATAGCTTCCTCAGATATCTAACTTCTGAAATC
    TATGAAGGGCGTGTTACTCAAAATATCTTAACGACATTTTCTCCCATTATTGTGAAAGGG
    TTTAATCAATTCATCACAGAGCGAGTTAATGAAAAATTAAGTGCTGCACTTAATACAAGC
    GTTGAAACCAAAGTAACAACCGATATTCCAAAAGTTGAAGCTGAAGCTGAAGAGATTGTC
    GAAGTAACTGACGAAATTATCACAACTCCTGCTGAATTAGAAGTTTATACTGTTGTTAAA
    ATGCTTGCTAGGGATGTAGTTTCTCCAGAACGTGTATTTTACAGAGATAACCGTAGCTAT
    TTCAATGTTTTGGTTGACGATAACATCAAAAAATGGGTATTACGTTATCGTTCAAATTCA
    AAAAAAAGCACTATCGAAATCCGTGATAAAGGCATCTTCCCGGTGTCTACCCCTCTCGAA
    GTCGCAAATTATGCCAATGAAATTTTAGAAGTAATCAAGAAATTCTCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1071

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS00165 [old locus tags: SPN23F00270 SPN23F_00270 ]
  • symbol: SPN23F_RS00165
  • description: type I restriction endonuclease
  • length: 356
  • theoretical pI: 4.65005
  • theoretical MW: 40886.2
  • GRAVY: -0.278371

⊟Function[edit | edit source]

  • TIGRFAM:
    GxxExxY protein (TIGR04256; HMM-score: 20.7)
  • TheSEED: see SPN23F00270
  • PFAM:
    PDDEXK (CL0236) HSDR_N; Type I restriction enzyme R protein N terminus (HSDR_N) (PF04313; HMM-score: 50.1)
    HSDR_N_2; Type I restriction enzyme R protein N terminus (HSDR_N) (PF13588; HMM-score: 44.1)
    and 2 more
    PDDEXK_3; PD-(D/E)XK nuclease superfamily (PF13366; HMM-score: 21.7)
    no clan defined DUF4315; Domain of unknown function (DUF4315) (PF14193; HMM-score: 7.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8974
    • Cytoplasmic Membrane Score: 0.003
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0992
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00193
    • TAT(Tat/SPI): 0.000211
    • LIPO(Sec/SPII): 0.000509
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000401841 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGYDIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYFVTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFDIDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIVKGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVYTVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFPVSTPLEVANYANEILEVIKKFS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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